Results 71 to 80 of about 11,396,305 (309)

Compositional synthesis of discrete event systems via synthesis equivalence [PDF]

, 2008
A two-pass algorithm for compositional synthesis of modular supervisors for largescale systems of composed finite-state automata is proposed. The first pass provides an efficient method to determine whether a supervisory control problem has a solution ...
Malik, Robi, Flordal, Hugo
core  

A Review on Kinematically Redundant Parallel Mechanisms With Configurable Platforms

SmartBot
Parallel mechanisms (PMs) are known for their precision, stiffness, and load‐carrying capacity. However, the rigidity of their end‐effectors limits adaptability in tasks involving multi‐point interaction or the manipulation of irregular objects.
Chunxu Tian, Dan Zhang
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Concise Synthesis of Iminocyclitols via Petasis-Type Aminocyclization

, 2016
Concise Synthesis of Iminocyclitols via Petasis-Type ...
Yu Fu (16582), Masakazu Sugiyama (1567081), Chi-Huey Wong (63704), Zhangyong Hong (427808), Lei Liu (5074)   +4 more
core   +1 more source

Transition-Metal-Catalyzed Suzuki-Miyaura-Type Cross-Coupling Reactions of π-Activated Alcohols

, 2020
The Suzuki-Miyaura reaction is one of the most powerful tools for the formation of carbon-carbon bonds in organic synthesis. The utilization of alcohols in this powerful reaction is a challenging task.
Ruchirawat, Somsak, Akkarasamiyo, Sunisa,, Ploypradith, Poonsaksi, Samec, Joseph S. M.,   +3 more
core   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Stereoselective synthesis towards (+)-trans-kumausyne employing vinylogous Mukaiyama type reaction on an α-chloro sulfide

, 2020
A stereoselective synthesis towards (+)-trans-kumausyne is disclosed. The key steps of the synthesis include stereoselective C-C formation employing vinylogous Mukaiyama type reaction of an α-chloro sulfide with 2-trimethylsiloxy furan and base-catalyzed
Sadagopan, Raghavan ; CSIR-IICT, Chowhan, L Raju ; Department of Organic Synthesis and Process Chemistry, Indian Institute of Chemical Technology, Hyderabad 500 007, India School of Chemistry, University of Hyderabad, Hyderabad 500 046, India   +1 more
core   +2 more sources

Identification of a novel type of spacer element required for imprinting in fission yeast [PDF]

, 2011
Asymmetrical segregation of differentiated sister chromatids is thought to be important for cellular differentiation in higher eukaryotes. Similarly, in fission yeast, cellular differentiation involves the asymmetrical segregation of a chromosomal ...
Suha Sayrac, Sonya Vengrova, Dalgaard Jacob Z., Godfrey Emma L., Godfrey, Emma L., Vengrova, Sonya, Jacob Z. Dalgaard, Sayrac, Suha, Emma L Godfrey, Emma L. Godfrey, Dalgaard, Jacob Z., Jacob Z Dalgaard, Sayrac Suha, Vengrova Sonya   +13 more
core   +2 more sources

Chemical Synthesis of Re-type Lipopolysaccharide.

Trends in Glycoscience and Glycotechnology, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source