Results 231 to 240 of about 102,290,503 (289)

Clinical Disease Burden in Patients with Chronic Obstructive Pulmonary Disease and Type 2 Inflammation in Japan: A Retrospective Database Analysis (EUROS Study). [PDF]

Int J Chron Obstruct Pulmon Dis
Muro S, Orimo M, Sunaga Y, Inokuchi S, Tokuda M, Ishida M.   +5 more
europepmc   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Nasal Cytology as a Cellular Window into Epithelial Dysfunction and Type 2 Inflammation: From Mechanisms to Translational Implications. [PDF]

Cells
Gelardi M.
europepmc   +1 more source

Vascular normalization confers an endothelial immune suppressive gene expression profile

Molecular Oncology, EarlyView.
We compare the immunoregulatory gene expression profiles of healthy endothelial cells or endothelial cells from tumors having a normalized endothelium (low leakage) with that of wild‐type tumors (high leakage) and observe that the wild‐type tumor endothelium exhibits immunostimulatory properties.
Liqun He, Michael Welsh
wiley   +1 more source

Mef2d: a novel transcription factor in type 2 allergic lung inflammation

Signal Transduction and Targeted Therapy
Laura Surace, Christoph Wilhelm, Christian Bode   +2 more
doaj   +1 more source

Baseline Membrane Thickness in Asthma: Where Type-2 Inflammation Meets Remodeling? [PDF]

Am J Respir Crit Care Med
Melhorn J, Couillard S.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Inhibition of Airway Epithelial CTSC Attenuates Type 2 Inflammation: Implications for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps. [PDF]

J Inflamm Res
Li X, Zhu Z, Zhu J, Lin B, Zhou S, Yang R, Liu Y, Peng Y, Qiu Q.   +8 more
europepmc   +1 more source

IL-4/IL-13-Driven Dysregulation of Epidermal Lipid Metabolism in Atopic Dermatitis: An Immunometabolic Link Between Type 2 Inflammation and Barrier Dysfunction. [PDF]

Cells
Andrzejczak K, Sternak A, Witkowski W, Flak A, Maj J, Ponikowska M.   +5 more
europepmc   +1 more source

The AIM4 Next Step study: Comparing inhaled corticosteroid dose escalation to dupilumab in patients with uncontrolled asthma and type 2 inflammation. [PDF]

J Allergy Clin Immunol Glob
Busse WW, Iammatteo M, Soliman M, Lugogo NL, Bacharier LB, O'Byrne PM, Bourdin A, Katial RK, Mosnaim GS, Peters AT, Korn S, Xia C, Ledanois O, Martin A, Sacks HJ, Deniz Y.   +15 more
europepmc   +1 more source