Results 221 to 230 of about 1,471,209 (258)

Inflammation, diet, and type 2 diabetes: a mini-review

Journal of Immunoassay and Immunochemistry, 2020
Inflammation is a common feature of type 2 diabetes (T2D). Inflammatory cytokines increase in patients with type 2 diabetes, metabolic syndrome, and heart disease. Various types of cells can produce inflammatory cytokines and then release them into the bloodstream, where their complex interactions with target tissues raise a tissue-specific immune ...
Simin Jafaripour, Sima Sedighi, Mohammad Hassan Jokar, Mehrdad Aghaei, Maliheh Moradzadeh   +4 more
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Osteoprotegerin and biomarkers of vascular inflammation in type 2 diabetes

Diabetes/Metabolism Research and Reviews, 2010
AbstractBackgroundOsteoprotegerin (OPG), receptor activator for nuclear factor kappa beta ligand (RANKL) and tumour necrosis factor–related apoptosis‐inducing ligand (TRAIL) are newly discovered members of the tumour necrosis factor‐alpha receptor superfamily.
O'Sullivan, Eoin P, Ashley, David T, Davenport, Colin, Devlin, Niamh, Crowley, Rachel, Agha, Amar, Thompson, Christopher J, O'Gorman, Donal, Smith, Diarmuid   +8 more
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The Role of Type 2 Inflammation in the Pathogenesis of Asthma Exacerbations

Annals of the American Thoracic Society, 2015
Abstract Asthma exacerbations are an important cause of asthma morbidity. Although viral infection of the upper airway is a common cause of asthma exacerbations, the reasons why some patients with asthma are exacerbation prone and others are exacerbation resistant are not fully understood.
Eleanor M, Dunican, John V, Fahy
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Targeting inflammation to reduce ASCVD in type 2 diabetes

Journal of Diabetes and its Complications, 2019
ASCVD is the leading cause of mortality in T2DM. Inflammation appears to be pivotal in the genesis of ASCVD. As T2DM is also a pro-inflammatory state, our aim was to determine the benefit of anti-inflammatory strategies on ASCVD in T2DM. PubMed searches were conducted using the keywords of T2DM, ASCVD, Inflammation and clinical trials.
Ishwarlal, Jialal, Ajay, Chaudhuri
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The linkage between inflammation and Type 2 diabetes mellitus

Diabetes Research and Clinical Practice, 2013
The Type 2 diabetes mellitus (DM2) is considered nowadays as one of the most important chronic disturbances because of the significant number of people with diabetes and its severe complications, responsible for elevated indexes of morbidity and mortality.
Nathália G, Cruz, Lirlândia P, Sousa, Marinez O, Sousa, Nathalia T, Pietrani, Ana P, Fernandes, Karina B, Gomes   +5 more
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The bioenergetics of inflammation: insights into obesity and type 2 diabetes

European Journal of Clinical Nutrition, 2017
Diabetes mellitus is one of the most common chronic metabolic disorders worldwide, and its incidence in Asian countries is alarmingly high. Type 2 diabetes (T2DM) is closely associated with obesity, and the staggering rise in obesity is one of the primary factors related to the increased frequency of T2DM.
Keane, Kevin, Calton, E., Carlessi, Rodrigo, Hart, P., Newsholme, Philip   +4 more
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The Evil Axis of Obesity, Inflammation and Type-2 Diabetes

Endocrine, Metabolic & Immune Disorders - Drug Targets, 2011
Obesity and type 2 diabetes (T2D) are global problems affecting all age groups and have been characterized as lifestyle disorders. Though no study has clearly proved a direct correlation between obesity and T2D, a number of factors are associated with obesity causing insulin resistance and T2D.
Arghya, Das, Sangita, Mukhopadhyay
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Type 2 Diabetes and Islet Inflammation

2013
Type 2 diabetes occurs when the pancreatic islet β-cell fails to adapt to the increased insulin demand caused by obesity-associated insulin resistance.
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Partial suppression of type 2 inflammation with mepolizumab

The Journal of Allergy and Clinical Immunology: In Practice, 2022
Kirsten E. Stewart, Rory Chan, Rasads Misirovs, Brian J. Lipworth   +3 more
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Regulation of type 2 inflammation by type I interferons

2016
Rhinovirus-induced asthma exacerbations are a major cause of morbidity and mortality in patients. Experimental clinical infection studies indicate rhinovirus augments type 2 inflammation in asthma. Additionally, asthmatic lung cells have impaired type I interferon production in response to rhinovirus stimulation. Evidence suggests co-regulation of type
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