Results 41 to 50 of about 101,972,677 (301)
Type 2 diabetes
Journal of Physiotherapy, 2012 Adipose tissue plays a key role in the development of insulin resistance and its pathological sequelae, such as type 2 diabetes and non-alcoholic fatty liver disease. Dysfunction in the adipose tissue response to storing excess fatty acids as triglyceride can lead to adipose tissue inflammation and spillover of fatty acids from this tissue and ...openaire +4 more sourcesAssociation between BMI measured within a year after diagnosis of type 2 diabetes and mortality [PDF]
, 2013 OBJECTIVE: To describe the association of BMI with mortality in patients diagnosed with type 2 diabetes. RESEARCH DESIGN AND METHODS: Using records of 106,640 patients in Scotland, we investigated the association between BMI recorded around the diagnosis McKnight, J., Walker, Jeremy J., Morris, A., Sattar, N, Sattar, N., Wild, S., McKnight, J, Philip, Sam, Morris, Andrew, Wild, Sarah, Lindsay, R., Leese, Graham, Walker, JJ, Leese, G, McKnight, John, Group, Scottish Diabetes Research Network Epidemiology, Morris, A, Walker, J.J., Lindsay, Robert, Leese, G., Sattar, Naveed, Logue, J., Philip, S, Logue, J, Wild, Sarah; id_orcid, ?, ?, Logue, Jennifer, Walker, Jeremy J, Philip, S., Lindsay, R, Wild, S +30 morecore +1 more sourceMendelian randomization studies do not support a role for raised circulating triglyceride levels influencing type 2 diabetes, glucose levels, or insulin resistance. [PDF]
, 2011 OBJECTIVE: The causal nature of associations between circulating triglycerides, insulin resistance, and type 2 diabetes is unclear. We aimed to use Mendelian randomization to test the hypothesis that raised circulating triglyceride levels causally ...Gaunt, TR, Weedon, Michael N., De Silva, N. Maneka G., Weedon, MN, Luan, Jian'an, Harbord, Roger M., Harbord, Roger M, Ward, Kirsten J, Luan, J, Smith, GD, N. Maneka G. De Silva, Morris, Andrew D, Morris, Andrew D., Gaunt, Tom, Ebrahim, S, Ward, KJ, Claudia Langenberg, Knight, Beatrice A., Donnelly, Louise A, Beverley Shields, McCarthy, Mark I, Shah Ebrahim, De Silva, N. Maneka G, Palmer, Colin N A, Timothy M. Frayling, Ebrahim, Shah, Tom Gaunt, Debbie A. Lawlor, Rachel M. Freathy, Sandhu, MS, Ebrahim, Shah B J, Sandhu, Manjinder S., Hattersley, Andrew T., Harbord, RM, Beatrice A. Knight, Hattersley, Andrew T, Smith, George Davey, Palmer, Colin N. A., Knight, Beatrice A, Lawlor, DA, Louise A. Donnelly, Knight, BA, Langenberg, C, Freathy, RM, Roger M. Harbord, Freathy, Rachel M, Andrew T. Hattersley, Weedon, Michael N, Hattersley, AT, Palmer, CN, McCarthy, MI, Michael N. Weedon, Palmer, Tom M, Sandhu, Manjinder S, Palmer, CNA, Shields, B, Lawlor, Debbie A, Andrew D. Morris, Langenberg, Claudia, Shields, Beverley, De Silva, N Maneka G, Ward, Kirsten J., Mark I. McCarthy, Palmer, Colin NA, Donnelly, LA, De Silva, NM, Davey Smith, G, Frayling, Timothy M., Wareham, N, Tom M. Palmer, Gaunt, T, Nicholas Wareham, Morris, AD, Jian'an Luan, Lawlor, D, Manjinder S. Sandhu, Lawlor, Debbie A., Wareham, Nicholas, McCarthy, Mark I., Freathy, Rachel M., Palmer, TM, Frayling, Timothy M, Kirsten J. Ward, Donnelly, Louise A., George Davey Smith, Palmer, Tom M., De Silva, N M G, Colin N.A. Palmer, Frayling, TM, Palmer, Colin N. A.; id_orcid +89 morecore +1 more sourceCohort profile: the ‘Biomarkers of heterogeneity in type 1 diabetes’ study—a national prospective cohort study of clinical and metabolic phenotyping of individuals with long-standing type 1 diabetes in the Netherlands
BMJ OpenPurpose The ‘Biomarkers of heterogeneity in type 1 diabetes’ study cohort was set up to identify genetic, physiological and psychosocial factors explaining the observed heterogeneity in disease progression and the development of complications in people ... , Erwin Birnie, Giesje Nefs, Bruce H R Wolffenbuttel, Melanie M van der Klauw, Peter R van Dijk, Klaas Hoogenberg, Henk J Veeze, Henk-Jan Aanstoot, Bruce HR Wolffenbuttel, Charlotte E Vollenbrock, Pim Dekker, Lianne S M Boesten, Martine M C de Vries-Velraeds, Adriaan Kooy, Dick Mul, Sanjoy Dutta, Rita D M Varkevisser, Michael P Brugts, Petronella H L M Duijvestijn, Christine Fransman, Rob K Gonera, Esther Latres, Sandra Loves, Theo Sas, Marleen J Vosjan-Noeverman, Rita DM Varkevisser, Lianne SM Boesten, Peter R van Dijk, Petronella HLM Duijvestijn, Martine MC de Vries-Velraeds, Melanie M van der Klauw +31 moredoaj +1 more sourceCircadian gene variants and susceptibility to type 2 diabetes : a pilot study [PDF]
