Results 11 to 20 of about 14,138,795 (349)

Structural biology of Type IV secretion system [PDF]

open access: bronzeActa Crystallographica Section A Foundations of Crystallography, 2005
C. Oomen   +4 more
openaire   +3 more sources

The role of various collagen types in tumor biology: a review

open access: goldFrontiers in Oncology
Collagen comprises approximately 30% of the body’s protein content and is essential for maintaining the structural integrity, support, and strength of the skin, muscles, bones, and connective tissues. Recent research has further elucidated its role in various aspects of tumor biology, including tumorigenesis, invasion, migration, drug resistance, and ...
Yuchuan Zhou   +3 more
openaire   +4 more sources

Antibiotics targeting bacterial protein synthesis reduce the lytic activity of bacteriophages

open access: yesVirus Research, 2022
Combination therapy of bacteriophages and antibiotics requires careful selection of specific antibiotics as it is crucial towards determining the success of phage therapy to treat multiple drug-resistant bacterial infections.
Medhavi Vashisth   +5 more
doaj   +1 more source

Bioplastic (poly-3-hydroxybutyrate)-producing Massilia endophytica sp. nov., isolated from Cannabis sativa L. ‘Cheungsam’

open access: yesScientific Reports, 2023
A rod-shaped, motile, Gram-negative bacterial strain named DM-R-R2A-13T was isolated from the plant Cannabis sativa L. ‘Cheungsam’. The phylogenetic analysis of the 16S rRNA gene sequence revealed that strain DM-R-R2A-13T belongs to the family ...
Doeun Jeon   +8 more
doaj   +1 more source

The biology, function, and biomedical applications of exosomes

open access: yesScience, 2020
Clinical uses of cellular communication Exosomes are a type of extracellular vesicle that contain constituents (protein, DNA, and RNA) of the cells that secrete them.
R. Kalluri, Valerie S. LeBleu
semanticscholar   +1 more source

Structure Elucidation and Biochemical Characterization of Environmentally Relevant Novel Extradiol Dioxygenases Discovered by a Functional Metagenomics Approach

open access: yesmSystems, 2019
The release of synthetic chemical pollutants in the environment is posing serious health risks. Enzymes, including oxygenases, play a crucial role in xenobiotic degradation. In the present study, we employed a functional metagenomics approach to overcome
Chandni Sidhu   +3 more
doaj   +3 more sources

NK cell-based cancer immunotherapy: from basic biology to clinical development

open access: yesJournal of Hematology & Oncology, 2021
Natural killer (NK) cell is a specialized immune effector cell type that plays a critical role in immune activation against abnormal cells. Different from events required for T cell activation, NK cell activation is governed by the interaction of NK ...
Sizhe Liu   +5 more
semanticscholar   +1 more source

Overview of the biology of type I interferons [PDF]

open access: yesArthritis Research & Therapy, 2010
Type I interferons are pleiotropic cytokines with antiviral, antitumor and immunoregulatory functions. An aspect of their complex biology is the paradox that, depending on context, type I interferons can be anti-inflammatory and tissue protective or can be proinflammatory and promote autoimmunity.
Lionel B. Ivashkiv   +2 more
openaire   +2 more sources

Nutritional systems biology of type 2 diabetes [PDF]

open access: yesGenes & Nutrition, 2015
Type 2 diabetes (T2D) has become an increasingly challenging health burden due to its high morbidity, mortality, and heightened prevalence worldwide. Although dietary and nutritional imbalances have long been recognized as key risk factors for T2D, the underlying mechanisms remain unclear. The advent of nutritional systems biology, a field that aims to
Zhao, Yuqi   +2 more
openaire   +4 more sources

The cell repair research for Parkinson’s disease: A systematic review

open access: yesJournal of Neurorestoratology, 2020
Background and Objective:Parkinson’s disease (PD) is a common neurodegenerative disease. Previous studies have demonstrated the effect of cell-based therapies, but their clinical efficacy and safety have not been evaluated.
Chao Chen   +7 more
doaj   +1 more source

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