Results 51 to 60 of about 7,163,146 (192)

Safety and efficacy of subcutaneous and intradermal polycaprolactone / carboxymethyl cellulose gel injections

Materials & Design
Objective: There is a gradual shift towards injecting diluted injectable collagen biostimulators (ICBs) into the dermis to achieve a smaller drug dosage but stronger stimulation of collagen regeneration.
Xianglei Wu, Qirui Wang, Xiaoxi Lin, Xue Wang, Danru Wang   +4 more
doaj   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

The cytokine milieu of bullous pemphigoid: Current and novel therapeutic targets

Frontiers in Medicine, 2023
Bullous pemphigoid (BP) is the most common autoimmune bullous disease, characterized by severe pruritus and skin blistering. The loss of tolerance against Collagen XVII, also referred to as BP180, is the main pathogenic event of BP, leading to production
Roberto Maglie, Farzan Solimani, Farzan Solimani, Dario Didona, Carlo Pipitò, Emiliano Antiga, Giovanni Di Zenzo   +6 more
doaj   +1 more source

Two‐year follow‐up of postcommercialisation cohort of 100 bridge‐enhanced anterior cruciate ligament restorations shows low retear rate and good patient‐reported outcomes

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose To review adverse events and outcomes 2 years postoperatively from the Bridge Enhanced anterior cruciate ligament (ACL) Restoration (BEAR) procedure in the first 100 subjects of the Bridge registry, a postcommercialisation prospective cohort. Methods Technique modifications (repair and bridging suture type, femoral and tibial fixation),
Jocelyn Wittstein, Sabrina Strickland, Andreas Gomoll, Seth Sherman, Brian Lau, Dean Taylor, Dennis Kramer, Sean Keyes, Alexander K. Meininger, Marc Pietropaoli, Sean McMillan, Jacqueline Brady   +11 more
wiley   +1 more source

Type XVII collagen interacts with the aPKC‐PAR complex and maintains epidermal cell polarity [PDF]

Experimental Dermatology, 2020
AbstractType XVII collagen (COL17) is a transmembrane protein expressed in the basal epidermis. COL17 serves as a niche for epidermal stem cells, and although its reduction has been implicated in altering cell polarity and ageing of the epidermis, it is unknown how COL17 affects epidermal cell polarity.
Mika Watanabe, Hideyuki Kosumi, Shin‐Ichi Osada, Shota Takashima, Yunan Wang, Wataru Nishie, Tsukasa Oikawa, Tomonori Hirose, Hiroshi Shimizu, Ken Natsuga   +9 more
openaire   +3 more sources

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

IL-13 mediates collagen deposition via STAT6 and microRNA-135b: a role for epigenetics [PDF]

, 2016
Systemic sclerosis is an autoimmune connective tissue disease in which T cells play a prominent role. We and others have previously demonstrated a role for T cell-derived IL-13 in mediating the induction of collagen in dermal fibroblasts and that ...
van Laar, Jacob, Van Laar, Jacob M., O'Reilly, Steven, Fullard, Nicola, Ciechomska, Marzena, Przyborski, Stefan, van Laar, J.M., O’Reilly, S., Fullard, N., Przyborski, S., Ciechomska, M.   +10 more
core   +2 more sources

Similar Ehlers–Danlos Syndrome Profiles Produced by Variants in Multiple Collagen Genes

DNA
Background: Despite increased attention to double-jointedness or joint hypermobility as seen in connective tissue dysplasias like Ehlers–Danlos syndrome, improved clinical DNA correlations are needed to reduce decadal delays in diagnosis.
Sahil S. Tonk, Golder N. Wilson
doaj   +1 more source

Impact of Chelators on FAC Following Interaction With NaOCl: A Focused Evidence Synthesis Based on a Systematic Search

Australian Endodontic Journal, EarlyView.
ABSTRACT This systematic review following PRISMA guidelines evaluated the effects of endodontic chelators on free available chlorine (FAC) in sodium hypochlorite (NaOCl), with emphasis on the influence of concentration, contact time, temperature, and pH. Risk of bias was assessed using the Quality Assessment Tool for In Vitro Studies (QUIN).
Hinrich Meijer, Louise Franchina, Poonam Nagarani, Roy George   +3 more
wiley   +1 more source

COL17A1 editing via homology-directed repair in junctional epidermolysis bullosa

Frontiers in Medicine, 2022
BackgroundEpidermolysis bullosa (EB), a severe genetic disorder characterized by blister formation in skin, is caused by mutations in genes encoding dermal-epidermal junction proteins that function to hold the skin layers together.
Igor Petković, Johannes Bischof, Thomas Kocher, Oliver Patrick March, Bernadette Liemberger, Stefan Hainzl, Dirk Strunk, Anna Maria Raninger, Heide-Marie Binder, Julia Reichelt, Christina Guttmann-Gruber, Verena Wally, Josefina Piñón Hofbauer, Johann Wolfgang Bauer, Ulrich Koller   +14 more
doaj   +1 more source