, 2012 Background
Disruption of endogenous circadian rhythms has been shown to increase the risk of developing type 2 diabetes, suggesting that circadian genes might play a role in determining disease susceptibility.O’Hare J. Paul, Shahrad Taheri (57360), M. Ann Kelly (174447), Shera, A. Samad, Hydrie MZ, Barnett, Anthony H., Taheri, S., Anthony H Barnett, Kumar S, Shera, A.S., Rees, Simon D., Kelly, M. Ann, Kelly, Marilyn, Shera, AS, Raychaudhuri, Soumya, Sudhesh Kumar (89490), Abdul Basit (174463), Bellary, Srikanth, Rees, S.D., Kumar, S., Barnett AH, J Paul O'Hare, M. Zafar I. Hydrie (174450), Basit, A., Bellary Srikanth, O'Hare, JP, Bellary S, Shera, A Samad, Taheri S, DIAGRAM Consortium, Hydrie, MZ, Taheri, Shahrad, M Zafar I Hydrie, Bellary, S., Abdul Basit, Hydrie M. Zafar I., Shera A. Samad, Barnett, Anthony, Bellary, S, Basit Abdul, Basit, A, Rees SD, Kumar Sudhesh, Srikanth Bellary (89487), Rees, Simon D, Sudhesh Kumar, Shahrad Taheri, O'Hare, J Paul, Rees, Simon, Kelly, M Ann, SAT2D Consortium, Hydrie, M.Z.I., Kelly MA, A Samad Shera, Basit, Abdul, Barnett, A.H., Anthony H. Barnett (174467), Rees Simon D., Kelly, M.A., Srikanth Bellary, Shera AS, Basit A, Hydrie, M Zafar I, Hydriem, Zafar L., Kumar, Sudhesh, Barnett, Anthony H, O'Hare, J.P., Kelly M. Ann, Hydrie, M. Zafar I., Simon D Rees, Kumar, S, A. Samad Shera (174452), O'Hare, J. Paul, Taheri Shahrad, Barnett Anthony H., J. Paul O’Hare (174457), M Ann Kelly, Simon D. Rees (174448) +77 morecore +1 more source“We Cannot Talk as a Family”: Complexities of Survivorship Communication Among Hispanic/Latino Young Adult Survivors of Childhood Cancer, Parents, and Clinicians
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background
Young adult childhood cancer survivors (YA‐CCS) have an increased risk of treatment‐related health complications throughout their lives. Lifelong survivorship care is recommended, yet many YA‐CCS experience disruptions in care during pediatric‐to‐adult transitions and do not receive recommended survivorship care.Kevin Shanchen Pu, Nicole Fernández‐Viña, Briana C. Martin‐Villa, Daniela Ramirez, Rebecca M. Lewinsohn, Mary Smith, Heidi Boynton, Lidia Schapira, Stephanie M. Smith +8 morewiley +1 more sourceCarnitine and type 2 diabetes [PDF]
Diabetes/Metabolism Research and Reviews, 2009 AbstractStudies in humans and animals demonstrate that “lipid over supply” causes or worsens insulin resistance via multiple mechanisms involving the accumulation of intracellular lipids in multiple tissues. In particular, the accumulation of fatty acyl CoA derivatives/metabolites in muscle inhibits both insulin signaling and glucose oxidation ...openaire +2 more sourcesExperience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction
This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods
Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto +9 morewiley +1 more sourceDiabetic retinopathy at diagnosis of type 2 diabetes in Scotland [PDF]
, 2012 The prevalence of retinopathy at first screening is lower than in previous UK studies, consistent with earlier diagnosis of diabetes. Most newly diagnosed type 2 diabetic patients in Scotland are screened within an acceptable interval and the prevalence ...Lee, N, Colhoun, H.M., H. C. Looker, Colhoun, H. M., M. Black, Sattar, N, Olson, J.A., Morris, A D, Olson, J. A., Philip, Sam, J. A. Olson, S. H. Wild, Olson, J A, Black, M., S. O. Nyangoma, Leese, G P, Doig, J, H. M. Colhoun, Looker, H C, Doig, J., ?, ?, J. A. McKnight, Nyangoma, S. O., Lindsay, R. S., null null, Nyangoma, S O, Lindsay, R S, Colhoun, H M, McKnight, J A, Leese, G.P., Black, M, Wild, S H, D. Cromie, Sattar, N., Cromie, D., Wild, S.H., A. D. Morris, Scottish Diabetic Retinopathy Screening Collaborative, McKnight, J. A., Morris, A.D., Lindsay, R.S., Leese, G. P., Morris, Andrew, Lee, N., G. P. Leese, N. Sattar, N. Lee, Cromie, D, Wild, S. H.; id_orcid, Looker, H. C., R. S. Lindsay, McKnight, J.A., J. Doig, Nyangoma, S.O., Philip, S., S. Philip, Looker, H.C. +56 morecore +1 more source