Results 11 to 20 of about 1,627,676 (310)
Adiposity-Related Heterogeneity in Patterns of Type 2 Diabetes Susceptibility Observed in Genome-Wide Association Data [PDF]
, 2009 OBJECTIVE-This study examined how differences in the BMI distribution of type 2 diabetic case subjects affected genome-wide patterns of type 2 diabetes, association mid considered the implications for the etiological heterogeneity of type 2 diabetes ...Timpson, NJ, David P. Strachan, Weedon, Michael N., Weedon, MN, Nicholas J. Timpson, Rayner, NW, Morris, Andrew D., Zeggini, Eleftheria, Mark Walker, Alex S.F. Doney, Doney, ASF, Palmer, Colin N A, Timothy M. Frayling, Strachan, David P., Hitman, Graham A., Lindgren, Cecilia M., Hattersley, Andrew T., Hitman, GA, Lindgren, CM, Randall, Joshua, Doney, Alex S. F.; id_orcid, Graham A. Hitman, Andrew T. Hattersley, Walker, Mark, Palmer, CN, Hattersley, AT, Rayner, N. William, McCarthy, MI, Timpson, Nicholas J., Michael N. Weedon, Willem H. Ouwehand, Palmer, CNA, Walker, M, Andrew D. Morris, Doney, Alex S F, N. William Rayner, Lindgren, Cecilia, Randall, J, Mark I. McCarthy, Frayling, Timothy M., Strachan, DP, Morris, AD, Cecilia M. Lindgren, Doney, AS, Joshua Randall, McCarthy, Mark I., Zeggini, E, Eleftheria Zeggini, Ouwehand, WH, Pamler, CAN, Ouwehand, Willem H., Colin N.A. Palmer, Frayling, TM, Palmer, Colin N. A.; id_orcid +53 morecore +1 more sourceType 2 Diabetes Risk Alleles Are Associated With Reduced Size at Birth [PDF]
, 2009 OBJECTIVE: Low birth weight is associated with an increased risk of type 2 diabetes. The mechanisms underlying this association are unknown and may represent intrauterine programming or two phenotypes of one genotype.Timpson, NJ, Ruokonen, A, Weedon, Michael N, Hattersley, AT, McCarthy, MI, Pouta, Anneli, Lindgren, Cecilia M, Perry, JR, Weedon, MN, Elliott, P, Groves, Christopher J, Smith, GD, Shields, B, Power, C, Järvelin, MR, Hyppönen, E, Shields, Beverley, Zeggini, Eleftheria, McCarthy, Mark I, Bennett, Amanda J, Ring, Susan M, Power, Chris, Ring, SM, Ruokonen, Aimo, Pouta, A, Strachan, DP, Elliott, Paul, Järvelin, Marjo-Riitta, Timpson, Nicholas J, Lango, Hana, Groves, CJ, Bennett, AJ, Hattersley, Andrew T, Lindgren, CM, Smith, George Davey, Zeggini, E, Frayling, Timothy M, Strachan, David P, Lango, H, Hyppönen, Elina, Freathy, RM, Perry, John R B, Frayling, TM, Freathy, Rachel M +43 morecore +1 more sourceSkin microvascular vasodilatory capacity in offspring of two parents with Type 2 diabetes [PDF]
, 2001 Aims<br/> Microvascular dysfunction occurs in Type 2 diabetes and in subjects with fasting hyperglycaemia. It is unclear whether this dysfunction relates to dysglycaemia.Shore, A.C., Lowe, G.D., Lee, B.C., B. C. Lee, Clark, P.M., A. Rumley, J. E. Tooke, A. T. Hattersley, Rumley, A., Tooke, J.E., G. D. Lowe, A. C. Shore, J. M. Humphreys, Humphreys, J.M., P. M. Clark, Hattersley, A.T. +15 morecore +1 more sourceGenetics of type 2 diabetes [PDF]
