Results 51 to 60 of about 26,046,637 (294)

Diversity of virulence phenotypes among type III secretion negative Pseudomonas aeruginosa clinical isolates. [PDF]

PLoS ONE, 2014
Pseudomonas aeruginosa is a frequent cause of acute infections. The primary virulence factor that has been linked to clinical disease is the type III secretion system, a molecular syringe that delivers effector proteins directly into host cells.
Jonida Toska, Yan Sun, Dalina Alvarez Carbonell, Altreisha N-S Foster, Michael R Jacobs, Eric Pearlman, Arne Rietsch   +6 more
doaj   +1 more source

Heterogeneity in ess transcriptional organization and variable contribution of the Ess/Type VII protein secretion system to virulence across closely related Staphylocccus aureus strains [PDF]

, 2014
The Type VII protein secretion system, found in Gram-positive bacteria, secretes small proteins, containing a conserved W-x-G amino acid sequence motif, to the growth medium.
Chalmers, James, Jäger, Franziska, van der Kooi - Pol, Magda, Cargill, James S, Cao, Zhen Ping, van der Kooi-Pol, Magdalena M., Hunter, William N., Palmer, Tracy, Ryan, Robert P., Kneuper, Holger, Twomey, Kate B., Ryan, Robert P, Zoltner, Martin, Twomey, Kate B, Cargill, James S., van Dijl, Jan Maarten, Hunter, William N   +16 more
core   +2 more sources

Type III Secretion: More Systems Than You Think

Physiology, 2005
The type III secretion (T3S) pathway allows bacteria to inject effector proteins into the cytosol of target animal or plant cells. T3S systems evolved into seven families that were distributed among Gram-negative bacteria by horizontal gene transfer. There are probably a few hundred effectors interfering with control and signaling in eukaryotic cells ...
Troisfontaines, P., Cornelis, G. R.
openaire   +5 more sources

Atomic model of the type III secretion system needle [PDF]

Nature, 2012
Pathogenic bacteria using a type III secretion system (T3SS) to manipulate host cells cause many different infections including Shigella dysentery, typhoid fever, enterohaemorrhagic colitis and bubonic plague. An essential part of the T3SS is a hollow needle-like protein filament through which effector proteins are injected into eukaryotic host cells ...
Loquet, Antoine, Sgourakis, Nikolaos, Gupta, Rashmi, Giller, Karin, Riedel, Dietmar, Goosmann, Christian, Griesinger, Christian, Kolbe, Michael, Baker, David, Becker, Stefan, Lange, Adam   +10 more
openaire   +7 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Assembly and arrangement of the type three secretion system of "yersinia enterocolitica" [PDF]

, 2014
The type three secretion system (T3SS) is a bacterial weapon found in many Gram-negative bacteria. It consists out of a needle like structure called injectisome, which enables bacteria to inject effector proteins into eukaryotic cells. The injectisome is
Amstutz, Marlise
core   +1 more source

Cellular subversion: towards a complete repertoire of type-III secretion system effectors in enterohaemorrhagic Escherichia coli O157:H7 [PDF]

, 2010
Enterohaemorrhagic Escherichia coli (EHEC) O157:H7 is a formidable pathogen that uses a type-III secretion system to inject bacterial ‘effector’ proteins directly into host cells. Most effectors that are encoded within the locus of enterocyte effacement (
Matthews, Sophie Anne
core   +7 more sources

Exploiting the bacterial type III secretion system of

Current Research in Biotechnology
The Gram-negative bacterium Pseudomonas aeruginosa encodes a Type III Secretion System (T3SS), a molecular syringe that injects bacterially-synthesized effector proteins directly into a target mammalian host cell. While classically studied in the context
Amanda N. Tuckey, Jennifer Clark, Rasha Q. Al-Rahahleh, Aisha H. Siddiqui, Steven A. DeFreitas, Wynand P. Roos, Mike T. Lin, Jonathon P. Audia, Robert W. Sobol   +8 more
doaj   +1 more source

A Phosphorylation Switch on Lon Protease Regulates Bacterial Type III Secretion System in Host

mBio, 2018
Most pathogenic bacteria deliver virulence factors into host cytosol through type III secretion systems (T3SS) to perturb host immune responses. The expression of T3SS is often repressed in rich medium but is specifically induced in the host environment.
Xiaofeng Zhou, Doron Teper, Maxuel O. Andrade, Tong Zhang, Sixue Chen, Wen-Yuan Song, Nian Wang   +6 more
doaj   +1 more source

Role of the Type VI Secretion System in the Pathogenicity of Pseudomonas syringae pv. actinidiae, the Causative Agent of Kiwifruit Bacterial Canker

Frontiers in Microbiology, 2021
The type VI secretion system (T6SS), a macromolecular machine, plays an important role in the pathogenicity of many Gram-negative bacteria. However, the role of T6SS in the pathogenicity of Pseudomonas syringae pv.
Nana Wang, Nana Wang, Ning Han, Ning Han, Runze Tian, Runze Tian, Jiliang Chen, Jiliang Chen, Xiaoning Gao, Zhiran Wu, Zhiran Wu, Yuqi Liu, Yuqi Liu, Lili Huang, Lili Huang   +14 more
doaj   +1 more source