Self‐Sealing Microneedles Improve Precision and Reduce Reflux in Subretinal Cell Transplantation
Ultrafine 49G microneedles enable subretinal delivery of induced pluripotent stem cell‐derived retinal pigment epithelial cells through a 50 µm outer diameter tip. Compared with conventional 38G microcannulas, these microneedles reduce cell suspension reflux in a rabbit model, highlighting the potential of microinvasive delivery instruments to improve ...
Jared Ching +9 more
wiley +1 more source
Neutralizing human monoclonal antibodies that target the PcrV component of the type III secretion system of <i>Pseudomonas aeruginosa</i> act through distinct mechanisms. [PDF]
Desveaux JM +13 more
europepmc +1 more source
Information Transmission Strategies for Self‐Organized Robotic Aggregation
In this review, we discuss how information transmission influences the neighbor‐based self‐organized aggregation of swarm robots. We focus specifically on local interactions regarding information transfer and categorize previous studies based on the functions of the information exchanged.
Shu Leng +5 more
wiley +1 more source
Shigella type-III secretion system effectors counteract the induction of host inflammation and cell death. [PDF]
Ashida H +5 more
europepmc +1 more source
Cell‐Based Biohybrid Micro/Nanorobots for Biotherapy
This review systematically evaluates cell‐based biohybrid micro/nanorobots (CB‐BMRs), highlighting their cell selection criteria, fabrication strategies, and diverse actuation modes. Furthermore, it surveys the promising therapeutic applications of CB‐BMRs in targeted cancer, thrombosis, and inflammation treatments, while comprehensively discussing ...
Lin Wang +11 more
wiley +1 more source
Magnetically Actuated Microrobot for Drug Delivery: Current Progress and Challenges
Magnetically actuated microrobots are reshaping targeted drug delivery through wireless propulsion, programmable materials, and localized therapeutic release. This review examines how fabrication, body material selection, structural architecture, loading mechanisms, and imaging‐guided control converge to enable microrobotic therapies while identifying ...
Yang Yang, David J. Cappelleri
wiley +1 more source
The Type III Secretion System plasmid pPHDPT3 of Photobacterium damselae subsp. piscicida is stable in Australian isolates due to conserved non-repetitive genomic architecture. [PDF]
Rudenko O, Baseggio L, Barnes AC.
europepmc +1 more source
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
The Catabolite Repression Control Protein Crc Regulates the Type III Secretion System Through the Adenylate Cyclase CyaB in <i>Pseudomonas aeruginosa</i>. [PDF]
Yin L +7 more
europepmc +1 more source

