Results 121 to 130 of about 1,619,048 (311)
Transmission factors and exposure to infections at work and invasive pneumococcal disease
Abstract Background Working in close contacts with coworkers or the general public may be associated with transmission of invasive pneumococcal disease (IPD). We investigated whether crowded workplaces, sharing surfaces, and exposure to infections were factors associated with IPD.
Kjell Torén+4 more
wiley +1 more source
Local Interpretability of Calibrated Prediction Models: A Case of Type 2 Diabetes Mellitus Screening Test [PDF]
Machine Learning (ML) models are often complex and difficult to interpret due to their 'black-box' characteristics. Interpretability of a ML model is usually defined as the degree to which a human can understand the cause of decisions reached by a ML model. Interpretability is of extremely high importance in many fields of healthcare due to high levels
arxiv
Hubungan Stres dengan Kualitas Hidup Penderita Diabetes Mellitus Tipe 2 [PDF]
Diabetes mellitus is a diasease who will be happen on a life time. The changes in lifestyle, medication and treatment who must be followed is a cause stress the patient type 2 diabetes mellitus.
', H. (Herlina)+2 more
core
Neuropsychiatric screening in type 2 diabetes mellitus
Diabetes mellitus is considered to be one of the most psychologically demanding of the chronic medical illnesses and is often associated with several psychiatric disorders.
Sunil K Kota+5 more
doaj +1 more source
Background: Diabetic complications are related to impaired glycemic control. The UK Prospective Diabetes Study (UKPDS) showed that metformin therapy in overweight and obese patients with type 2 diabetes mellitus (T2DM) could reduce HbA1c and complications.
Masood Javed+2 more
openaire +2 more sources
Embelin cotargets SHP2 to disrupt the SHP2/GRB2/SOS complex, inhibiting cancer‐related signaling pathways such as MAPK, (PI3K)/AKT pathway, and XIAP to induce apoptosis signaling pathway, respectively, leading to synthetic lethality in KRAS‐mutant NSCLC cells both in vivo and in vitro.
Nai‐jie Fu+8 more
wiley +1 more source
Khat Chewing and Type 2 Diabetes Mellitus
Mohammed Badedi,1 Hussain Darraj,1 Abdulrahman Hummadi,1 Abdullah Najmi,2 Yahiya Solan,1 Ibrahim Zakry,1 Abdullah Khawaji,1 Sayedah Zaylai,1 Norah Rajeh,1 Hassan Alhafaf,1 Wali Hakami,1 Awaji Bakkari,1 Maryam Kriry,1 Abdulraheem Dagreri,1 Ebrahim Haddad1
Badedi M+14 more
doaj
By studying the maturation mechanisms of vasopressin (AVP), this manuscript identifies FAM134B‐mediated ER‐phagy as a critical pathway for degrading both aggregated proAVP and the key ERAD component, HRD1. HRD1 induction mitigates proAVP aggregation and support AVP neuron function in the absence of autophagy.
Xuya Pan+16 more
wiley +1 more source
Tirzepatide, a dual GIP/GLP‐1 receptor agonist for diabetes, suppresses colorectal cancer growth by targeting glucose metabolism. It inhibits cancer cell proliferation, promotes apoptosis, and induces tumor regression. It reduces glucose uptake and destabilizes HIF‐1α for degradation to downregulate PFKFB3/PFK‐1 enzymes, thus contributing to the ...
Yikai Zhang+11 more
wiley +1 more source
The implementation of guidelines in a South African population with type 2 diabetes [PDF]
Objective: The aim of this study was to identify the treatment gaps that pertain to risk factors in South African patients with type 2 diabetes mellitus, using national treatment guidelines.Design: Cross-sectional study.Setting and subjects: The study ...
Butkow, W+3 more
core +1 more source