Results 61 to 70 of about 27,042,650 (190)

Enterococcus faecalis Enhances Expression and Activity of the Enterohemorrhagic Escherichia coli Type III Secretion System

mBio, 2019
The gut microbiota can significantly impact invading pathogens and the disease they cause; however, many of the mechanisms that dictate commensal-pathogen interactions remain unclear.
Elizabeth A. Cameron, Vanessa Sperandio, Gary M. Dunny   +2 more
doaj   +1 more source

T3SS chaperone of the CesT family is required for secretion of the anti-sigma factor BtrA in Bordetella pertussis

Emerging Microbes and Infections, 2023
Bordetella pertussis is a Gram-negative, strictly human re-emerging respiratory pathogen and the causative agent of whooping cough. Similar to other Gram-negative pathogens, B.
Jakub Držmíšek, Denisa Petráčková, Ana Dienstbier, Ivana Čurnová, Branislav Večerek   +4 more
doaj   +1 more source

Russian wheat aphid: a model for genomic plasticity and a challenge to breeders

Insect Science, EarlyView.
Invasive foundress finds suitable habitat and reproduces through pathogenesis. Wingless females produce life offspring quickly, which leads to high population densities. High population densities result in competition, which may induce epigenetic changes and wing development for dispersal.
Astrid Jankielsohn, Vicky L. Tolmay, Marlon‐Schylor Luke le Roux, Lintle Mohase, Mpho S. Mafa, Vittorio F. Nicolis, Eduard Venter, Nicolaas Francois Visser Burger, Anna‐Maria Botha   +8 more
wiley   +1 more source

DataSheet1_Identification of Novel Type Three Secretion System (T3SS) Inhibitors by Computational Methods and Anti-Salmonella Evaluations.docx

, 2021
Three type III secretion system (T3SS) inhibitors (compounds 5, 19, and 32) were identified by virtual screening and biological evaluation. These three compounds were evaluated against a panel of Salmonella species strains including S.
Guanghui Zhang (450175), Yonghui Wang (287491), Lei Zhou (19808), Meihui Hou (5697470), Changfa Wang (390394), Zhaodong Kan (11710838), Yunxia Li (670309)   +6 more
core   +1 more source

Structural and biochemical characterization of SrcA, a multi-cargo type III secretion chaperone in Salmonella required for pathogenic association with a host. [PDF]

PLoS Pathogens, 2010
Many Gram-negative bacteria colonize and exploit host niches using a protein apparatus called a type III secretion system (T3SS) that translocates bacterial effector proteins into host cells where their functions are essential for pathogenesis.
Colin A Cooper, Kun Zhang, Sara N Andres, Yuan Fang, Natalia A Kaniuk, Mandy Hannemann, John H Brumell, Leonard J Foster, Murray S Junop, Brian K Coombes   +9 more
doaj   +1 more source

Prediction of type III secretion signals in genomes of gram-negative bacteria [PDF]

, 2009
Background: Pathogenic bacteria infecting both animals as well as plants use various mechanisms to transport virulence factors across their cell membranes and channel these proteins into the infected host cell.
Löwer, Martin, Löwer Martin, Martin Löwer, Schneider, Gisbert (Prof. Dr.), Gisbert Schneider, Schneider Gisbert   +5 more
core   +2 more sources

Harnessing Natural Diversity and Rational Design for Enhanced Plant Immunity

Plant, Cell &Environment, Volume 49, Issue 11, Page 8643-8656, November 2026.
ABSTRACT Plant pathogens cause crop loss. Genetic resistance, through natural genetic diversity or engineered resistance, can be highly effective in protecting plants from infection. Genetic resistance from wild relatives of crops has been successfully introduced into crops to control pathogen infection.
Nathan Diplock, Jennifer D. Lewis
wiley   +1 more source

Edwardsiella tarda-Induced Cytotoxicity Depends on Its Type III Secretion System and Flagellin

, 2014
Many Gram-negative bacteria utilize a type III secretion system (T3SS) to translocate virulence proteins into host cells to cause diseases. In responding to infection, macrophages detect some of the translocated proteins to activate caspase-1-mediated ...
Holden, David W., Nie, Pin, Yu, Xiu-Jun, Lu, Jin-Fang, Rolhion, Nathalie, Zhou, Ying, Xie, Hai-Xia   +6 more
core   +1 more source

On the role of the sorting platform in hierarchical type III secretion regulation in enteropathogenic Escherichia coli

Journal of Bacteriology
The virulence of enteropathogenic Escherichia coli (EPEC) depends on a type III secretion system (T3SS), a membrane-spanning apparatus that injects effector proteins into the cytoplasm of target enterocytes.
Arely Marcos-Vilchis, Norma Espinosa, Adrián F. Alvarez, José L. Puente, J. Eduardo Soto, Bertha González-Pedrajo   +5 more
doaj   +1 more source

Identification of Benzyloxy Carbonimidoyl Dicyanide Derivatives as Novel Type III Secretion System Inhibitors via High-Throughput Screening

Frontiers in Plant Science, 2019
The type III secretion system (T3SS) in many Gram-negative bacterial pathogens is regarded as the most critical virulence determinant and an attractive target for novel anti-virulence drugs.
Yi-Nan Ma, Liang Chen, Liang Chen, Nai-Guo Si, Wen-Jun Jiang, Zhi-Gang Zhou, Jun-Li Liu, Li-Qun Zhang   +7 more
doaj   +1 more source