Results 221 to 230 of about 1,172,839 (311)

ON THE PREPARATION OF TYROSINE [PDF]

Journal of Biological Chemistry, 1913
openaire   +1 more source

Azabicyclo[1.1.0]butyl‐Substituted Sulfonimidoyl Fluoride: Electrophilic Hub Bridging Late‐Stage Azetidine Incorporation with Sufex Chemistry

Advanced Synthesis &Catalysis, EarlyView.
GA: Strained small motifs and SuFEx hubs are of increasing importance in drug discovery to enable efficient late‐stage functionalization. Here, the synthesis of bench‐stable azabicyclo[1.1.0]butyl‐substituted sulfonimidoyl fluoride as an electrophilic hub with dual activation mode is reported.
Defne Serbetci, Philipp Natho, Ernesto Mesto, Emanuela Schingaro, Marco Colella, Renzo Luisi   +5 more
wiley   +1 more source

Nitisinone desensitization protocol, case report of hereditary Tyrosinemia type 1 with successful treatment and outcomes. [PDF]

Orphanet J Rare Dis
Vallejo M, Villarreal V, Guardiola MA, Bachiller W, Moreno M, Vargas P, López LJ.   +6 more
europepmc   +1 more source

Synthesis of Amidines Via P(III)/P(V)O Redox Catalyzed In Situ Formation of Imidoyl Chlorides From Amides

Advanced Synthesis &Catalysis, EarlyView.
A series of amidines are prepared via PIII/PVO redox catalyzed in situ formation of imidoyl chlorides from amides. The desired products are obtained in good to excellent yields. Moreover, the protocol is applied to the synthesis of Erlotinib. Amidines are a ubiquitous class of bioactive compounds found in a wide variety of natural products; thus ...
Viktorija Medvarić, Jan Paradies, Thomas Werner   +2 more
wiley   +1 more source

3,4,5-Trifluorophenyldiazonium-A Unique Radical Source for the Visible Light Induced, Catalyst-Free Arylation of Tyrosine Residues in Peptides. [PDF]

Chemistry
Kuschow MK, Troeger DR, Schuster LS, Bock L, Zähnle LA, Heinrich MR.   +5 more
europepmc   +1 more source

Ultrasensitive Detection of FKBP12 Using a Synthetic Receptor‐Functionalized QCM Nanoplatform

Advanced Sensor Research, EarlyView.
A reusable nanosensor platform for ultralow FKBP12 detection in physiological fluids is presented. Combining a gold‐coated QCM with a custom‐designed receptor in a self‐assembled monolayer, the device achieves picomolar sensitivity and high selectivity.
Martina Tozzetti, Maria Raffaella Martina, Giacomo Lucchesi, Kristian Vasa, Ahtsham Ishaq, Laura Marsili, Piero Procacci, Stefano Menichetti, Gabriella Caminati   +8 more
wiley   +1 more source

A twist in the tale: shifting from covalent targeting of a tyrosine in JAK3 to a lysine in MK2. [PDF]

RSC Med Chem
Hillebrand L, Wang G, Rasch A, Masberg B, Chaikuad A, Kronenberger T, Günther E, Forster M, Poso A, Lämmerhofer M, Laufer SA, Knapp S, Gehringer M.   +12 more
europepmc   +1 more source

Insect‐Microbe‐Based Laccase: Untapped Natural Resource for Industrial and Biotechnological Applications

Advanced Sustainable Systems, EarlyView.
The insect‐microbe interplay fulfills a key ecological role involving the degradation of ligninocellulose biomass. This is coordinated by the secretion of different kinds of proteins, of which ligninolytic enzymes, such as laccases (Lacs), are of prime importance.
Michael Dare Asemoloye, Adeyinka Michael Gbadebo, Tunde Sheriffdeen Bello, Olumayowa Mary Olowe, Akinlolu Olalekan Akanmu, Marta Elisabetta Eleonora Temporiti, Adeyinka Odebode, Segun Oladiran Babarinde, Tsigereda Weldemichael, Leonard Chitongo, Solveig Tosi, Mario Andrea Marchisio   +11 more
wiley   +1 more source

The effect of Zuogui-Jiangtang-Yishen decoction on the intestinal flora's response to L-α-phosphatidylcholine and L-tyrosine in patients with diabetic kidney disease: an <i>in vitro</i> study. [PDF]

Front Pharmacol
Yin Y, Zhao C, Xiang Q, Li Z, Liu X, Hu C, Yu R.   +6 more
europepmc   +1 more source