Results 191 to 200 of about 1,906,742 (351)

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Biopsy-proven tyrosine kinase inhibitor-associated renal injury: a case series. [PDF]

Clin Kidney J
Lian J, Tian J, Liang S, Xu F, Yang F, Chen D, Zhu X, Zhong Y, Zeng C.   +8 more
europepmc   +1 more source

Supplementary Figure 2 from Systematic Evaluation of Tyrosine Kinase Inhibitors as OATP1B1 Substrates Using a Competitive Counterflow Screen

Thomas Drabison, Mike Boeckman, Yan Yang, Kevin M. Huang, Peter de Bruijn, Mahesh R. Nepal, Josie A. Silvaroli, Anika T. Chowdhury, Eric D. Eisenmann, Xiaolin Cheng, Navjotsingh Pabla, Ron H.J. Mathijssen, Sharyn D. Baker, Shuiying Hu, Alex Sparreboom, Zahra Talebi   +15 more
openalex   +1 more source

THE ROLE OF PREDICTOR PLACENTAL GROWTH FACTOR, SOLUBLE ENDOGLIN, SOLUBLE-FMS-LIKE-TYROSINE KINASE-1 AND PULSATIL UTERINA ARTERIAL INDEX TO PREDICT THE EARLY ONSET OF PREECLAMPSIA

, 2020
Muara Panusunan Lubis
openalex   +2 more sources

ALKALs are in vivo ligands for ALK family receptor tyrosine kinases in the neural crest and derived cells [PDF]

, 2018
Andrey Fadeev, Patricia Mendoza-García, Uwe Irion, Jikui Guan, Kathrin Pfeifer, Stephanie Wiessner, Fabrizio C. Serluca, Ajeet Pratap Singh, Christiane Nüsslein‐Volhard, Ruth H. Palmer   +9 more
openalex   +1 more source

Skin problems and EGFR-tyrosine kinase inhibitor.

Japanese Journal of Clinical Oncology, 2016
T. Kozuki
semanticscholar   +1 more source

Single‐Cell Transcriptomics Reveals FLS2‐Dependent Hypoxia Signaling and ERF13‐Mediated Transcription During flg22‐Triggered Immunity

Advanced Science, EarlyView.
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou, Aizhi Qin, Mengfan Li, Qianli Zhao, Luyao Kong, Lulu Yan, Chunyang Li, Hao Liu, Yinpeng Zhang, Jiani Long, Mengyu Liao, Mengmeng Zhou, Xiaoli Fan, Baozhen Wang, Wenxuan Kang, Shui Wang, Zhixin Liu, Xuwu Sun   +17 more
wiley   +1 more source

Bruton Tyrosine Kinase Inhibitor Ibrutinib and Pericardial Tamponade: A Case Report. [PDF]

Cureus
Baptista M, Soares M, Lima R, Ferreira C, Gregório T.   +4 more
europepmc   +1 more source

VE‐Cadherin–Actin Regulation Promotes Mechanotransduction and Monolayer Maturation Involving a Tension‐Sensitive Intermediate State

Advanced Science, EarlyView.
This study investigates how endothelial monolayers balance cohesion and plasticity during mechanical stimulation. In HUVECs, shear stress induces a tension‐sensitive intermediate state in which junctional VE‐cadherin and actomyosin relaxation levels coordinate actin/integrin remodeling. This rapid, reversible state strengthens cell junctions, preserves
Jonas Franz, Maria Odenthal‐Schnittler, Jan Philip Kipcke, Jochen Seebach, Zahra Labbaf, Franziska Merten, Vesna Bojovic, Muna Taha, Johannes A. Eble, Erez Raz, Milos Galic, Hans Schnittler   +11 more
wiley   +1 more source

Comparison of the Use of Immune Checkpoint Inhibitor/Tyrosine Kinase Inhibitor and Tyrosine Kinase Inhibitor Alone for Patients With Low Risk Metastatic Renal Cell Carcinoma. [PDF]

In Vivo
Oki M, Ohba K, Mukae Y, Matsuda T, Nakanishi H, Mitsunari K, Matsuo T, Mochizuki Y, Imamura R.   +8 more
europepmc   +1 more source