Results 31 to 40 of about 276,775 (214)

Effective identification of bacterial type III secretion signals using joint element features. [PDF]

PLoS ONE, 2013
Type III secretion system (T3SS) plays important roles in bacteria and host cell interactions by specifically translocating type III effectors into the cytoplasm of the host cells.
Yejun Wang, Ming'an Sun, Hongxia Bao, Qing Zhang, Dianjing Guo   +4 more
doaj   +1 more source

Harpin of Pseudomonas syringae pv. phaseolicola Harbors a Protein Binding Site

Molecular Plant-Microbe Interactions, 2005
Harpin HrpZ of plant-pathogenic bacterium Pseudomonas syringae elicits a hypersensitive response (HR) in some nonhost plants, but its function in the pathogenesis process is still obscure.
Chun-Mei Li, Minna Haapalainen, Justin Lee, Thorsten Nürnberger, Martin Romantschuk, Suvi Taira   +5 more
doaj   +1 more source

Diversity of virulence phenotypes among type III secretion negative Pseudomonas aeruginosa clinical isolates. [PDF]

PLoS ONE, 2014
Pseudomonas aeruginosa is a frequent cause of acute infections. The primary virulence factor that has been linked to clinical disease is the type III secretion system, a molecular syringe that delivers effector proteins directly into host cells.
Jonida Toska, Yan Sun, Dalina Alvarez Carbonell, Altreisha N-S Foster, Michael R Jacobs, Eric Pearlman, Arne Rietsch   +6 more
doaj   +1 more source

Role of the Type VI Secretion System in the Pathogenicity of Pseudomonas syringae pv. actinidiae, the Causative Agent of Kiwifruit Bacterial Canker

Frontiers in Microbiology, 2021
The type VI secretion system (T6SS), a macromolecular machine, plays an important role in the pathogenicity of many Gram-negative bacteria. However, the role of T6SS in the pathogenicity of Pseudomonas syringae pv.
Nana Wang, Nana Wang, Ning Han, Ning Han, Runze Tian, Runze Tian, Jiliang Chen, Jiliang Chen, Xiaoning Gao, Zhiran Wu, Zhiran Wu, Yuqi Liu, Yuqi Liu, Lili Huang, Lili Huang   +14 more
doaj   +1 more source

A Phosphorylation Switch on Lon Protease Regulates Bacterial Type III Secretion System in Host

mBio, 2018
Most pathogenic bacteria deliver virulence factors into host cytosol through type III secretion systems (T3SS) to perturb host immune responses. The expression of T3SS is often repressed in rich medium but is specifically induced in the host environment.
Xiaofeng Zhou, Doron Teper, Maxuel O. Andrade, Tong Zhang, Sixue Chen, Wen-Yuan Song, Nian Wang   +6 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Lactoferrin inhibits E. coli O157:H7 growth and attachment to intestinal epithelial cells

Veterinární Medicína, 2010
Enterohemorrhagic Escherichia coli (EHEC) serotype O157:H7 strains are associated with haemorraghic colitis and haemolytic uremic syndrome (HUS) in humans. Cattle are a reservoir of E. coli O157:H7. We studied the ability of bovine and human lactoferrin,
M. Atef Yekta, F. Verdonck, W. Van Den Broeck, B.M. Goddeeris, E. Cox, D. Vanrompay   +5 more
doaj   +1 more source

Five Plant Natural Products Are Potential Type III Secretion System Inhibitors to Effectively Control Soft-Rot Disease Caused by Dickeya

Frontiers in Microbiology, 2022
Dickeya zeae, a plant soft-rot pathogen, possesses a type III secretion system (T3SS) as one of the major virulence factors, infecting a wide variety of monocotyledonous and dicotyledonous plants and causing serious losses to the production of economic ...
Anqun Hu, Ming Hu, Shanshan Chen, Yang Xue, Xu Tan, Jianuan Zhou   +5 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source