Results 81 to 90 of about 3,829,488 (297)

Type Synthesis of Variable Compression Ratio Engine Mechanisms

open access: yesApplied Sciences, 2020
Type synthesis of two-degrees-of-freedom (DOF) planar mechanisms has been carried out using graph theory to determine the possible kinematic structures of variable compression ratio (VCR) engine mechanisms with two to three independent loops, and has ...
Young Kwang Mo   +4 more
doaj   +1 more source

mTORC1 mediates fiber type-specific regulation of protein synthesis and muscle size during denervation

open access: yesCell Death Discovery, 2021
Skeletal muscle denervation occurs in diverse conditions and causes severe muscle atrophy. Signaling by mammalian target of rapamycin complex 1 (mTORC1) plays a central role in the maintenance of skeletal muscle mass by regulating net protein balance ...
Jae-Sung You   +4 more
doaj   +1 more source

Sharp measure contraction property for generalized H-type Carnot groups [PDF]

open access: yes, 2017
We prove that H-type Carnot groups of rank $k$ and dimension $n$ satisfy the $\mathrm{MCP}(K,N)$ if and only if $K\leq 0$ and $N \geq k+3(n-k)$. The latter integer coincides with the geodesic dimension of the Carnot group.
Bonfiglioli A.   +4 more
core   +3 more sources

Chemical Synthesis of Re-type Lipopolysaccharide.

open access: yesTrends in Glycoscience and Glycotechnology, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Compositional synthesis of discrete event systems via synthesis equivalence [PDF]

open access: yes, 2008
A two-pass algorithm for compositional synthesis of modular supervisors for largescale systems of composed finite-state automata is proposed. The first pass provides an efficient method to determine whether a supervisory control problem has a solution ...
Flordal, Hugo, Malik, Robi
core   +2 more sources

The initial mass function of early-type galaxies [PDF]

open access: yes, 2009
We determine an absolute calibration of the initial mass function (IMF) of early-type galaxies, by studying a sample of 56 gravitational lenses identified by the SLACS Survey.
Adam S. Bolton   +39 more
core   +4 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Photocontrolled Synthesis of N-Type Conjugated Polymers

open access: yesAngewandte Chemie International Edition, 2019
Current approaches to synthesize π-conjugated polymers are dominated by thermally driven, transition metal-mediated methods. Herein we show that electron-deficient Grignard monomers readily polymerize under visible light irradiation at room temperature in the absence of a catalyst.
Eliot F. Woods   +2 more
openaire   +4 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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