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In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin +12 more
wiley +1 more source
Reply to Melhorn and Couillard: Baseline Membrane Thickness in Asthma: Where Type-2 Inflammation Meets Remodeling? [PDF]
Leung C, Fahy JV.
europepmc +1 more source
Type 2 inflammation in COPD: is it just asthma? [PDF]
Beech A +5 more
europepmc +1 more source
Type 2 inflammation accelerates CD4<sup>+</sup> T-cell senescence in asthma. [PDF]
Liu H, Li Z, Sun Y, Aili A, Chang C.
europepmc +1 more source
Targeting type-2 inflammation in pulmonary hypertension: lessons from a novel model. [PDF]
Singh N, Oldham WM.
europepmc +1 more source
Type 2 airway inflammation in COPD
Globally, nearly 400 million persons have COPD, and COPD is one of the leading causes of hospitalisation and mortality across the world. While it has been long-recognised that COPD is an inflammatory lung disease, dissimilar to asthma, type 2 inflammation was thought to play a minor role.
Francesca, Polverino, Don D, Sin
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Regulation of type 2 inflammation by type I interferons [PDF]
Rhinovirus-induced asthma exacerbations are a major cause of morbidity and mortality in patients. Experimental clinical infection studies indicate rhinovirus augments type 2 inflammation in asthma. Additionally, asthmatic lung cells have impaired type I interferon production in response to rhinovirus stimulation. Evidence suggests co-regulation of type
Ching, Yee-Man
openaire +3 more sources
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Inflammation and type 2 diabetes
Diabetes & Metabolism, 2012Low-grade inflammation is a common feature in subjects with type 2 diabetes (T2D). Heart disease, the metabolic syndrome and T2D all have in common the increased concentration of circulatory cytokines as a result of inflammation. Inflammatory cytokines are produced by different cell types and secreted into the circulation, where they regulate different
M C, Calle, M L, Fernandez
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The emerging role of type 2 inflammation in asthma
Expert Review of Clinical Immunology, 2020Introduction: Bronchial asthma (BA) is a chronic airways inflammatory disease. Based on the biological mechanisms that underline the disease, asthma has been classified as type 2 or non-type 2 phenotype.Areas covered: An emerging role has been identified for group 2 innate lymphoid cells (ILC2s) able to produce the classical type 2 cytokines.
Andrea Matucci +4 more
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Resolution of Inflammation in Type 2 Diabetes
Type 2 diabetes, ERV-1 receptor, phagocytosis, chronic inflammation, resolution.
Freire, Marcelo
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