Current Opinion in Clinical Nutrition and Metabolic Care, 2010 To provide an overview of the genetics of type 2 diabetes in the context of recent progress in the understanding of the genetic architecture of the disease and its applicability to the pathogenesis of the disease as well as efforts to individualize therapy in type 2 diabetes.Galina, Smushkin, Adrian, Vellaopenaire +2 more sourcesIs the Recent Rise in Type 2 Diabetes Incidence From 1984 to 2007 Explained by the Trend in Increasing BMI? Evidence from a prospective study of British men [PDF]
, 2010 OBJECTIVE: To estimate the extent to which increasing BMI may explain the rise in type 2 diabetes incidence in British men from 1984 to 2007.RESEARCH DESIGN AND METHODS: A representative cohort ratio of 6,460 British men was followed-up for type 2 ...Morris, RW, Thomas, Mary C, Thomas, MC, Hardoon, Sarah L, Lennon, Lucy T, Whincup, Peter H, Whincup, PH, Hardoon, SL, Morris, Richard W, Wannamethee, S Goya, Lennon, LT, Wannamethee, SG +11 morecore +1 more sourceDiscovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes:rationale and design of the epidemiological studies within the IMI DIRECT Consortium [PDF]
, 2014 Aims/hypothesisThe DIRECT (Diabetes Research on Patient Stratification) Study is part of a European Union Framework 7 Innovative Medicines Initiative project, a joint undertaking between four industry and 21 academic partners throughout Europe.Rauh, S., Jablonka, B, Bernd Jablonka, Teare, Harriet J A, Frost, G.S., Ridderstråle, Martin, Herrgard, S., Hattersley, A, McDonald, T. J., Sanna Herrgård, Franks, Paul W., Bell, J., Cederberg, Henna, Hansen, TH, Andrea Mari, Pedersen, Oluf, Siloaho, Maritta, Mark Walker, Pearson, Ewan; id_orcid, Pearson, Ewan, Heymans, Martijn W., Perry, MH, Hansen, T.H., Rauh, S, Veikko Koivisto, Ridderstråle, Martin,, McDonald, T.J., Brunak, Søren, Cederberg, H., Barnett, A, Heymans, MartijnW., Frost, G, Vestergaard, H., Hattersley, Andrew T., Franks, P.W., Perry, Mandy, Laakso, M., Consortium, Direct, Paul W. Franks, Barnett, A., Heggie, A., Hansen, T., Thorand, Barbara, Heymans, MW, Siloaho, M., null null, Maritta Siloaho, Koivula, RW, Henrik Vestergaard, Hansen, Tue H., Alison Heggie, Lund University., Teare, Harriet J. A., Hansen, Tue H, Ewan Pearson, Ruetten, H, Hansen, T, Ramneek Gupta, Dekker, Jacqueline M, Rutters, Femke, Walker, M, Koopman, Anitra D, Tim J. McDonald, Barnett, Anna, Pearson, E, Koopman, AD, Koivula, R. W., Pearson, E., Koivula, Robert W., Heggie, Alison, McDonald, TJ, Koivula, Robert, Frost, G., Franks, PaulW., Rutters, F., Koopman, A. D., Perry, M.H., Heymans, M.W., Heggie, A, Ruetten, Hartmut, Simone Rauh, DIRECT Consortium (), Dekker, JM, Perry, MandyH., Hattersley, A., Koivula, R.W., Pearson, E. R., Franks, Paul, Herrgård, S, Franks, P. W., Vestergaard, H, Tue H. Hansen, Heymans, M. W., Koopman, AnitraD., Frost, Gary, Markku Laakso, Gary Frost, Gupta, Ramneek, Bell, J, Koopman, Anitra, Herrgård, Sanna, Teare, HJA, Dekker, Jacqueline M., Hattersley, Andrew, Hansen, Tue Haldor, Walker, M., Torben Hansen, Ridderstråle, M, Bell, Jimmy, Thorand, B, Brunak, S., Heymans, Martijn W, Søren Brunak, Laakso, M, Koopman, Anitra D., Koivisto, V., Mari, Andrea, Perry, Mandy H, Ridderstrale, M., Femke Rutters, Brunak, Soren, Pedersen, O., Hansen, Torben, Jacqueline M. Dekker, Perry, M. H., Gupta, R, Mari, A., Barbara