Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching +9 more
wiley +1 more source
Signal peptides for engineered protein secretion by free and hydrogel-encapsulated cyanobacteria. [PDF]
Soulier NT +5 more
europepmc +1 more source
Information Transmission Strategies for Self‐Organized Robotic Aggregation
In this review, we discuss how information transmission influences the neighbor‐based self‐organized aggregation of swarm robots. We focus specifically on local interactions regarding information transfer and categorize previous studies based on the functions of the information exchanged.
Shu Leng +5 more
wiley +1 more source
Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang +11 more
wiley +1 more source
High-Level Constitutive Secretory Expression and Low-Temperature Adaptation Engineering of the Acid Protease RMAP9 from the Mangrove-Derived Yeast <i>Rhodotorula mucilaginosa</i>. [PDF]
Zhang Y +6 more
europepmc +1 more source
Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley +1 more source
Type III Secretion System Genotypes and Biofilm-Forming Capacity of <i>Pseudomonas aeruginosa</i> Bloodstream Isolates: An Exploratory Analysis of the <i>exoU</i>-Fluoroquinolone Association. [PDF]
Malaş İren H, Mete E.
europepmc +1 more source
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
Role of Triceps Muscle Fiber-Specific Myokines in Pancreatic β-Cell Protection: Implications for Type 2 Diabetes: A Narrative Review. [PDF]
Tague C, Makeda D, Yokolo H, Ekouo J.
europepmc +1 more source
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen +20 more
wiley +1 more source

