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The bioenergetics of inflammation: insights into obesity and type 2 diabetes

European Journal of Clinical Nutrition, 2017
Diabetes mellitus is one of the most common chronic metabolic disorders worldwide, and its incidence in Asian countries is alarmingly high. Type 2 diabetes (T2DM) is closely associated with obesity, and the staggering rise in obesity is one of the primary factors related to the increased frequency of T2DM.
Keane, Kevin   +4 more
openaire   +3 more sources

The Evil Axis of Obesity, Inflammation and Type-2 Diabetes

Endocrine, Metabolic & Immune Disorders - Drug Targets, 2011
Obesity and type 2 diabetes (T2D) are global problems affecting all age groups and have been characterized as lifestyle disorders. Though no study has clearly proved a direct correlation between obesity and T2D, a number of factors are associated with obesity causing insulin resistance and T2D.
Arghya, Das, Sangita, Mukhopadhyay
openaire   +2 more sources

Targeting inflammation to reduce ASCVD in type 2 diabetes

Journal of Diabetes and its Complications, 2019
ASCVD is the leading cause of mortality in T2DM. Inflammation appears to be pivotal in the genesis of ASCVD. As T2DM is also a pro-inflammatory state, our aim was to determine the benefit of anti-inflammatory strategies on ASCVD in T2DM. PubMed searches were conducted using the keywords of T2DM, ASCVD, Inflammation and clinical trials.
Ishwarlal, Jialal, Ajay, Chaudhuri
openaire   +2 more sources

Partial suppression of type 2 inflammation with mepolizumab

The Journal of Allergy and Clinical Immunology: In Practice, 2022
Kirsten E. Stewart   +3 more
openaire   +3 more sources

Type 2 Diabetes and Islet Inflammation

2013
Type 2 diabetes occurs when the pancreatic islet β-cell fails to adapt to the increased insulin demand caused by obesity-associated insulin resistance.
openaire   +1 more source

Inflammation and aging: signaling pathways and intervention therapies

Signal Transduction and Targeted Therapy, 2023
Pengxu Qian
exaly  

Type 2 diabetes and inflammation.

2012
J. Lieffers   +5 more
openaire   +1 more source

Targeting protein phosphatases for the treatment of inflammation-related diseases: From signaling to therapy

Signal Transduction and Targeted Therapy, 2022
Yang Sun, Qiang Xu, Yang Sun
exaly  

Inflammation and type 2 diabetes

The Biomedical & Life Sciences Collection, 2013
openaire   +1 more source

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