Results 91 to 100 of about 274,745 (274)

RNGU-NET: a novel efficient approach in Segmenting Tuberculosis using chest X-Ray images [PDF]

PeerJ Computer Science
Tuberculosis affects various tissues, including the lungs, kidneys, and brain. According to the medical report published by the World Health Organization (WHO) in 2020, approximately ten million people have been infected with tuberculosis.
Fuat Turk
doaj   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Deep learning-enabled generative acceleration for topology-optimized structures in 2D and 3D domain

Discover Artificial Intelligence
Latest research explored into how Deep Learning (DL) can be used to accelerate topology optimization while reducing processing costs. Topology optimization, relying on finite element analysis (FEA) and iterative solvers, typically incurs substantial ...
S Kanmani, M. Murali
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Perbandingan Model U-Net dan ELU-Net untuk Segmentasi Semantik Citra Medis Kanker Pankreas

Jurnal Nasional Teknik Elektro dan Teknologi Informasi
Analisis citra medis untuk melakukan segmentasi semantik menggunakan teknologi deep learning masif dikembangkan saat ini. Salah satu pengembangannya adalah arsitektur U-Net, yang dapat menghasilkan akurasi yang baik. Pengembangan dilanjutkan menghasilkan
Algi Fari Ramdhani, Yudi Widhiyasana, Setiadi Rachmat   +2 more
doaj   +1 more source

Dilated Saliency U-Net for White Matter Hyperintensities Segmentation Using Irregularity Age Map

Frontiers in Aging Neuroscience, 2019
White matter hyperintensities (WMH) appear as regions of abnormally high signal intensity on T2-weighted magnetic resonance image (MRI) sequences. In particular, WMH have been noteworthy in age-related neuroscience for being a crucial biomarker for all ...
Yunhee Jeong, Muhammad Febrian Rachmadi, Muhammad Febrian Rachmadi, Maria del C. Valdés-Hernández, Taku Komura   +4 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

U-Net V2: Rethinking the Skip Connections of U-Net for Medical Image Segmentation

2025 IEEE 22nd International Symposium on Biomedical Imaging (ISBI)
In this paper, we introduce U-Net v2, a new robust and efficient U-Net variant for medical image segmentation. It aims to augment the infusion of semantic information into low-level features while simultaneously refining high-level features with finer details.
Peng, Yaopeng, Sonka, Milan, Chen, Danny Z.   +2 more
openaire   +2 more sources