Results 11 to 20 of about 16,281,457 (341)

Structure Elucidation and Biochemical Characterization of Environmentally Relevant Novel Extradiol Dioxygenases Discovered by a Functional Metagenomics Approach

open access: yesmSystems, 2019
The release of synthetic chemical pollutants in the environment is posing serious health risks. Enzymes, including oxygenases, play a crucial role in xenobiotic degradation. In the present study, we employed a functional metagenomics approach to overcome
Chandni Sidhu   +3 more
doaj   +3 more sources

Sex differences in neutrophil biology modulate response to type I interferons and immunometabolism

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Despite clear differences in female and male immunity that may contribute to variations in response to infections and predisposition to cancer and autoimmunity, the exact mechanisms that drive this stark contrast remain insufficiently ...
Sarthak Gupta   +24 more
semanticscholar   +1 more source

Bone Turnover Markers: Basic Biology to Clinical Applications

open access: yesEndocrine reviews, 2022
Bone turnover markers (BTMs) are used widely, in both research and clinical practice. In the last 20 years, much experience has been gained in measurement and interpretation of these markers, which include commonly used bone formation markers (bone ...
M. Schini   +4 more
semanticscholar   +1 more source

Where Do You Get Your Protein? Or: Biochemical Realization [PDF]

open access: yes, 2020
Biochemical kinds such as proteins pose interesting problems for philosophers of science, as they can be studied from the points of view of both biology and chemistry.
Tahko, Tuomas E.
core   +3 more sources

Clinical Biology of the Pituitary Adenoma

open access: yesEndocrine reviews, 2022
All endocrine glands are susceptible to neoplastic growth, yet the health consequences of these neoplasms differ between endocrine tissues. Pituitary neoplasms are highly prevalent and overwhelmingly benign, exhibiting a spectrum of diverse behaviors and
S. Melmed   +12 more
semanticscholar   +1 more source

NK cell-based cancer immunotherapy: from basic biology to clinical development

open access: yesJournal of Hematology & Oncology, 2021
Natural killer (NK) cell is a specialized immune effector cell type that plays a critical role in immune activation against abnormal cells. Different from events required for T cell activation, NK cell activation is governed by the interaction of NK ...
Sizhe Liu   +5 more
semanticscholar   +1 more source

The cell repair research for Parkinson’s disease: A systematic review

open access: yesJournal of Neurorestoratology, 2020
Background and Objective:Parkinson’s disease (PD) is a common neurodegenerative disease. Previous studies have demonstrated the effect of cell-based therapies, but their clinical efficacy and safety have not been evaluated.
Chao Chen   +7 more
doaj   +1 more source

IMPACT OF SOIL TYPE, BIOLOGY AND TEMPERATURE ON THE SURVIVAL OF NON-TOXIGENIC ESCHERICHIA COLI O157

open access: yesBiology and Environment: Proceedings of the Royal Irish Academy, 2013
:The occurrence of microbial enteropathogens in the environment can represent a serious risk to human health. The fate of enteropathogens introduced into the soil environment is dependent on a wide range of complex interacting environmental factors ...
E. Moynihan   +4 more
semanticscholar   +1 more source

Use of Stem Cell Extracellular Vesicles as a “Holistic” Approach to CNS Repair

open access: yesFrontiers in Cell and Developmental Biology, 2020
Neurodegeneration is a hallmark of many diseases and disorders of the central nervous system (CNS). High levels of neuroinflammation are often associated with irreparable damage to CNS cells due to the dysregulation of signaling cascades that are unable ...
Heather Branscome   +8 more
doaj   +1 more source

Beta cell and immune cell interactions in autoimmune type 1 diabetes: How they meet and talk to each other

open access: yesMolecular Metabolism, 2022
Background: The highly complex pathogenesis of Type 1 Diabetes is driven by several immune cell types with both effector and regulatory characteristics, which ultimately ends in the destruction of the insulin-producing beta cells.
Martin G. Scherm   +5 more
doaj   +1 more source

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