Results 131 to 140 of about 40,764 (218)

Meningococci drive host membrane tubulation to recruit their signaling receptors

Nature Communications
Once passed into the bloodstream, bacterial pathogens have a limited time to interact with permissive receptors at the surface of host cells. Neisseria meningitidis has developed an extremely effective strategy allowing it to find its receptors in a few ...
Audrey Laurent-Granger, Kévin Sollier, Bruno Saubamea, Virginie Mignon, Nicolas Goudin, Yaëlle Wormser, Morgane Wuckelt, Mahmoud Rifai, Thomas Heng, Lya L’hermitte, Marta Conflitti, Julie Meyer, Hervé Lecuyer, Anne Jamet, Nicolas Borghi, Philippe Girard, Emmanuelle Bille, Grégory Lavieu, Eric Rubinstein, Stefano Marullo, Mathieu Coureuil   +20 more
doaj   +1 more source

Cooperative retraction of bundled type IV pili enables nanonewton force generation.

PLoS Biology, 2008
The causative agent of gonorrhea, Neisseria gonorrhoeae, bears retractable filamentous appendages called type IV pili (Tfp). Tfp are used by many pathogenic and nonpathogenic bacteria to carry out a number of vital functions, including DNA uptake ...
Nicolas Biais, Benoît Ladoux, Dustin Higashi, Magdalene So, Michael Sheetz   +4 more
doaj   +1 more source

A second large plasmid encodes conjugative transfer and antimicrobial resistance in O119:H2 and some typical O111 enteropathogenic \u3ci\u3eEscherichia coli\u3c/i\u3e strains [PDF]

, 2007
A novel and functional conjugative transfer system identified in O119:H2 enteropathogenic Escherichia coli (EPEC) strain MB80 by subtractive hybridization is encoded on a large multidrug resistance plasmid, distinct from the well-described EPEC adherence
Mucci, Tania, Nwaneshiudu, Adaobi I., Okeke, Iruka N., Pickard, Derek J.   +3 more
core   +1 more source

Rapid cytoskeletal response of epithelial cells to force generation by type IV pili.

PLoS ONE, 2011
Many bacterial pathogens interfere with cellular functions including phagocytosis and barrier integrity. The human pathogen Neissieria gonorrhoeae generates grappling hooks for adhesion, spreading, and induction of signal cascades that lead to formation ...
Dirk Opitz, Berenike Maier
doaj   +1 more source

PilY proteins: bimodular drivers of type IV pilus versatility

Trends in Microbiology
Type IV pili (T4P) are dynamic surface fibers that mediate diverse bacterial activities, including adhesion, twitching motility, horizontal gene transfer, biofilm formation, and virulence. The PilY family of T4P-associated proteins are found across a wide range of bacterial species and are critical for key T4P functions. PilY proteins are characterized
Yount, Taylor A., Shukla, Niharika, Chang, Yi-Wei, Geme, Joseph W. St.   +3 more
openaire   +3 more sources

Novel applications of shotgun phage display [PDF]

, 2004
In a shotgun phage display library, theoretically, the entire proteome of a bacterium is represented. Phages displaying specific polypeptides can be isolated by affinity selection, while the corresponding gene remains physically linked to the gene ...
Rosander, Anna
core  

Bacterial Mechanosensing with Type IV Pili [PDF]

Biophysical Journal, 2018
Lorenzo Tala, Xavier Pierrat, Alexandre Persat   +2 more
openaire   +1 more source

Diclofenac sensitizes multi-drug resistant Acinetobacter baumannii to colistin.

PLoS Pathogens
Acinetobacter baumannii causes life-threatening infections that are becoming difficult to treat due to increasing rates of multi-drug resistance (MDR) among clinical isolates.
Fabiana Bisaro, Clay D Jackson-Litteken, Jenna C McGuffey, Anna J Hooppaw, Sophie Bodrog, Leila Jebeli, Manon Janet-Maitre, Juan C Ortiz-Marquez, Tim van Opijnen, Nichollas E Scott, Gisela Di Venanzio, Mario F Feldman   +11 more
doaj   +1 more source

Microbial nanowires: type IV pili or cytochrome filaments? [PDF]

Trends Microbiol, 2023
Wang F, Craig L, Liu X, Rensing C, Egelman EH.   +4 more
europepmc   +1 more source

Pili de type IV [PDF]

médecine/sciences, 2009
openaire   +1 more source