Results 1 to 10 of about 276,775 (214)

Higher Prevalence of PldA, a Pseudomonas aeruginosa Trans-Kingdom H2-Type VI Secretion System Effector, in Clinical Isolates Responsible for Acute Infections and in Multidrug Resistant Strains

Frontiers in Microbiology, 2018
Pseudomonas aeruginosa can manipulate eukaryotic host cells using secreted effectors delivered by the type III or the type VI Secretion Systems (T3SS and T6SS). The T3SS allows the injection of bacterial effectors (Exo toxins) into eukaryotic cell.
Thibaud Boulant, Yves-Marie Boudehen, Alain Filloux, Patrick Plesiat, Thierry Naas, Thierry Naas, Thierry Naas, Laurent Dortet, Laurent Dortet, Laurent Dortet, Laurent Dortet   +10 more
doaj   +1 more source

Animal Models of Type III Secretion System-Mediated Pathogenesis

Pathogens, 2019
The type III secretion system (T3SS) is a conserved virulence factor used by many Gram-negative pathogenic bacteria and has become an important target for anti-virulence drugs.
Julia A. Hotinger, Aaron E. May
doaj   +1 more source

Migration of Type III Secretion System Transcriptional Regulators Links Gene Expression to Secretion

mBio, 2018
Many plant-pathogenic bacteria of considerable economic importance rely on type III secretion systems (T3SSs) of the Hrc-Hrp 1 family to subvert their plant hosts.
Spyridoula N. Charova, Anastasia D. Gazi, Efstratios Mylonas, Charalambos Pozidis, Blanca Sabarit, Dimitrios Anagnostou, Konstantina Psatha, Michalis Aivaliotis, Carmen R. Beuzon, Nickolas J. Panopoulos, Michael Kokkinidis   +10 more
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Characterization of Pseudomonas alliivorans strains isolated from Georgia, USA: insights into genomic diversity and pathogenicity in onions

Applied and Environmental Microbiology
Pseudomonas alliivorans is an important emerging pathogen affecting numerous crops. The species is closely related to Pseudomonas viridiflava, with which P. alliivorans strains were often misidentified in the past.
Mei Zhao, Michelle Pena Maclellan, Anuj Lamichhane, Sujan Paudel, Ron Gitaitis, Brian Kvitko, Bhabesh Dutta   +6 more
doaj   +1 more source

Comparative genomics of Xanthomonas fragariae and Xanthomonas arboricola pv. fragariae reveals intra- and interspecies variations

Phytopathology Research, 2020
The quarantine bacterium Xanthomonas fragariae causes angular leaf spots on strawberry. Its population structure was recently found to be divided into four (sub)groups resulting from two distinct main groups. Xanthomonas arboricola pv.
Michael Gétaz, Jochen Blom, Theo H. M. Smits, Joël F. Pothier   +3 more
doaj   +1 more source

An optimized growth medium for increased recombinant protein secretion titer via the type III secretion system

Microbial Cell Factories, 2021
Background Protein secretion in bacteria is an attractive strategy for heterologous protein production because it retains the high titers and tractability of bacterial hosts while simplifying downstream processing.
Lisa Ann Burdette, Han Teng Wong, Danielle Tullman-Ercek   +2 more
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Antibodies Inhibiting the Type III Secretion System of Gram-Negative Pathogenic Bacteria

Antibodies, 2020
Pathogenic bacteria are a global health threat, with over 2 million infections caused by Gram-negative bacteria every year in the United States. This problem is exacerbated by the increase in resistance to common antibiotics that are routinely used to ...
Julia A. Hotinger, Aaron E. May
doaj   +1 more source

T3DB: an integrated database for bacterial type III secretion system

BMC Bioinformatics, 2012
Background Type III Secretion System (T3SS), which plays important roles in pathogenesis or symbiosis, is widely expressed in a variety of gram negative bacteria. However, lack of unique nomenclature for T3SS genes has hindered T3SS related research.
Wang Yejun, Huang He, Sun Ming’an, Zhang Qing, Guo Dianjing   +4 more
doaj   +1 more source

Exoenzyme Y Contributes to End-Organ Dysfunction Caused by Pseudomonas aeruginosa Pneumonia in Critically Ill Patients: An Exploratory Study

Toxins, 2020
Pseudomonas aeruginosa is an opportunistic pathogen that causes pneumonia in immunocompromised and intensive care unit (ICU) patients. During host infection, P. aeruginosa upregulates the type III secretion system (T3SS), which is used to intoxicate host
Brant M. Wagener, Naseem Anjum, Sarah C. Christiaans, Morgan E. Banks, Jordan C. Parker, Adam T. Threet, Rashidra R. Walker, Kayla D. Isbell, Stephen A. Moser, Troy Stevens, Mikhail F. Alexeyev, Jonathon P. Audia, Wito Richter, Kierra S. Hardy, Lina Abou Saleh, Charity Morgan, Jean-François Pittet   +16 more
doaj   +1 more source

The Type III Secretion System-Related CPn0809 from Chlamydia pneumoniae. [PDF]

PLoS ONE, 2016
Chlamydia pneumoniae is an intracellular Gram-negative bacterium that possesses a type III secretion system (T3SS), which enables the pathogen to deliver, in a single step, effector proteins for modulation of host-cell functions into the human host cell ...
Astrid C Engel, Frauke Herbst, Anne Kerres, Jan N Galle, Johannes H Hegemann   +4 more
doaj   +1 more source