Results 71 to 80 of about 1,086,674 (386)
Tyrosine Phosphorylation Regulates Maturation of Receptor Tyrosine Kinases [PDF]
Molecular and Cellular Biology, 2005 Constitutive activation of receptor tyrosine kinases (RTKs) is a frequent event in human cancer cells. Activating mutations in Fms-like tyrosine kinase 3 (FLT-3), notably, internal tandem duplications in the juxtamembrane domain (FLT-3 ITD), have been causally linked to acute myeloid leukemia.
Hubert Serve +5 more
openaire +3 more sources
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Frontiers in Materials, 2023 A facile synthetic strategy is demonstrated to generate nickel sulfide quantum dots (Ni3S2). The thus formed Ni3S2 quantum dots are assembled onto exfoliated graphene oxide sheets hydrothermally to form nickel sulfide-graphene oxide nanocomposite ...
M. Hasheena +4 more
doaj +1 more source
Oral Branched-Chain Amino Acid Supplements That Reduce Brain Serotonin During Exercise in Rats Also Lower Brain Catecholamines [PDF]
, 2013 Exercise raises brain serotonin release and is postulated to cause fatigue in athletes; ingestion of branched-chain amino acids (BCAA), by competitively inhibiting tryptophan transport into brain, lowers brain tryptophan uptake and serotonin synthesis ...
Choi, Sujean +3 more
core +1 more source
The formation of m-tyrosine and o-tyrosine in rats.
Chemical and Pharmaceutical Bulletin, 1984 Intraperitoneal administration of L-phenylalanine in rats gave rise to three hydroxylated products which were identified by high performance liquid chromatography as p-tyrosine, m-tyrosine and o-tyrosine.
Susumu Ishimitsu +2 more
openaire +4 more sources
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Liquid-liquid Phase Separation as the Second Step of Complex Coacervation [PDF]
arXiv, 2020 Liquid liquid phase separation (LLPS) mediated by pi-cation bonds between tyrosine and arginine residues are of biological importance. To understand the interactions between proteins in the condensed phase in close analogy to complex coacervation, we run multiple umbrella calculations between oligomers containing tyrosine (pY) and arginine (pR).
arxiv
Isoform- and Cell-Specific Function of Tyrosine Decarboxylase in the Drosophila Malpighian Tubule [PDF]
, 2009 The biogenic amine tyramine (TA) is a potent diuretic factor when applied to the Malpighian tubule (MT) of Drosophila melanogaster, stimulating both urine production and transepithelial chloride conductance.
Blumenthal, Edward M
core +1 more source
Role of tyrosine M210 in the initial charge separation of reaction centers of Rhodobacter sphaeroides [PDF]
, 1990 Femtosecond spectroscopy was used in combination with site-directed mutagenesis to study the influence of tyrosine M210 (YM210) on the primary electron transfer in the reaction center of Rhodobacter sphaeroides.
Allen J. P. +25 more
core +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source