Results 11 to 20 of about 672,412 (218)

High intensity interval training exercise increases dopamine D2 levels and modulates brain dopamine signaling

Frontiers in Public Health, 2023
BackgroundPrevious research has outlined the health benefits of exercise including its therapeutic potential for substance use disorders (SUD). These data have already been utilized and it is now common to find exercise as part of SUD treatment and ...
John Tyler, John Tyler, Madeline Podaras, Madeline Podaras, Brittany Richardson, Brittany Richardson, Nicole Roeder, Nicole Roeder, Nikki Hammond, John Hamilton, Kenneth Blum, Mark Gold, David A. Baron, Panayotis K. Thanos, Panayotis K. Thanos   +14 more
doaj   +1 more source

Curcumin-driven reprogramming of the gut microbiota and metabolome ameliorates motor deficits and neuroinflammation in a mouse model of Parkinson’s disease

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundParkinson’s disease (PD) is a common neurodegenerative disorder, accompanied by motor deficits as well as gastrointestinal dysfunctions.
Can Cui, Yingying Han, Hongxia Li, Hongxiang Yu, Bei Zhang, Gang Li   +5 more
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The Vav GEF Family: An Evolutionary and Functional Perspective

Cells, 2019
Vav proteins play roles as guanosine nucleotide exchange factors for Rho GTPases and signaling adaptors downstream of protein tyrosine kinases. The recent sequencing of the genomes of many species has revealed that this protein family originated in ...
Sonia Rodríguez-Fdez, Xosé R. Bustelo
doaj   +1 more source

Hierarchical graphene oxide-Ni3S2 quantum dots nanocomposites modified glassy carbon electrode for electrochemical detection of dopamine and tyrosine

Frontiers in Materials, 2023
A facile synthetic strategy is demonstrated to generate nickel sulfide quantum dots (Ni3S2). The thus formed Ni3S2 quantum dots are assembled onto exfoliated graphene oxide sheets hydrothermally to form nickel sulfide-graphene oxide nanocomposite ...
M. Hasheena, A. Ratnamala, M. Noorjahan, G. Deepthi Reddy, Gousia Begum   +4 more
doaj   +1 more source

Effects of Dietary Phenylalanine and Tyrosine Supplements on the Chronic Stress Response in the Seabream (Sparus aurata)

Frontiers in Physiology, 2022
The increase of aquaculture production is associated with a growing interest in improving physiological status and welfare in fish. For this reason, the search for strategies for mitigating stress has been intensified, with one of these strategies being ...
Natalia Salamanca, Oscar Moreno, Inmaculada Giráldez, Emilio Morales, Ignacio de la Rosa, Marcelino Herrera, Marcelino Herrera   +6 more
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Increased prevalence of Parkinson's disease in alkaptonuria

JIMD Reports, 2023
Amongst a cohort of 88 alkaptonuria (AKU) patients attending the United Kingdom National Alkaptonuria Centre (NAC), four unrelated patients had co‐existing Parkinson's disease (PD).
Lakshminarayan Ranganath, Milad Khedr, Anna M. Milan, Andrew S. Davison, Brendan P. Norman, Mirian C. H. Janssen, Edward Lock, George Bou‐Gharios, James A. Gallagher   +8 more
doaj   +1 more source

L-DOPA Trends in Different Tissues at Early Stages of Vicia faba Growth: Effect of Tyrosine Treatment

Applied Sciences, 2018
The nonprotein amino acid Levo-3,4-dihydroxyphenylalanine (L-DOPA) has insecticidal, allelochemical, and antiparkinsonian effects. The aim of this research was to assess L-DOPA content in different tissues of Vicia faba (cv.
Claudia A. Oviedo-Silva, Mhartyn Elso-Freudenberg, Mario Aranda-Bustos   +2 more
doaj   +1 more source

Performance of piglets in response to the standardized ileal digestible phenylalanine and tyrosine supply in low-protein diets

Animal, 2014
Reducing the CP level of the diet allows for a reduction in N excretion without limiting performance as long as the amino acid (AA) requirements are covered. The availability of crystalline AA has permitted for a considerable reduction in the CP level of
M. Gloaguen, N. Le Floc’h, Y. Primot, E. Corrent, J. van Milgen   +4 more
doaj   +1 more source

Effect of large neutral amino acids treatment on blood phenylalanine, tyrosine, and tryptophan levels in adolescent and young adult PKU patients

Trends in Pediatrics
Objective: We aimed to evaluate the change in phenylalanine (Phe), Tyrosine (Tyr), and Tryptophan (Trp) blood levels in classical PKU patients treated with large neutral amino acids (LNAA) supplementation.
Fehime Erdem, Ebru Canda, Havva Yazıcı, Yasemin Atik Altınok, Merve Yoldaş Çelik, Ayşe Yüksel Yanbolu, Sema Kalkan Uçar, Sara Habif, Mahmut Çoker   +8 more
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Serum tryptophan, kynurenine, phenylalanine, tyrosine and neopterin concentrations in 100 healthy blood donors

Pteridines, 2015
Formation of neopterin, a biomarker of the activated human immune system, is linked with tryptophan (TRP) and phenylalanine (PHE) metabolism. To obtain normal values, in this study, serum concentrations of neopterin as well as of TRP, PHE and their ...
Geisler Simon, Mayersbach Peter, Becker Kathrin, Schennach Harald, Fuchs Dietmar, Gostner Johanna M.   +5 more
doaj   +1 more source