Results 231 to 240 of about 15,925,070 (360)

AI-based identification of therapeutic agents targeting GPCRs: introducing ligand type classifiers and systems biology

open access: diamond, 2023
Jonas Goßen   +6 more
openalex   +2 more sources

Aberrant expression of nuclear prothymosin α contributes to epithelial‐mesenchymal transition in lung cancer

open access: yesMolecular Oncology, EarlyView.
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen   +12 more
wiley   +1 more source

Novel insights into post-myocardial infarction cardiac remodeling through algorithmic detection of cell-type composition shifts. [PDF]

open access: yesPLoS Genet
Gural B   +13 more
europepmc   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Editorial Overview: “Islet Biology in Type 2 Diabetes”

open access: yesJournal of Molecular Biology, 2020
Gaisano, Herbert Y.   +2 more
openaire   +4 more sources

Correction: Engineering of a chitin deacetylase to generate tailor-made chitosan polymers. [PDF]

open access: yesPLoS Biol
Bonin M   +6 more
europepmc   +1 more source

Telomere biology and metabolic disorders: the role of insulin resistance and type 2 diabetes

open access: hybrid, 2020
Е. N. Dudinskaya   +4 more
openalex   +2 more sources

Lipid droplets and liver disease: from basic biology to clinical implications

open access: yesNature Reviews Gastroenterology &Hepatology, 2017
N. Gluchowski   +3 more
semanticscholar   +1 more source

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