Results 161 to 170 of about 27,335,054 (258)

Functional consequences of site-directed mutagenesis in the C-terminus of YopN, a Yersinia pseudotuberculosis regulator of Yop secretion

Pathogenic Yersinia spp. utilizes the Ysc-Yop type III secretion system to targetYop effector proteins into the cytosol of host immune cells. Internalizedeffectors alter specific signaling pathways to neutralize immune cell-dependentphagocytosis, killing
Amer, Ayad,, Forsberg, Åke,, Gurung, Jyoti,, Costa, Tiago,, Avican, Ummehan,, Francis, Matthew,   +5 more
core  

Spatially Controlled Embedded Bioprinting of Prevascularized Spheroids‐Containing Biopatch Enables Functional Skin Regeneration

Advanced Healthcare Materials, EarlyView.
A spatially controlled embedded bioprinting strategy enables precise engineering of prevascularized multicellular spheroids within skin‐derived dECM bioinks. Optimized spheroid size, composition, and spacing promote vascular maturation, paracrine signaling, and tissue integration, resulting in enhanced angiogenesis, blood perfusion, and functional skin
Minjun Ahn, Gyu Tae Park, Dongjun Lee, Sik Yoon, Sae‐Ock Oh, Jae Ho Kim, Byoung Soo Kim   +6 more
wiley   +1 more source

TsrA modulates type III secretion system 2 expression as a co-regulator of H-NS in <i>Vibrio parahaemolyticus</i>. [PDF]

J Bacteriol
Sutanto TPW, Pratama A, Ishii E, Iida T, Matsuda S.   +4 more
europepmc   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source

Houttuynia cordata extract protects against Salmonella infection by targeting type III secretion system 1. [PDF]

Poult Sci
Wang T, Cai S, Zhang J, Wang J, Deng X, Ma K, Liu H, Qiu J.   +7 more
europepmc   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

GDNF‐Enriched Small Extracellular Vesicle‐Loaded ROS‐Scavenging Hydrogel Promotes Neural Regeneration After Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
A glial cell line‐derived neurotrophic factor (GDNF)‐enriched small extracellular vesicle‐loaded reactive oxygen species (ROS)‐scavenging hydrogel integrates sustained neurotrophic delivery with local modulation of oxidative and inflammatory stress after spinal cord injury. The composite hydrogel improves local vesicle retention, protects neural tissue,
Xingyu Zhu, Zhong Liu, Kewei Li, Yuhong Fan, Kangjia Yang, Xiaopeng Sun, Hang Shi, Lixuan Sun, Yang Lou, Min Wang, Peipei Wu, Hui Qian, Qiang Fu, Hua Ding   +13 more
wiley   +1 more source

Correction: ExoS effector in Pseudomonas aeruginosa Hyperactive Type III secretion system mutant promotes enhanced Plasma Membrane Rupture in Neutrophils. [PDF]

PLoS Pathog
Reuven AD, Katzenell S, Mwaura BW, Bliska JB.   +3 more
europepmc   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

Gut microbiome-derived indoles differentially suppress type III secretion system-associated virulence in <i>Escherichia coli</i> and <i>Salmonella enterica</i>. [PDF]

Front Microbiol
Shvarthburg M, Taussig D, Even-Tov N, Wine Y, Sal-Man N.   +4 more
europepmc   +1 more source