Results 191 to 200 of about 1,001,494 (307)

TPST2-mediated tyrosine sulfation orchestrates porcine preimplantation development. [PDF]

open access: yesBMC Biol
Gao J   +11 more
europepmc   +1 more source

In Situ Characterisation of Hydrogels via Dynamic Interface Printing

open access: yesAdvanced Science, EarlyView.
ABSTRACT Hydrogels have become pivotal materials for tissue engineering, robotics, biomedical devices, and sensing applications due to their diverse material compositions and tunable mechanical properties. While significant effort has focused on developing novel manufacturing approaches such as extrusion bioprinting and light‐based fabrication methods,
Callum Vidler   +2 more
wiley   +1 more source

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1980
T. Hunter, B. Sefton
semanticscholar   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

open access: yesAdvanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong   +5 more
wiley   +1 more source

Protein tyrosine phosphatase inactivation by electrophilic tyrosine modification. [PDF]

open access: yesChem Sci
Ware ML   +9 more
europepmc   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

open access: yesAdvanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin   +17 more
wiley   +1 more source

Phospho-Proteomics Identifies D-Group MAP Kinases as Substrates of the <i>Arabidopsis</i> Tyrosine Phosphatase RLPH2. [PDF]

open access: yesPlant Direct
Labandera AM   +8 more
europepmc   +1 more source

Real‐Time Visualization of Isoform‐Specific RAF‐KRAS Interactions in Living Cells Using FRET‐BRET Hybrid Biosensors

open access: yesAdvanced Science, EarlyView.
Hybrid FRET–BRET biosensors were developed to monitor RAF–KRAS interactions in living cells. These sensors enable real‐time visualization of interaction dynamics, quantitative spectral analysis, and validation of mutation‐selective inhibitors, providing a versatile platform for probing KRAS regulation and therapeutic responses. ABSTRACT The RAS–RAF–MEK–
Jeong‐Min Go   +12 more
wiley   +1 more source

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