Thorand, Teare, H. J. A., Koivisto, V, Mari, A, Dekker, JacquelineM., Koivula, RobertW., Walker, Mark, Oluf Pedersen, Franks, Paul,, Dekker, J.M., Siloaho, M, Ruetten, H., Cederberg, H, Koopman, A.D., Teare, HarrietJ.A., Pedersen, O, Dekker, J. M., Mandy H. Perry, Anitra D. Koopman, Martijn W. Heymans, Anna Barnett, Koivisto, Veikko, Laakso, Markku, Teare, H.J.A., Hansen, T. H., McDonald, TimJ., Henna Cederberg, Rauh, Simone, McDonald, Tim J, Gupta, R., Harriet J. A. Teare, Teare, H.J., Hartmut Ruetten, Jablonka, Bernd, Brunak, S, Bell, J.D., Andrew Hattersley, Franks, PW, Rutters, F, Vestergaard, Henrik, Hansen, T. V. O., Martin Ridderstråle, Robert W. Koivula, Thorand, B., Jablonka, B., Jimmy Bell, Koivula, Robert,, McDonald, Tim J., Perry, Mandy H., McDonald, Timothy J. +176 morecore +1 more sourceIncreased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin [PDF]
, 2010 OBJECTIVE The aim of this study was to investigate whether apolipoprotein B100 of LDL suffers increased damage by glycation, oxidation, and nitration in patients with type 2 diabetes, including patients receiving metformin therapy.Rabbani, Naila, D. Zehnder, A. Ceriello, P. J. Thornalley, N. Rabbani, Zehnder, Daniel, Chittari, Madhu Varma, C. W. Bodmer, Bodmer, Charles W., Ceriello, Antonio, M. V. Chittari, Thornalley, Paul J. +11 morecore +1 more sourceType-2 diabetes
Annals of Internal MedicineType 2 diabetes (T2D) is a prevalent disease that increases risk for vascular, renal, and neurologic complications. Prevention and treatment of T2D and its complications are paramount. Many advancements in T2D care have emerged over the past 5 years, including increased understanding of the importance of early intensive glycemic control, mental health, Skoradal, May-Britt, Andersen, Thomas Rostgaard, Mohr, Magni, Schmidt, Jakob Friis, Bangsbo, Jens +4 more +7 more sourcesBreast-Feeding and Childhood-Onset Type 1 Diabetes : A pooled analysis of individual participant data from 43 observational studies [PDF]
, 2012 OBJECTIVE To investigate if there is a reduced risk of type 1 diabetes in children breastfed or exclusively breastfed by performing a pooled analysis with adjustment for recognized confounders. RESEARCH DESIGN AND METHODS Relevant studies were identified Cinek, O., Joner, Geir, Brigis, G, Parslow, Roger C, Joner, Geir,, Geir Joner (8519850), Schober, E, Stene, Lars C, Radon, K, Carine E de Beaufort (16166561), Devoti, Gabriele, Karavanaki, K, Rosenbauer, Joachim,, Cardwell, Chris R, Ponsonby, Anne-Louise, Stene, Lars C., Stene, Lars C,, Memon, Anjum, Joner, G, Savilahti, E., Ionescu-Tirgoviste, C., C Patterson, Chris,, Urbonaite, B., Devoti, G., Patterson, Chris C., Constantin Ionescu-Tirgoviste (542793), Memon, A., Wadsworth, EJ, Urbonaite, Brone,, Patterson, Christopher, Strotmeyer, ES, Urbonaite, Brone, Chetwynd, Amanda,, Cardwell, Christopher; id_orcid, Lee-Ming Chuang (215892), Svensson, Jannet, Pozzilli, Paolo, Perez-Bravo, Francisco,, Wadsworth, Emma J.K., Chuang, Lee-Ming,, Brone Urbonaite (16166552), Benson, Victoria,, Gimeno, S.G., de Beaufort, Carine E, Pozzilli, P., DE BEAUFORT, Carine, Stene, LC, C Patterson, Chris, Radon, Katja, Karavanaki, Kyriaki,, Svensson, J., Goldacre, MJ, Michael