Results 231 to 240 of about 438,950 (335)

Genomics Review of Selective RET Inhibitors Sensitivity in Thyroid Cancer Clinical Trials

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT RET gene is a driver of thyroid cancer (TC) tumorigenesis. The incidence of TC has increased worldwide in the last few decades, both in medullary and follicular‐derived subtypes. Several drugs, including multikinase and selective inhibitors, have been explored.
Sara Gil‐Bernabé, Lucía García‐DeLaFuente, Alejandro García‐Álvarez, Ginesa García‐Rostán, Jaume Capdevila, Jorge Hernando   +5 more
wiley   +1 more source

Bruton's tyrosine kinase inhibitor associated localized extremity edema and erythema. [PDF]

JAAD Case Rep
Meledathu S, Chu P, Feldman T, Goy AH, Rosenstein RK.   +4 more
europepmc   +1 more source

Antipeptide antiserum identifies a widely distributed cellular tyrosine kinase related to but distinct from the c-fps/fes-encoded protein.

, 1986
Ricardo A. Feldman, James P. Tam, Hidesaburô Hanafusa   +2 more
openalex   +1 more source

Evaluation of Bruton's Tyrosine Kinase (BTK) inhibition with alternative doses of ibrutinib in subjects with Chronic Lymphocytic Leukemia (CLL). [PDF]

Cancer Chemother Pharmacol
Ouerdani A, Valenzuela B, Treijtel N, Haddish-Berhane N, Desphande S, Srinivasan S, Smith E, Perez Ruixo JJ.   +7 more
europepmc   +1 more source

Tyrosine kinase catalyzed phosphorylation and inactivation of the inhibitor protein of the cAMP-dependent protein kinase.

, 1987
Scott M. Van Patten, G.J. Heisermann, Heung‐Chin Cheng, Donal A. Walsh   +3 more
openalex   +1 more source

Targeting signaling pathways in neurodegenerative diseases: Quercetin's cellular and molecular mechanisms for neuroprotection

Animal Models and Experimental Medicine, EarlyView.
Quercetin regulates signaling pathways in neurodegenerative diseases, including NF‐κB, sirtuins, and PI3K/Akt. Studies show quercetin improves symptoms and pathology in neurodegenerative models. The study aims to incorporate laboratory research into practical medical treatment, focusing on quercetin's neuroprotective effects and optimal dosage ...
Md. Rezaul Islam, Md. Ibrahim Khalil Al‐Imran, Mehrukh Zehravi, Sherouk Hussein Sweilam, Mohammad Rakib Mortuza, Jeetendra Kumar Gupta, Thukani Sathanantham Shanmugarajan, Kadirvel Devi, Tanuja Tummala, Mohammed Ali Alshehri, Kalirajan Rajagopal, Mohammed Asiri, Irfan Ahmad, Talha Bin Emran   +13 more
wiley   +1 more source

The tyrosine kinase Yes1 is a druggable host factor of HEV. [PDF]

Hepatol Commun
Haase JA, Baheerathan A, Zhang X, Fu RM, Nocke MK, Decker C, Dao Thi VL, Todt D, Neyts J, Kaptein SJF, Steinmann E, Kinast V.   +11 more
europepmc   +1 more source

Isolation and analysis of an Abelson murine leukemia virus-encoded tyrosine-specific kinase produced in Escherichia coli.

, 1985
B Ferguson, M. Lynn Pritchard, John A. Feild, David J. Rieman, Russell Greig, George Poste, Martin Rosenberg   +6 more
openalex   +1 more source

Application of humanized mice in the safety experiments of antibody drugs

Animal Models and Experimental Medicine, EarlyView.
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun, Mengyun Gu, Zixuan Yang, Lei Shi, Liyuan Zhao, Minhui Zheng, Yan Wang, Wei Zhang, Kexin Han, Naping Tang   +9 more
wiley   +1 more source

ACTR10 Overexpression Facilitates the Progression and Tyrosine Kinase Inhibitor Resistance in Hepatocellular Carcinoma. [PDF]

World J Oncol
Luo J, Qin K, He RQ, Li JD, Huang ZG, Yin BT, Wu T, Chen YZ, Qin DY, Luo JY, Wu M, Chi BT, Chen G, Li JJ, Huang YB.   +14 more
europepmc   +1 more source