Results 91 to 100 of about 476,925 (305)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Expression of the mouse α1(II) collagen gene is not restricted to cartilage during development [PDF]

open access: yes, 1991
The mouse alpha 1(II) collagen gene has been isolated and a 5' portion of the gene which has low homology to other collagen genes was used to study the pattern of expression during mouse embryogenesis. In situ hybridization studies show that in the mouse,
Au, PKC, Cheah, KSE, Lau, ET, Tam, PPL
core  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Region specific microstructural complexity of the ovine meniscus root provides an organizational basis for injury susceptibility

open access: yesScientific Reports
Comprehensive information on the meniscus root microstructure is essential to exactly understand its physiological role and susceptibility to injury. We selected the ovine medial meniscus anterior root (MAR) as model to elucidate the intricate spatial ...
Marta Carretero-Hernández   +4 more
doaj   +1 more source

Salinomycin causes dedifferentiation via the extracellular signal-regulated kinase (ERK) pathway in rabbit articular chondrocytes

open access: yesJournal of Pharmacological Sciences, 2015
Salinomycin (SAL), a monocarboxylic polyether antibiotic isolated from Streptomyces albus, modulates various cellular responses, including proliferation, apoptosis, and inflammation.
Seon-Mi Yu, Song-Ja Kim
doaj   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

open access: yesArthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos   +2 more
wiley   +1 more source

Prostaglandin E2 role in inhibition of joint cartilage collagen destruction in patients with osteoarthritis

open access: yesНаучно-практическая ревматология, 2009
Prostaglandin E2 role in inhibition of articular cartilage collagen degradation in patients with osteoarthritis. Objective. To assess prostaglandin E2 (PGE2) role in inhibition of type II collagen digestion in explants of articular cartilage of pts with ...
E V Chetina, D DiBattista, A R Pool
doaj   +1 more source

Influence of alginate on type II collagen fibrillogenesis

open access: yesJournal of Materials Science: Materials in Medicine, 2005
Collagen II is the majority of extracellular matrix components in articular cartilage, which with the major functions of preventing expansion of the tissue and distributing the load of body weight. To obtain man-made ECM, the reconstitution of collagen could be conducted in the presence of negatively charged polysaccharide, such as alginate.
Shyh Ming, Kuo   +4 more
openaire   +2 more sources

Synthesis of a Novel Thermoresponsive S53P4 Bioactive Glass Extract–Poloxamer 407 Injectable Hydrogels: Assessment of Biocompatibility and Antimicrobial Properties

open access: yesAdvanced Engineering Materials, EarlyView.
This study investigates innovative thermoreversible hydrogels derived from S53P4 bioactive glass extracts to aid in the healing of infected diabetic foot wounds. These injectable gels, which gel at body temperature, release beneficial ions and remain stable over time.
Marian G. Vargas Guerrero   +9 more
wiley   +1 more source

Muscle fibre typing, collagen composition analysis of breast and thigh meats in two breeds of chicken of different growth performance [PDF]

open access: yes, 2010
The present study was done to evaluate the type of muscle fibre composition in thigh and breast muscle of Red Jungle fowl and Ross. It was also to evaluate the collagen composition in thigh and breast muscle of Red Jungle fowl and Ross.
Abu Bakar @ Zakaria, Md Zuki   +1 more
core  

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