Results 81 to 90 of about 205,532 (202)

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Image_9_In vitro DNA Inversions Mediated by the PsrA Site-Specific Tyrosine Recombinase of Streptococcus pneumoniae.TIF

, 2020
Site-specific recombination is a DNA breaking and reconstructing process that plays important roles in various cellular pathways for both prokaryotes and eukaryotes. This process requires a site-specific recombinase and direct or inverted repeats.
Jingwen Li (314020), Sofía Ruiz-Cruz (8597100), Jing-Ren Zhang (271032), Alicia Bravo (4886896), Manuel Espinosa (25471), Juanjuan Wang (1807810)   +5 more
core   +1 more source

In Adult Skeletal Muscles, the Co-Receptors of Canonical Wnt Signaling, Lrp5 and Lrp6, Determine the Distribution and Size of Fiber Types, and Structure and Function of Neuromuscular Junctions

Cells, 2022
Canonical Wnt signaling is involved in skeletal muscle cell biology. The exact way in which this pathway exerts its contribution to myogenesis or neuromuscular junctions (NMJ) is a matter of debate.
Lea Gessler, Christopher Kurtek, Mira Merholz, Yongzhi Jian, Said Hashemolhosseini   +4 more
doaj   +1 more source

Image_7_In vitro DNA Inversions Mediated by the PsrA Site-Specific Tyrosine Recombinase of Streptococcus pneumoniae.TIF

, 2020
Site-specific recombination is a DNA breaking and reconstructing process that plays important roles in various cellular pathways for both prokaryotes and eukaryotes. This process requires a site-specific recombinase and direct or inverted repeats.
Jingwen Li (314020), Sofía Ruiz-Cruz (8597100), Jing-Ren Zhang (271032), Alicia Bravo (4886896), Manuel Espinosa (25471), Juanjuan Wang (1807810)   +5 more
core   +1 more source

Purkinje Cell-Specific Knockout of Tyrosine Hydroxylase Impairs Cognitive Behaviors

Frontiers in Cellular Neuroscience, 2020
Tyrosine hydroxylase (Th) expression has previously been reported in Purkinje cells (PCs) of rodents and humans, but its role in the regulation of behavior is not understood.
Timothy M. Locke, Timothy M. Locke, Hirofumi Fujita, Avery Hunker, Shelby S. Johanson, Martin Darvas, Sascha du Lac, Sascha du Lac, Sascha du Lac, Larry S. Zweifel, Larry S. Zweifel, Erik S. Carlson, Erik S. Carlson   +12 more
doaj   +1 more source

Low‐Concentration Enhancement Effect: Enabling Sensitive Detection of EML4‐ALK Variants via Multiplex RT‐MIRA

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed an optimized multiplex RT‐MIRA assay for the simultaneous detection of EML4‐ALK variants, achieving single‐copy sensitivity. Unexpectedly, during the development of the reaction system, we discovered a “low‐concentration enhancement effect,” where reducing primer or probe concentrations within a specific range markedly improved ...
Xiao‐Dong Ren, Xi‐Yao Luo, Jin‐Mi Li, Xian‐Ge Sun, Jing Lv, Hua‐Liang Xiao, Qiu‐Shi Wang, Hong Wang, Chun‐Yan Wang, Hao‐Zheng Li, Qing Huang   +10 more
wiley   +1 more source

Image_2_In vitro DNA Inversions Mediated by the PsrA Site-Specific Tyrosine Recombinase of Streptococcus pneumoniae.TIF

, 2020
Site-specific recombination is a DNA breaking and reconstructing process that plays important roles in various cellular pathways for both prokaryotes and eukaryotes. This process requires a site-specific recombinase and direct or inverted repeats.
Jingwen Li (314020), Sofía Ruiz-Cruz (8597100), Jing-Ren Zhang (271032), Alicia Bravo (4886896), Manuel Espinosa (25471), Juanjuan Wang (1807810)   +5 more
core   +1 more source

Recombinase-Aided Amplification Combined with Lateral Flow (LF‑RAA) Assay for Rapid AAV Genome Detection

, 2022
Adeno-associated virus (AAV) is a versatile gene vector that is widely used in mammalian research. In basic studies and large-scale AAV production, genetic testing is ubiquitous and routine polymerase chain reaction (PCR)-based tests limit the efficiency
Yong Diao (524165), Ruolan Huang (14266006), Dan Liu (108669), Liyun Zhang (280172), Kun Wang (134525)   +4 more
core   +1 more source

From knowledge to action: the importance of characterizing herbicide resistance mechanisms for implementing management strategies

Pest Management Science, EarlyView.
This review bridges the gap between understanding resistance mechanisms and applying them in weed management, highlighting how mechanistic insights reveal vulnerabilities that can guide more effective control strategies. Abstract Herbicide resistance remains one of the most intensively studied areas in weed science because of its direct consequences ...
Luan Cutti, Eric L. Patterson, Todd A. Gaines, Aldo Merotto   +3 more
wiley   +1 more source

Image_4_In vitro DNA Inversions Mediated by the PsrA Site-Specific Tyrosine Recombinase of Streptococcus pneumoniae.TIF

, 2020
Site-specific recombination is a DNA breaking and reconstructing process that plays important roles in various cellular pathways for both prokaryotes and eukaryotes. This process requires a site-specific recombinase and direct or inverted repeats.
Jingwen Li (314020), Sofía Ruiz-Cruz (8597100), Jing-Ren Zhang (271032), Alicia Bravo (4886896), Manuel Espinosa (25471), Juanjuan Wang (1807810)   +5 more
core   +1 more source