Results 71 to 80 of about 2,607 (202)

The Effects of Sodium Dichloroisocyanurate and Calcium Hydroxide as Intracanal Medicaments on Microhardness and Fracture Resistance of Dentin: An In Vitro Study

Clinical and Experimental Dental Research, Volume 12, Issue 1, February 2026.
ABSTRACT Objectives The aim of this study was to evaluate the effect of sodium dicholoroisocyanurate (NaDCC) as intracanal medicament on the dentin microhardness and fracture resistance of teeth compared to calcium hydroxide (CH). Material and Methods Root canals of mandibular premolars (n = 153) were instrumented and randomized into two treatment ...
Fereshte Sobhnamayan, Alireza Adl, Negin Firouzi, Saeed Moravej, Samina Gavahianjahromi   +4 more
wiley   +1 more source

Pathogenic Variants in Mennonites From Southern Brazil: Implications for Preventive Measures in Public Health

Clinical Genetics, Volume 109, Issue 2, Page 266-276, February 2026.
In 325 exomes of South Brazilian Mennonites, we identified 23 pathogenic variants (P) and 27 likely P, with founder effects identified for 96% of P, whose frequencies differed from non‐Finnish Europeans, Amish, and Brazilian populations. ABSTRACT The Mennonite population has a unique history of 500 years of genetic isolation shaped by at least three ...
Luiza Beatriz Mayer de Lima, Eduardo Delabio Auer, Isabela Dall’Oglio Bucco, Valéria Bumiller‐Bini Hoch, Priscila Ianzen dos Santos, Fabiana L. Lopes, Alan Shuldiner, Emilton Lima Júnior, Angelica Beate Winter Boldt   +8 more
wiley   +1 more source

Checkpoint Inhibition May Trigger the Rare Variant of Anti-LAD-1 IgG-Positive, Anti-BP180 NC16A IgG-Negative Bullous Pemphigoid

Frontiers in Immunology, 2019
Bullous pemphigoid (BP) is an autoimmune blistering skin disease characterized by an autoimmune response to type XVII collagen (BP180). The generation of anti-BP180-NC16A IgG autoantibodies is considered to be central to the pathogenesis of BP, in part ...
Christian D. Sadik, Ewan A. Langan, Victoria Grätz, Detlef Zillikens, Patrick Terheyden   +4 more
doaj   +1 more source

Aspirin-exacerbated respiratory disease is associated with variants in filaggrin, epithelial integrity, and cellular interactions

Journal of Allergy and Clinical Immunology: Global
Background: Previous studies have determined that up to 6% of patients with aspirin-exacerbated respiratory disease (AERD) have family history of AERD, indicating a possible link with genetic polymorphisms.
Elina Jerschow, MD, MSc, Robert Dubin, PhD, Chien-Chang Chen, PhD, Alex iAkushev, MSc, Esha Sehanobish, PhD, Mohammad Asad, PhD, Sergio E. Chiarella, MD, Steven A. Porcelli, MD, John Greally, DMed, PhD   +8 more
doaj   +1 more source

Lichen Planus Pemphigoides: From Lichenoid Inflammation to Autoantibody-Mediated Blistering

Frontiers in Immunology, 2019
Lichen planus pemphigoides (LPP) is a very rare autoimmune sub-epidermal blistering disease associated with lichenoid skin changes. Initially thought to be a mere variant of more common inflammatory dermatoses, particularly Bullous Pemphigoid (BP) or ...
Franziska Hübner, Ewan A. Langan, Ewan A. Langan, Andreas Recke, Andreas Recke   +4 more
doaj   +1 more source

Weekly Intraperitoneal Injection of Tamoxifen in an Inducible In Vivo Model of Junctional Epidermolysis Bullosa Generates Early and Advanced Disease Phenotypes

JID Innovations
Junctional epidermolysis bullosa caused by loss-of-function variants in genes encoding the skin basement membrane proteins laminin 332, type XVII collagen, or integrin α6β4 affects patients from birth with severe blistering, eventually leading to ...
Eleri Mai Jones, Priya Garcha, Monique Aumailley, Edel Anne O’Toole, Emanuel Rognoni, Matthew Caley   +5 more
doaj   +1 more source

State-of-the-art diagnosis of autoimmune blistering diseases

Frontiers in Immunology
Autoimmune blistering disorders (AIBDs) are a heterogeneous group of approximately a dozen entities comprising pemphigus and pemphigoid disorders and dermatitis herpetiformis.
Nina van Beek, Maike M. Holtsche, Ingeborg Atefi, Henning Olbrich, Marie J. Schmitz, Jasper Pruessmann, Artem Vorobyev, Enno Schmidt, Enno Schmidt   +8 more
doaj   +1 more source

Evaluation of Cacumen Platycladi Extract for Hair Loss Prevention: Mechanisms, Efficacy, and Clinical Application

Cosmetics
Hair loss is a prevalent condition with various causes, and effective treatments are in high demand. Cacumen Platycladi (Platycladus orientalis leaves), a traditional Chinese medicine, has been historically used to prevent hair loss.
Xue-Dong Bai, Yu-Chen Liu, Hong-Yun Zhao, Yi-Zhou Luo, Li-Jun Xu, Feng Luo   +5 more
doaj   +1 more source

High Index Values of Enzyme-Linked Immunosorbent Assay for BP180 at Baseline Predict Relapse in Patients With Bullous Pemphigoid

Frontiers in Medicine, 2018
Bullous pemphigoid (BP) presenting with erythema plaques and tense blisters is the most frequent autoimmune bullous disease. Immunologically, BP is characterized by the presence of circulating anti-epidermal basement membrane zone (BMZ) antibodies.
Hiroshi Koga, Kwesi Teye, Norito Ishii, Chika Ohata, Takekuni Nakama   +4 more
doaj   +1 more source

Identifying six single nucleotide variants in the COL17A1 gene that alter RNA splicing: database analysis and minigene assays

Scientific Reports
Collagen type XVII alpha 1 chain (COL17A1) is a protein in the collagen family crucial for maintaining the integrity of skin and epithelial tissues. It is also vital for enamel formation and plays a significant role in the differentiation of ameloblasts.
Yingfei Shao, Ran Zhang
doaj   +1 more source