Characterisation of the effects of salicylidene acylhydrazide compounds on type three secretion in Escherichia coli O157:H7 [PDF]
Recent work has highlighted a number of compounds that target bacterial virulence by affecting gene regulation. In this work, we show that small-molecule inhibitors affect the expression of the type III secretion system (T3SS) of <i>Escherichia ...
Layton, Abigail +23 more
core +1 more source
Type VI secretion system : secretion by a contractile nanomachine [PDF]
The type VI secretion systems (T6SS) are present in about a quarter of all Gram-negative bacteria. Several key components of T6SS are evolutionarily related to components of contractile nanomachines such as phages and R-type pyocins. The T6SS assembly is
Basler, Marek, Basler M
core +1 more source
Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains [PDF]
The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium.
Chalmers, James +16 more
core +1 more source
CagI is an essential component of the Helicobacter pylori Cag type IV secretion system and forms a complex with CagL. [PDF]
Helicobacter pylori, the causative agent of type B gastritis, peptic ulcers, gastric adenocarcinoma and MALT lymphoma, uses the Cag type IV secretion system to induce a strong proinflammatory response in the gastric mucosa and to inject its effector ...
Haas, Rainer +17 more
core +2 more sources
Harpin of Pseudomonas syringae pv. phaseolicola Harbors a Protein Binding Site
Harpin HrpZ of plant-pathogenic bacterium Pseudomonas syringae elicits a hypersensitive response (HR) in some nonhost plants, but its function in the pathogenesis process is still obscure.
Chun-Mei Li +5 more
doaj +1 more source
Effective identification of bacterial type III secretion signals using joint element features. [PDF]
Type III secretion system (T3SS) plays important roles in bacteria and host cell interactions by specifically translocating type III effectors into the cytoplasm of the host cells.
Yejun Wang +4 more
doaj +1 more source
Nitric Oxide Regulates the Ralstonia solanacearum Type III Secretion System
Ralstonia solancearum causes bacterial wilt disease on diverse plant hosts. R. solanacearum cells enter a host from soil or infested water through the roots, then multiply and spread in the water-transporting xylem vessels.
Connor G. Hendrich +3 more
doaj +1 more source
Characterization of the SPI-1 and Rsp type three secretion systems in Pseudomonas fluorescens F113 [PDF]
Pseudomonas fluorescens F113 is a plant growthpromoting rhizobacterium (PGPR) isolated from the sugar beet rhizosphere. The recent annotation of the F113 genome sequence has revealed that this strain encodes a wide array of secretion systems, including ...
Matthieu Barret +12 more
core +1 more source
A Phosphorylation Switch on Lon Protease Regulates Bacterial Type III Secretion System in Host
Most pathogenic bacteria deliver virulence factors into host cytosol through type III secretion systems (T3SS) to perturb host immune responses. The expression of T3SS is often repressed in rich medium but is specifically induced in the host environment.
Xiaofeng Zhou +6 more
doaj +1 more source
Diversity of virulence phenotypes among type III secretion negative Pseudomonas aeruginosa clinical isolates. [PDF]
Pseudomonas aeruginosa is a frequent cause of acute infections. The primary virulence factor that has been linked to clinical disease is the type III secretion system, a molecular syringe that delivers effector proteins directly into host cells.
Jonida Toska +6 more
doaj +1 more source

