Results 111 to 120 of about 163,795 (290)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Permian magmatism and metamorphism in the Dent Blanche nappe: constraints from field observations and geochronology [PDF]

open access: yes, 2017
In the Dent Blanche Tectonic System, the Mont Morion biotite-bearing granite is a km- scale intrusion preserved in a low-strain volume. Zircon saturation thermometry suggests that it crystallised from a melt that reached about 800 °C.
Ballèvre, Michel   +6 more
core   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Simultaneous Determination of U-Pb Age and Trace Elements of Zircon by Laser Ablation Sector Field Inductively Coupled Plasma-Mass Spectrometry

open access: yesYankuang ceshi
Laser ablation sector field inductively coupled plasma-mass spectrometry (LA-SF-ICP-MS) is widely applied in U-Pb dating of zircon due to its remarkable sensitivity.
Linghao ZHAO   +5 more
doaj   +1 more source

Shrimp U-Pb Geochronology Final Report

open access: yes, 2019
Fil: Ireland, MSc. Australian Geological Survey Organisation; Australia.
Camacho, A., Ireland, MSc, Ireland, T.R.
openaire   +1 more source

U-Th-Pb isotopic systematics of lherzolitic shergottite Yamato-793605 [PDF]

open access: yes, 1997
We have undertaken U-Th-Pb isotopic studies on lherzolitic shergottite, Yamato-793605. Four mineral separates (olivine, plagioclase, and two phases of pyroxene) and a whole-rock sample were leached with dilute acid in order to remove secondary Pb ...
Misawa,Keiji   +3 more
core   +1 more source

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