J Goldacre (8832635), Katja Radon (487886), Goldacre, Michael J,, 莊立民, Goldacre, Michael J., Benson, V, Gimeno, Suely Godoy Agostinho [UNIFESP], Ludvigsson, Johnny, Joner, G., Paolo Pozzilli (310706), Savilahti, Erkki, Sipetic, Sandra,, Schober, E., Sipetic, Sandra, Rabiei, S, Brigis, Girts,, Anjum Memon (4461844), de Beaufort, Carine E,, Svensson, J, Cinek, Ondrej, Mona Salem (16166564), Chuang, Lee-Ming, Benson, V., Sandra Sipetic (16166558), Salem, Mona, Elsa S Strotmeyer (16166546), Perez-Bravo, Francisco, Patterson, CC, Strotmeyer, E.S., Karavanaki, K., Salem, Mona,, Brigis, G., Wadsworth, Emma J K,, Cardwell, CR, Perez-Bravo, F, Victoria Benson (6821780), Karavanaki, Kyriaki, Girts Brigis (4725450), Chetwynd, Amanda, Schober, Edith,, Roger C Parslow (9861266), Goldacre, M.J., Kyriaki Karavanaki (336472), Rabiei, Samira,, Ionescu-Tirgoviste, Constantin,, Rabiei, Samira, De Beaufort, Carine E., Sipetic, S, Cinek, O, Chuang, LM, Patterson, Chris C, Rosenbauer, Joachim, Schober, Edith, Chetwynd, A., Memon, A, Gimeno, SG, Ondrej Cinek (196591), Harrild, K., Ponsonby, Anne-Louise,, Svensson, Jannet,, Anne-Louise Ponsonby (340858), Chuang, Lee Ming, Beaufort, Carine E. de, Chris R Cardwell (5356490), Jannet Svensson (418468), Chetwynd, A, Ionescu-Tirgoviste, Constantin, Savilahti, Erkki,, Lars C Stene (16166537), Suely G Gimeno (16166540), Memon, Anjum,, Ponsonby, AL, Strotmeyer, Elsa S, Brigis, Girts, Rosenbauer, J., Chris C Patterson (5364881), Radon, Katja,, Parslow, RC, Wadsworth, EJK, Emma J K Wadsworth (16166543), Harrild, K, Parslow, R.C., Cardwell, Chris R., De Beaufort, CE, Ionescu-Tirgoviste, C, Cardwell, Chris R,, Devoti, G, Cardwell, C.R., Salem, M., Samira Rabiei (16166567), Cardwell, Chris R.;Stene, Lars C.;Ludvigsson, Johnny;Rosenbauer, Joachim;Cinek, Ondrej;Svensson, Jannet;Perez-Bravo, Francisco;Memon, Anjum;Gimeno, Suely G.;Wadsworth, Emma J. K.;Strotmeyer, Elsa S.;Goldacre, Michael J.;Radon, Katja;Chuang, Lee-Ming;Parslow, Roger C.;Chetwynd, Amanda;Karavanaki, Kyriaki;Brigis, Girts;Pozzilli, Paolo;Urbonaite, Brone;Schober, Edith;Devoti, Gabriele;Sipetic, Sandra;Joner, Geir;Ionescu-Tirgoviste, Constantin;de Beaufort, Carine E.;Harrild, Kirsten;Benson, Victoria;Savilahti, Erkki;Ponsonby, Anne-Louise;Salem, Mona;Rabiei, Samira;Patterson, Chris C., Edith Schober (640994), Wadsworth, Emma J. K., Cinek, Ondrej,, Ponsonby, A.L., Ponsonby, Anne Louise, Ludvigsson, J, Savilahti, E, Francisco Perez-Bravo (206402), Parslow, Roger C., Johnny Ludvigsson (167260), Benson, Victoria, Amanda Chetwynd (16166549), Wadsworth, Emma J K, Parslow, Roger C,, Ludvigsson, J., Sipetic, S., Rabiei, S., Stene, L.C., Rosenbauer, J, Pozzilli, P, Chuang, L.M., Erkki Savilahti (68955), Strotmeyer, Elsa S., Urbonaite, B, Wadsworth, E.J., Strotmeyer, Elsa S,, Devoti, Gabriele,, Ludvigsson, Johnny,, Goldacre, Michael, Joachim Rosenbauer (445335), Gimeno, Suely G, Perez-Bravo, F., Radon, K., Patterson, C.C., Pozzilli, Paolo,, Harrild, Kirsten, Gimeno, Suely G,, Salem, M, Goldacre, Michael J, Gimeno, Suely G., Harrild, Kirsten,, Kirsten Harrild (563534), Gabriele Devoti (16166555) +185 morecore +1 more source
