Results 141 to 150 of about 286,259 (301)
Advanced Healthcare Materials, EarlyView.A long‐lived, five‐cell‐type human neurovascular (PENTA) model recreates vascular disorganization and incomplete repair after traumatic brain injury (TBI). By integrating endothelial, glial, neuronal, and immune components within a 3D scaffold, the platform enables time‐resolved analysis of neurovascular remodeling and provides a human‐relevant system ...
Daniel S. Hinrichsen +6 more
wiley +1 more source
The biology of the ovine functional spinal unit: facet cartilage and intervertebral disc [PDF]
, 2013 Back pain will affect up to 84 % of people at some point in their lives. It is a major public health problem in Western society leading to disability and economic loss through work absence, physician visits and hospitalisation.
Gough, Caroline Shanni
core
Effects of mechanical vibrations on chondrocytes in monolayer culture for regenerative cartilage
Mechanical Engineering JournalCartilage regenerative medicine requires time and effort to regenerate thick hyaline cartilage. In this study, we investigated the effects of mechanical vibrations on chondrocyte proliferation and cartilage matrix production to simplify the regenerative ...
Yura WATANABE, Toshihiko SHIRAISHI
doaj +1 more source
Design and Synthesis of Peptide‐Polyester Conjugates for Cell‐Mediated Scaffold Degradation
Advanced Healthcare Materials, EarlyView.This work describes polycaprolactone (PCL)‐based biomaterials engineered to degrade in response to cell‐secreted proteases. A fast‐degrading peptide (Fast) sequence is integrated into a PCL conjugate backbone to produce a biomaterial that is selectively degraded by multiple cell types compared to its scrambled control (ScrFast).
Korina Vida G. Sinad +7 more
wiley +1 more source
Electrospinning of collagen type II: A feasibility study
, 2003 Collagen is the natural scaffolding found in all tissues and has been explored extensively for use as a tissue engineering scaffold with limited success.
Wnek, Gary E. +4 more
core +1 more source
Abstract Undenatured type II collagen (UC-II) represents a unique category of joint health intervention, mechanistically distinct from hydrolyzed collagen or amino acid supplementation. By retaining its native triple-helical epitopes, UC-II engages the mechanism of oral tolerance, wherein antigens presented through gut-associated lymphoid tissue ...
openaire +1 more source
Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy
Advanced Healthcare Materials, EarlyView.Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima +15 more
wiley +1 more source
This study presents new injectable hydrogels based on hyaluronic acid and collagen type II that mimic the polysaccharide-protein structure of natural cartilage. After collagen isolation from chicken sternal cartilage, tyramine-grafted hyaluronic acid and
Gantenbein, Benjamin +3 more
core +1 more source
Advanced Healthcare Materials, EarlyView.Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez +6 more
wiley +1 more source
Expression of collagen type�I and type�II in consecutive stages of human osteoarthritis
, 2004 In normal hyaline cartilage the predominant collagen type is collagen type II along with its associated collagens, for example, types IX and XI, produced by normal chondrocytes.
Maelicke, C. +7 more
core +1 more source