Results 241 to 250 of about 102,290,503 (289)

Type 2 inflammation in chronic obstructive pulmonary disease: A promising treatable trait and practice recommendations. [PDF]

Chin Med J Pulm Crit Care Med
Chen Y, Yang T, Zhang J, Chen X, Chen X, Cheng Z, Li Y, Fan X, Han W, He Z, Ma D, Meng Y, Yan J, Yin Y, Zeng H, Zhou Q, Zhou X, Cai H, Cui Y, Ma Y, Wen F, Sun Y, Sun D, Liu X, Zheng J, Wang W, Zheng Z, Yan X, Cai S, Cao J, Song Y, Zhao J, Zhou Y, Zhu H, Li M, Guo Y, Ma Q, Liang Z, Zhao L, Chen Y, Wang J, Wang F, Yang Y, Yang H, Kang J, Chen R, Assembly of Chronic Obstructive Pulmonary Disease (COPD) of Chinese Thoracic Society (CTS), COPD Working Group of Chinese Association of Chest Physician (CACP) of the Chinese Medical Doctor Association, Evidence-Based Medicine Group of the Clinical Epidemiology Branch of the Chinese Medical Association, Respiratory Disease Control Committee of the Chinese Preventive Medicine Association, Precision Medicine Group of the Respiratory Disease Committee of the Cross-Strait Medical and Health Exchange Association.   +50 more
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CM512, a potentially novel IgG1-based bispecific antibody dual-targeting TSLP and IL-13, for the suppression of type 2 inflammation. [PDF]

J Transl Med
Yang Y, Lan Y, Bian L, Li Y, Song Q, Gao X, Hou Q, Bai Y, Chen B.   +8 more
europepmc   +1 more source

The Global Airways in Practice: Long-term Effects of Mepolizumab With or Without FESS on Type 2 Inflammation in Patients With CRSwNP. [PDF]

Int Forum Allergy Rhinol
Tidemandsen J, Backer V, Homøe AS, Jensen THL, Aanæs K, Meteran H, Hostrup M, Moesgaard L, Haase C, Gibson PG.   +9 more
europepmc   +1 more source

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Inflammation and type 2 diabetes

Diabetes & Metabolism, 2012
Low-grade inflammation is a common feature in subjects with type 2 diabetes (T2D). Heart disease, the metabolic syndrome and T2D all have in common the increased concentration of circulatory cytokines as a result of inflammation. Inflammatory cytokines are produced by different cell types and secreted into the circulation, where they regulate different
M C, Calle, M L, Fernandez
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The emerging role of type 2 inflammation in asthma

Expert Review of Clinical Immunology, 2020
Introduction: Bronchial asthma (BA) is a chronic airways inflammatory disease. Based on the biological mechanisms that underline the disease, asthma has been classified as type 2 or non-type 2 phenotype.Areas covered: An emerging role has been identified for group 2 innate lymphoid cells (ILC2s) able to produce the classical type 2 cytokines.
Andrea Matucci, Susanna Bormioli, Francesca Nencini, Enrico Maggi, Alessandra Vultaggio   +4 more
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Autoimmune responses and inflammation in type 2 diabetes

Journal of Leukocyte Biology, 2020
Abstract Obesity-induced insulin resistance is one of the largest noncommunicable disease epidemics that we are facing at the moment. Changes in lifestyle and greater availability of low nutritional value, high caloric food has led to the highest rates of obesity in history.
Mukul Prasad, Elijah W. Chen, Sue-Anne Toh, Nicholas R. J. Gascoigne   +3 more
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Inflammation and Type 2 Diabetes

2017
This chapter discusses the current insights into how inflammation, particularly obesity-associated low-grade inflammation, may contribute to development of insulin resistance and β-cell failure, and hence comprise a major culprit for the development of type 2 diabetes. For development of type 2 diabetes, at least two major events are necessary. First,
Van Greevenbroek, Marleen M.J., Schalkwijk, Casper G., Stehouwer, Coen D.A.   +2 more
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Macrophages and islet inflammation in type 2 diabetes

Diabetes, Obesity and Metabolism, 2013
Type 2 diabetes ( T2D ) is characterized by insulin resistance and impaired insulin secretion from pancreatic β‐cells. Inflammatory cytokines, including tumour necrosis factor‐α ( TNF ‐α), have been shown to promote insulin resistance, and altered ...
K, Eguchi, I, Manabe
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Mast cells: The Janus of type 2 inflammation

Immunity
Mast cells (MCs) are effectors in type 2 immunity, well known for their detrimental roles in allergy. In this issue of Immunity, Alhallak et al. now identify a protective role of MCs against exacerbated immune responses mediated by prostaglandin E2 (PGE2)-driven soluble ST2.
Johanna, Kotrba, Anne, Dudeck
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Islet Inflammation in Type 2 Diabetes

Diabetes Care, 2008
Decreases in both mass and secretory function of insulin-producing β-cells contribute to the pathophysiology of type 2 diabetes. The histology of islets from patients with type 2 diabetes displays an inflammatory process characterized by the presence of cytokines, apoptotic cells, immune cell infiltration, amyloid deposits, and eventually fibrosis ...
Marc Y. Donath, Desiree M. Schumann, Mirjam Faulenbach, Helga Ellingsgaard, Aurel Perren, Jan A. Ehses   +5 more
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