Results 51 to 60 of about 24,830 (176)

Role of meprins to protect ileal mucosa of Crohn's disease patients from colonization by adherent-invasive E. coli. [PDF]

open access: yesPLoS ONE, 2011
Ileal lesions in Crohn's disease (CD) patients are colonized by pathogenic adherent-invasive Escherichia coli (AIEC) able to adhere to and invade intestinal epithelial cells (IEC), and to survive within macrophages.
Emilie Vazeille   +9 more
doaj   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

open access: yesAdvanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang   +8 more
wiley   +1 more source

The structure of the PapD-PapGII pilin complex reveals an open and flexible P5 pocket

open access: yes, 2012
P pili are hairlike polymeric structures that mediate binding of uropathogenic Escherichia coli to the surface of the kidney via the PapG adhesin at their tips.
Pinkner, J.   +16 more
core   +1 more source

Modulation of Animal Gut Health by Milk Oligosaccharide

open access: yesAnimal Research and One Health, EarlyView.
This review summarizes the composition and structural characteristics of MOs across different mammalian species, and elucidates their roles and mechanisms in maintaining intestinal homeostasis by regulating gut microbiome and enhancing intestinal chemical, physical and immune barriers.
Ningtao Chen   +7 more
wiley   +1 more source

The Mechanical Properties of E. coli Type 1 Pili Measured by Atomic Force Microscopy Techniques

open access: yes, 2006
The first step in the encounter between a host and a pathogen is attachment to the host epithelium. For uropathogenic Escherichia coli, these interactions are mediated by type 1 and P adhesive pili, which are long (∼1μm) rods composed of more than 1000 ...
Garcia, Tzintzuni   +3 more
core   +1 more source

Evaluation of the role of Mycobacterium tuberculosis pili (MTP) as an adhesin, invasin, and cytokine inducer of epithelial cells

open access: yesBrazilian Journal of Infectious Diseases, 2016
This study was undertaken in order to assess the involvement of Mycobacterium tuberculosis pili (MTP) as an adhesin, invasin, and cytokine inducer in the M. tuberculosis-epithelial cell interaction. A MTP-deficient strain of M.
Saiyur Ramsugit   +2 more
doaj   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi   +1 more
wiley   +1 more source

Control of pili synthesis and putrescine homeostasis in Escherichia coli

open access: yeseLife
Polyamines are biologically ubiquitous cations that bind to nucleic acids, ribosomes, and phospholipids and, thereby, modulate numerous processes, including surface motility in Escherichia coli.
Iti Mehta   +6 more
doaj   +1 more source

A Review on Carbon‐Based and Metal‐Based Anode Materials of Microbial Fuel Cells

open access: yesEnergy Science &Engineering, EarlyView.
Reviews a wide range of anode materials used in microbial fuel cells (MFCs) and evaluates their performance and suitability for scalable energy recovery from wastewater. Defines the essential characteristics of an ideal anode, including high surface area, excellent electrical conductivity, strong biocompatibility, and cost‐effectiveness, while ...
Md. Hamidur Rahman   +1 more
wiley   +1 more source

Molecular mechanism of bacterial type 1 and P pili assembly

open access: yes, 2015
The formation of adhesive surface structures called pili or fimbriae (‘bacterial hair’) is an important contributor towards bacterial pathogenicity and persistence. To fight often chronic or recurrent bacterial infections such as urinary tract infections,
Waksman, Gabriel, Busch, A., Phan, G.
core   +1 more source

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