Results 41 to 50 of about 24,830 (176)

Biogenesis and adhesion of type 1 and P pili

, 2014
- Background: Uropathogenic Escherichia coli (UPEC) cause urinary tract infections (UTIs) in approximately 50% of women. These bacteria use type 1 and P pili for host recognition and attachment.
Lillington, J., Geibel, Sebastien, Waksman, Gabriel   +2 more
core   +1 more source

Catch-bond mechanism of the bacterial adhesin FimH [PDF]

, 2016
Ligand-receptor interactions that are reinforced by mechanical stress, so-called catch-bonds, play a major role in cell-cell adhesion. They critically contribute to widespread urinary tract infections by pathogenic Escherichia coli strains.
Sauer, Maximilian M., Navarra, Giulio, Bernèche, Simon, Maier, Timm, Eras, Jonathan, Glockshuber, Rudi, Jakob, Roman P., Ernst, Beat, Baday, Sefer, Eris, Deniz   +9 more
core   +1 more source

CS20 bridge the gap between class 1 and class 5 bacterial adhesion pili

, 2022
Enterotoxigenic Escherichia coli (ETEC) are pathogenic bacteria that cause diarrheal disease that disrupts the nutrition and the growth of children under the age of 5 and causes illness in travelers to countries where these bacteria are endemic.
Dahlberg, Tobias,, Baker, Joseph, Andersson, Magnus,, Bullitt, Esther, Doran, Matthew   +4 more
core   +1 more source

Binding of E. coli expressing P pili and type 1 pili in SPR assay.

, 2013
Each type of bacteria (P pili-black line and type 1 pili-gray line) was injected into the flow chambers five times and washed with buffer at pH 7.0 between each injection.
Mickaël Castelain (320432), Jeanna E. Klinth (320430), Ove Axner (320435), Bernt Eric Uhlin (107126)   +3 more
core   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Functional characterization of a mucus-specific LPXTG surface adhesin from probiotic Lactobacillus rhamnosus GG

, 2011
In spite of the wealth of clinical evidence supporting the health benefits of Lactobacillus rhamnosus GG in humans, there is still a lack of understanding of the molecular mechanisms behind its probiosis.
Vos, W.M., de, Vanderleyden, Jos, De Keersmaecker, Sigrid, Sarah Lebeer, Ossowski, I., von, von Ossowski, I., Reunanen, J., Jos Vanderleyden, Ingemar von Ossowski, Sigrid C. J. De Keersmaecker, Satokari, R., Justus Reunanen, Willem M. de Vos, Lebeer, Sarah, Palva, A., de Vos, W.M., Reetta Satokari, Airi Palva   +17 more
core   +1 more source

Cryo-electron microscopy reveals two distinct type IV pili assembled by the same bacterium [PDF]

, 2020
Type IV pili are flexible filaments on the surface of bacteria, consisting of a helical assembly of pilin proteins. They are involved in bacterial motility (twitching), surface adhesion, biofilm formation and DNA uptake (natural transformation). Here, we
Kruse, Kerstin, Neuhaus, Alexander, Neuhaus, A., Sanders, K., Gold, V., Selvaraj, Muniyandi, Selvaraj, M., Gold, Vicki A. M., Averhoff, Beate, Langer, Julian David, Averhoff, B., Langer, Julian D., Salzer, R., Salzer, Ralf, Daum, Bertram, Daum, B., Kirchner, L., Sanders, Kelly, Kirchner, Lennart, Kruse, K., Langer, J. ; https://orcid.org/   +20 more
core   +1 more source

Novel pili-like surface structures of Halobacterium salinarum strain R1 are crucial for surface adhesion

Frontiers in Microbiology, 2015
It was recently shown that haloarchaeal strains of different genera are able to adhere to surfaces and form surface-attached biofilms. However the surface structures mediating the adhesion were still unknown.
Gerald eLosensky, Lucia eVidakovic, Andreas eKlingl, Andreas eKlingl, Felicitas ePfeifer, Sabrina eFröls   +5 more
doaj   +1 more source

Production of pili, hemolysin and siderophores in the urinary isolates of Escherichia coli [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2013
Introduction. Escherichia coli (E. coli) are the most frequent cause of the urinary tract infections. Uropathogenic E. coli (UPEC) produce virulence factors which enable them to survive in the urinary tract and cause an infection. Objective.
Marković Tatjana, Šmitran Aleksandra, Petković Miroslav   +2 more
doaj   +1 more source

Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip

Advanced Science, EarlyView.
In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao, Dongyu Xu, Minhui Lu, Yuanjin Zhao   +3 more
wiley   +1 more source