Results 241 to 250 of about 1,776,183 (353)

The Role of Tyrosine Kinase in Beauty and Skincare: A Comprehensive Review. [PDF]

J Cosmet Dermatol
Li Z.
europepmc   +1 more source

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions.

Proceedings of the National Academy of Sciences of the United States of America, 1992
M. Schaller, C. A. Borgman, B. Cobb, R. Vines, A. ReynoldsT, J. Parsons   +5 more
semanticscholar   +1 more source

Inhibition of Tumor Lipogenesis and Growth by Peptide‐Based Targeting of SREBP Activation

Advanced Science, EarlyView.
A peptide that replicates the amino acid sequence in Insig1/2 loop 1 inhibits the IGF1‐induced interaction between PCK1 and Insig1/2, PCK1‐mediated phosphorylation of Insig1/2, and SREBP activity‐dependent lipid synthesis. Administration of the LNP‐Insig1/2 loop 1 peptide effectively attenuates tumor growth and sensitizes tumors to the antitumor effect
Shudi Luo, Huang Yang, Xiaoming Jiang, Zheng Wang, Xuxiao He, Ying Meng, Shan Li, Min Li, Daqian Xu, Zhengwei Mao, Zhimin Lu   +10 more
wiley   +1 more source

Tyrosine Kinase Inhibitor Treatment of a Patient with Chronic Myeloid Leukemia and Congenital Thrombophilia. [PDF]

Hematol Rep
Herrera-Hernández C, Segura-Diaz A, Stuckey R, López-Rodríguez JF, Gómez-Casares MT.   +4 more
europepmc   +1 more source

Efficacy of a tyrosine kinase inhibitor in idiopathic pulmonary fibrosis.

New England Journal of Medicine, 2011
L. Richeldi, U. Costabel, M. Selman, D. S. Kim, D. Hansell, A. Nicholson, K. Brown, K. Flaherty, P. Noble, G. Raghu, M. Brun, Abhya Gupta, N. Juhel, M. Klüglich, R. D. du Bois   +14 more
semanticscholar   +1 more source

Repurposing Cardiac Glycosides to Potentiate CD47 Blockade through Calreticulin‐mediated Phagocytic Effects for Lung Cancer Treatment

Advanced Science, EarlyView.
Repurposing cardiac glycosides (CGs) significantly strengthens the efficacy of anti‐CD47 antibody for lung cancer treatment by boosting macrophage phagocytosis. This novel combination blocks the “don't eat me” signal and increases dual “eat‐me” signals, Fc‐FcγR and cell surface expression of calreticulin (ecto‐CRT).
Zi‐Han Ye, Wei‐Bang Yu, Mu‐Yang Huang, Yan‐Yan Chen, Le‐Le Zhang, Chung‐Hang Leung, Xiao‐Lei Zhang, Zhenghai Tang, Ting Li, Jin‐Jian Lu   +9 more
wiley   +1 more source

A Novel Allosteric Inhibitor Targeting IMPDH at Y233 Overcomes Resistance to Tyrosine Kinase Inhibitors in Lymphoma. [PDF]

Cancers (Basel)
Pattabiraman N, Lobello C, Rushmore D, Mologni L, Wasik M, Basappa J.   +5 more
europepmc   +1 more source

Supplementary Figure S3 from Tyrosine Kinase Inhibitors Diminish Renal Neoplasms in a Tuberous Sclerosis Model via induction of Apoptosis

Uchenna Unachukwu, Jarrod Sonett, Denzel Woode, Takayuki Shiomi, Kiran Chada, Jeanine D’Armiento   +5 more
openalex   +1 more source

Curcumin Suppresses Janus Kinase-STAT Inflammatory Signaling through Activation of Src Homology 2 Domain-Containing Tyrosine Phosphatase 2 in Brain Microglia [PDF]

, 2003
Hak Yong Kim, Eun Jung Park, Eun-hye Joe, Ilo Jou   +3 more
openalex   +1 more source

Tyrosine phosphorylation of protein kinase complex BAK1/BIK1 mediates Arabidopsis innate immunity

Proceedings of the National Academy of Sciences of the United States of America, 2014
Wenwei Lin, Bo Li, Dongping Lu, Sixue Chen, Ning Zhu, P. He, Libo Shan   +6 more
semanticscholar   +1 more source