A SELECTIVE HYDROLYSIS OF DIFFERENT TYPES OF SPHINGOPHOSPHOLIPIDS BY PHOSPHOLIPASE C
A study on the specificity of phospholipase C activity(EC 3.1.4.3)revealed that more than 90% of sphingophospholipids constituting normal fatty acid as the amide linkage e.g. sphingomyelin, ceramide 2-aminoethylphoshonate(CAEP), ceramide phosphorylethanolamine (CPEA) and ceramide N-methyl 2-aminoethylphosphonate(CMAEP), could be hydrolyzed for 20h ...
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Decidualization is the process by which human endometrial stromal cells undergo morphological and functional changes to prepare the uterus for embryo implantation and support pregnancy. Our study identifies the phosphatidic acid‐Src‐FAK‐RhoA/ROCK signaling pathway as a critical regulator of the cytoskeletal alterations required for this transformation.
Hyeon‐Jeong Jun+5 more
wiley +1 more source
Search for and functional annotation of multi-domain PLA2 family proteins in flatworms.
Bocharnikova ME+2 more
europepmc +1 more source
High expression of PLA2G2A in fibroblasts plays a crucial role in the early progression of carotid atherosclerosis. [PDF]
Wang X+10 more
europepmc +1 more source
Lateral mobility of the phospholipase C-activating vasopressin V1-type receptor in A7r5 smooth muscle cells: a comparison with the adenylate cyclase-coupled V2-receptor. [PDF]
David A. Jans+2 more
openalex +1 more source
A novel acetyl xylan esterase was discovered from Aspergillus oryzae. The deacetylase activity toward wheat arabinoxylan increased synergistically with xylanase addition. The crystal structure exhibited hybrid features between two α/β‐hydrolase families, highlighting its structural uniqueness.
Chihaya Yamada+4 more
wiley +1 more source
Molecular Evolution and Adaptation Strategies in Marine Ciliates: An Inspiration for Cold-Adapted Enzyme Engineering and Drug Binding Analysis. [PDF]
Pucciarelli S+4 more
europepmc +1 more source
RNAseq and differential expression analysis identified 15 salivary gland genes encoding secreted proteins with putative anti‐bacterial, anti‐fungal, cytolytic, digestive and immunosuppressive function. The three most highly transcribed genes were selected to study their functional importance by reverse genetics, using a non‐invasive approach of dsRNA ...
Andrea Becchimanzi+9 more
wiley +1 more source
Contribution of individual phospholipase A<sub>2</sub> enzymes to the cleavage of oxidized phospholipids in human blood plasma. [PDF]
Jokesch P+4 more
europepmc +1 more source