Results 31 to 40 of about 880,315 (306)

Performance of piglets in response to the standardized ileal digestible phenylalanine and tyrosine supply in low-protein diets

Animal, 2014
Reducing the CP level of the diet allows for a reduction in N excretion without limiting performance as long as the amino acid (AA) requirements are covered. The availability of crystalline AA has permitted for a considerable reduction in the CP level of
M. Gloaguen, N. Le Floc’h, Y. Primot, E. Corrent, J. van Milgen   +4 more
doaj   +1 more source

Cooperativity of Glucocorticoid Response Elements Located Far Upstream of the Tyrosine Aminotransferase Gene [PDF]

, 1987
Two glucocorticoid response elements (GREs) located 2.5 kb upstream of the transcription initiation site of the tyrosine aminotransferase gene were identified by gene transfer experiments and shown to bind to purified glucocorticoid receptor.
Strähle, Uwe, Boshart, Michael, Schmid, Wolfgang, Miksicek, Richard, Jansen, Hans-Michael, Gloss, Bernd, Schlitz, Günther, Stewart, Francis   +7 more
core   +1 more source

Effect of large neutral amino acids treatment on blood phenylalanine, tyrosine, and tryptophan levels in adolescent and young adult PKU patients

Trends in Pediatrics
Objective: We aimed to evaluate the change in phenylalanine (Phe), Tyrosine (Tyr), and Tryptophan (Trp) blood levels in classical PKU patients treated with large neutral amino acids (LNAA) supplementation.
Fehime Erdem, Ebru Canda, Havva Yazıcı, Yasemin Atik Altınok, Merve Yoldaş Çelik, Ayşe Yüksel Yanbolu, Sema Kalkan Uçar, Sara Habif, Mahmut Çoker   +8 more
doaj   +1 more source

Serum tryptophan, kynurenine, phenylalanine, tyrosine and neopterin concentrations in 100 healthy blood donors

Pteridines, 2015
Formation of neopterin, a biomarker of the activated human immune system, is linked with tryptophan (TRP) and phenylalanine (PHE) metabolism. To obtain normal values, in this study, serum concentrations of neopterin as well as of TRP, PHE and their ...
Geisler Simon, Mayersbach Peter, Becker Kathrin, Schennach Harald, Fuchs Dietmar, Gostner Johanna M.   +5 more
doaj   +1 more source

Phosphorylation of (Ser 291) in the linker insert of Syk negatively regulates ITAM signaling in platelets

Platelets
Receptor-induced tyrosine phosphorylation of spleen tyrosine kinase (Syk) has been studied extensively in hematopoietic cells. Metabolic mapping and high-resolution mass spectrometry, however, indicate that one of the most frequently detected ...
Carol Dangelmaier, Hymavathi Reddy Vari, Dhruv N Vajipayajula, Manal Elzoheiry, Monica Wright, Ashvin Iyer, Alexander Y Tsygankov, Satya P Kunapuli   +7 more
doaj   +1 more source

Hawkinsinuria With Direct Hyperbilirubinemia in Egyptian-Lebanese Boy

Frontiers in Pediatrics, 2019
Tyrosinemia type III is the rarest type of tyrosinemia, because of a mutation in 4-OH-phenylpyruvate dioxygenase (HPD). This causes two different types of diseases with different modes of inheritance: tyrosinemia type III and hawkinsinuria. Hawkinsinuria
Hassan El Khatib, Bilal Asaad, Aisha Zaylaa, Farah Awad, Mariam Sbeity, Sirin Mneimneh, Georges Haber, Zeina Naja, Mariam Rajab   +8 more
doaj   +1 more source

Large-scale structural analysis of the classical human protein tyrosine phosphatome. [PDF]

, 2009
Protein tyrosine phosphatases (PTPs) play a critical role in regulating cellular functions by selectively dephosphorylating their substrates. Here we present 22 human PTP crystal structures that, together with prior structural knowledge, enable a ...
Lee, W.H., Ugochukwu, E., Savitsky, P, King, Oliver N F, Ugochukwu, Emilie, Knapp, S., Alfano, I, Müller, S, Filippakopoulos, Panagis, Barr, AJ, King, ON, King, O.N.F., Müller, Susanne, Savitsky, P., Muller, S., Filippakopoulos, P., Lee, Wen Hwa, Alfano, I., Knapp, Stefan, Ugochukwu, E, Alfano, Ivan, King, Oliver N.F., Barr, Alastair J., Barr, A.J., Burgess-Brown, N.A., Burgess-Brown, Nicola, Barr, Alastair J, Lee, WH, Savitsky, Pavel, Burgess-Brown, Nicola A., Burgess-Brown, Nicola A   +30 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Detection of tyrosine phosphorylated proteins in trichinella spiralis L1 larvae

Parasite, 2001
Western-blotting analysis showed the presence of tyrosine phosphorylated proteins in crude extracts of T. spiralis larvae and these phosphorylated proteins were located by immunofluorescence on the striations of the larval cuticle.
Allegretti S., Beaumont V., Robert-Gangneux F., Creuzet C., Roisin M.P., Dupouy-Camet J.   +5 more
doaj   +1 more source

Determination of Tyrosine in Artificial Urine Using a Screen-Printed Electrode Modified with tetrathiafulvalene-tetracyanoquinodimethane/ionic Liquid Conductive Gel

International Journal of Electrochemical Science, 2020
In this study, the screen-printed electrode (SPE) was developed for detection of tyrosine based on tetrathiafulvalene-tetracyanoquinodimethane/ionic liquid conductive gel.
Xiaoping Zhang, Xiatong Li, Xinyue Pei, Ting Shu, Qing Min, Shi Wang   +5 more
doaj   +1 more source