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Type VI Secretion Effectors: Methodologies and Biology
The type VI secretion system (T6SS) is a nanomachine deployed by many Gram-negative bacteria as a weapon against eukaryotic hosts or prokaryotic competitors.
Yun-Wei Lien +3 more
doaj +2 more sources
Macroscopic Quantum-Type Potentials in Theoretical Systems Biology [PDF]
We review in this paper the use of the theory of scale relativity and fractal space-time as a tool particularly well adapted to the possible development of a future genuine systems theoretical biology.
Laurent Nottale
doaj +2 more sources
Single-cell network biology enabling cell-type-resolved disease genetics [PDF]
Gene network models provide a foundation for graph theory approaches, aiding in the novel discovery of drug targets, disease genes, and genetic mechanisms for various biological functions.
Junha Cha, Insuk Lee
doaj +2 more sources
Unique somatic and malignant expression patterns implicate PIWI-interacting RNAs in cancer-type specific biology [PDF]
Human PIWI-interacting RNAs (piRNAs) are known to be expressed in germline cells, functionally silencing LINEs and SINEs. Their expression patterns in somatic tissues are largely uncharted.
Victor D. Martinez +9 more
semanticscholar +2 more sources
Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis [PDF]
Human T lymphotropic viruses (HTLVs) are complex deltaretroviruses that do not contain a proto-oncogene in their genome, yet are capable of transforming primary T lymphocytes both in vitro and in vivo.
Patrick L. Green, Priya Kannian
doaj +2 more sources
Islet biology, the CDKN2A/B locus and type 2 diabetes risk [PDF]
Yahui Kong +3 more
semanticscholar +2 more sources
Antibiotics targeting bacterial protein synthesis reduce the lytic activity of bacteriophages
Combination therapy of bacteriophages and antibiotics requires careful selection of specific antibiotics as it is crucial towards determining the success of phage therapy to treat multiple drug-resistant bacterial infections.
Medhavi Vashisth +5 more
doaj +1 more source
The biology, function, and biomedical applications of exosomes
Clinical uses of cellular communication Exosomes are a type of extracellular vesicle that contain constituents (protein, DNA, and RNA) of the cells that secrete them.
R. Kalluri, Valerie S. LeBleu
semanticscholar +1 more source
A rod-shaped, motile, Gram-negative bacterial strain named DM-R-R2A-13T was isolated from the plant Cannabis sativa L. ‘Cheungsam’. The phylogenetic analysis of the 16S rRNA gene sequence revealed that strain DM-R-R2A-13T belongs to the family ...
Doeun Jeon +8 more
doaj +1 more source
Gastric cancer with radiographically occult metastatic disease: Biology, challenges, and diagnostic approaches [PDF]
Gastric adenocarcinoma is an aggressive cancer that demonstrates heterogeneous biology depending on patient ethnicity, tumor location, tumor type, and genetic profile.
Fangman, Benjamin +3 more
core +2 more sources

