Results 1 to 10 of about 1,849,986 (263)
Toward Plant Single Cell Type Systems Biology [PDF]
Frontiers in Plant Science, 2016 The molecular responses of a plant to a stress and the molecular profiles of plant organs during their development and differentiation are the reflection of the contribution from different cell types composing the plant and the organs. Hence, a major limitation to understanding plant cellular and molecular responses in different cells is the ...
Marc eLibault, Sixue eChen
doaj +4 more sources
Type VI Secretion Effectors: Methodologies and Biology [PDF]
Frontiers in Cellular and Infection Microbiology, 2017 The type VI secretion system (T6SS) is a nanomachine deployed by many Gram-negative bacteria as a weapon against eukaryotic hosts or prokaryotic competitors.
Yun-Wei Lien +3 more
doaj +3 more sources
Macroscopic Quantum-Type Potentials in Theoretical Systems Biology [PDF]
Cells, 2013 We review in this paper the use of the theory of scale relativity and fractal space-time as a tool particularly well adapted to the possible development of a future genuine systems theoretical biology.
Laurent Nottale
doaj +3 more sources
Antibiotics targeting bacterial protein synthesis reduce the lytic activity of bacteriophages
Virus Research, 2022 Combination therapy of bacteriophages and antibiotics requires careful selection of specific antibiotics as it is crucial towards determining the success of phage therapy to treat multiple drug-resistant bacterial infections.
Medhavi Vashisth +5 more
doaj +1 more source
Scientific Reports, 2023 A rod-shaped, motile, Gram-negative bacterial strain named DM-R-R2A-13T was isolated from the plant Cannabis sativa L. ‘Cheungsam’. The phylogenetic analysis of the 16S rRNA gene sequence revealed that strain DM-R-R2A-13T belongs to the family ...
Doeun Jeon +8 more
doaj +1 more source
mSystems, 2019 The release of synthetic chemical pollutants in the environment is posing serious health risks. Enzymes, including oxygenases, play a crucial role in xenobiotic degradation. In the present study, we employed a functional metagenomics approach to overcome
Chandni Sidhu +3 more
doaj +3 more sources
Nutritional systems biology of type 2 diabetes [PDF]
Genes & Nutrition, 2015 Type 2 diabetes (T2D) has become an increasingly challenging health burden due to its high morbidity, mortality, and heightened prevalence worldwide. Although dietary and nutritional imbalances have long been recognized as key risk factors for T2D, the underlying mechanisms remain unclear. The advent of nutritional systems biology, a field that aims to
Zhao, Yuqi +2 more
openaire +4 more sources
The integrative biology of type 2 diabetes [PDF]
Nature, 2019 Obesity and type 2 diabetes are the most frequent metabolic disorders, but their causes remain largely unclear. Insulin resistance, the common underlying abnormality, results from imbalance between energy intake and expenditure favouring nutrient-storage pathways, which evolved to maximize energy utilization and preserve adequate substrate supply to ...
Michael, Roden, Gerald I, Shulman
openaire +2 more sources
The cell repair research for Parkinson’s disease: A systematic review
Journal of Neurorestoratology, 2020 Background and Objective:Parkinson’s disease (PD) is a common neurodegenerative disease. Previous studies have demonstrated the effect of cell-based therapies, but their clinical efficacy and safety have not been evaluated.
Chao Chen +7 more
doaj +1 more source
Structural biology of type VI secretion systems [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2012 Type VI secretion systems (T6SSs) are transenvelope complexes specialized in the transport of proteins or domains directly into target cells. These systems are versatile as they can target either eukaryotic host cells and therefore modulate the bacteria–host interaction and pathogenesis or bacterial cells and therefore facilitate access to a specific ...
Cascales, E., Cambillau, Christian
openaire +5 more sources