Results 191 to 200 of about 1,776,183 (353)

Identification of a Novel Series of Potent TrkA Receptor Tyrosine Kinase Inhibitors [PDF]

, 2012
Stéphane Raeppel, Frédéric Gaudette, Hannah Nguyen, Normand Beaulieu, James Wang, Christiane R. Maroun, Jeffrey M. Besterman, Arkadii Vaisburg   +7 more
openalex   +1 more source

Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor.

New England Journal of Medicine, 2001
H. Joensuu, P. Roberts, M. Sarlomo‐Rikala, Leif C. Andersson, P. Tervahartiala, David A. Tuveson, David A. Tuveson, S. Silberman, R. Capdeville, S. Dimitrijević, B. Druker, G. Demetri   +11 more
semanticscholar   +1 more source

Pigment Epithelium‐Derived Factor Deficiency Impairs Hippocampal Glutamate Homeostasis and Cognitive Function by Downregulating Astrocytic GLT‐1

Advanced Science, EarlyView.
The chronic glutamate‐induced excitotoxicity hypothesis has profoundly informed the therapeutic strategies employed in Alzheimer’s disease (AD). This study shows pigment epithelium‐derived factor (PEDF) regulates astrocytic glutamate transporter‐1 (GLT‐1)‐mediated glutamate homeostasis and cognition. Reduced PEDF correlates with lower Mini‐Mental State
Jin‐Hui Shi, Qi‐Long Tang, Jin‐Hong Wang, Yan‐Lan Long, Sai‐Feng Zhao, Zhen Zhao, Wan‐Ting Xie, Zi‐Ming Li, Hao‐Ming Lu, Tian‐Xiao Gao, Zhen‐Zhen Fang, Ti Zhou, Bo‐Xing Li, Xia Yang, Guo‐Quan Gao, Wei‐Wei Qi   +15 more
wiley   +1 more source

Comparison of the Use of Immune Checkpoint Inhibitor/Tyrosine Kinase Inhibitor and Tyrosine Kinase Inhibitor Alone for Patients With Low Risk Metastatic Renal Cell Carcinoma. [PDF]

In Vivo
Oki M, Ohba K, Mukae Y, Matsuda T, Nakanishi H, Mitsunari K, Matsuo T, Mochizuki Y, Imamura R.   +8 more
europepmc   +1 more source

INCIDENCE OF HEPATITIS B REACTIVATION DURING EGFR TYROSINE KINASE INHIBITORS TREATMENT IN NON‐SMALL‐CELL LUNG CANCER PATIENTS [PDF]

, 2018

openalex   +1 more source

Skin problems and EGFR-tyrosine kinase inhibitor.

Japanese Journal of Clinical Oncology, 2016
T. Kozuki
semanticscholar   +1 more source

CircPVT1 Promotes Lung Metastasis and Tumor Progression in Renal Cell Carcinoma by Encoding the cP104aa Peptide and Targeting EIF4A3

Advanced Science, EarlyView.
This study reveals that circPVT1 promotes the renal cell carcinoma lung metastasis and tumor progression through encoding the cP104aa peptide and directly binds with EIF4A3, which jointly regulates the target gene c‐MYC. Abstract Circular RNA (circRNA) plays a pivotal role in the pathogenesis of renal cell carcinoma (RCC).
Houliang Zhang, Tao Tao, Jie Ji, Tonglei Zhao, Si Sun, Lijie Zhang, Jianping Wu, Ming Chen, Shuqiu Chen, Bin Xu, Weipu Mao   +10 more
wiley   +1 more source

Analysis of the Role of the SRC Tyrosine Kinase and Podoplanin in the Process of Entosis. [PDF]

Cancers (Basel)
Gawel AM, Godlewska M, Biały LP, Mlynarczuk-Bialy I.   +3 more
europepmc   +1 more source

Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia

, 2003
S. Maynard, J. Min, J. Merchan, K. Lim, Jianyi Li, S. Mondal, T. Libermann, J. Morgan, F. Sellke, I. Stillman, F. Epstein, V. Sukhatme, S. Karumanchi   +12 more
semanticscholar   +1 more source

Resistance mechanisms for the Bruton's tyrosine kinase inhibitor ibrutinib.

New England Journal of Medicine, 2014
J. Woyach, R. Furman, Ta-Ming Liu, H. Ozer, M. Zapatka, A. Ruppert, L. Xue, Daniel Li, S. Steggerda, M. Versele, S. Dave, Jenny Zhang, A. S. Yilmaz, S. Jaglowski, K. Blum, A. Lozanski, G. Lozanski, D. James, J. Barrientos, P. Lichter, S. Stilgenbauer, J. Buggy, B. Chang, A. Johnson, J. Byrd   +24 more
semanticscholar   +1 more source