Results 141 to 150 of about 668,632 (409)

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Evidence of Multiple r-Process Sites in the Early Galaxy: New Observations of CS 22892-052

, 2000
First results are reported of a new abundance study of neutron-capture elements in the ultra-metal-poor (UMP; [Fe/H] = -3.1) halo field giant star CS 22892-052.
Christopher Sneden, George M. Fuller, Inese I. Ivans, James E. Lawler, John J. Cowan, Rosswog S., Scott Burles, Timothy C. Beers   +7 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

AGE AND PETROGENESIS OF DOLERITES ON THE MARA RIVER (SAYAN MARGINAL UPLIFT OF THE BASEMENT, SOUTHERN PART OF THE SIBERIAN CRATON)

Геодинамика и тектонофизика
This work focuses on petrological-and-geochemical features, as well as age of dolerites widespread within the basins of the Mara, Kamenka and Uvat rivers.
I. А. Izbrodin, А. G. Doroshkevich, А. B. Kotov, Е. B. Salnikova, А. E. Izokh, Е. F. Letnikova, А. V. Ivanov   +6 more
doaj   +1 more source

U‐Pb zircon ages from the Indian plate in northwest Pakistan and their significance to Himalayan and pre‐Himalayan geologic history [PDF]

, 2001
Joseph A. DiPietro, C. E. Isachsen
openalex   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Electron microprobe dating of lunar zirconolite

Journal of Analytical Science and Technology
Zirconolite is an accessary mineral occurred in the lunar basaltic and granitic rocks and contains relatively high contents of U, Th, and Pb, which is attractive for age dating.
Changkun Park, Hwayoung Kim
doaj   +1 more source

Paleoproterozoic to Cenozoic zircon U–Pb ages with Hf signatures from metamorphic rocks and granodiorite of Tokunoshima: constraints on the geotectonic subdivision of the Ryukyu island arc, Southwest Japan

, 2020
Hiroshi Yamamoto, K. Okamoto, Sun‐Lin Chung, Hao‐Yang Lee, Yuji Mita, Shuro Ueda, Masaru Terabayashi   +6 more
openalex   +1 more source

In Situ U–Th–Pb Dating of Parisite: Implication for the Age of Mineralization of Colombian Emeralds [PDF]

, 2022
Uwe Altenberger, Yamirka Rojas‐Agramonte, Yue‐Heng Yang, Jimmy Fernández-Lamus, Tobias Häger, Christina Günter, Alejandra Gonzalez-Pinzón, Felipe Charris-Leal, Julia Artel   +8 more
openalex   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source