Results 91 to 100 of about 12,575 (173)

Yeast ortholog of the Drosophila crooked neck protein promotes spliceosome assembly through stable U4/U6.U5 snRNP addition.

RNA: A publication of the RNA Society, 1999
Mutants in the Drosophila crooked neck (crn) gene show an embryonic lethal phenotype with severe developmental defects. The unusual crn protein consists of sixteen tandem repeats of the 34 amino acid tetratricopeptide (TPR) protein recognition domain ...
S. Chung, M. Mclean, Brian C. Rymond
semanticscholar   +1 more source

AtSNU13 modulates pre-mRNA splicing of RBOHD and ALD1 to regulate plant immunity

BMC Biology
Pre-mRNA splicing is a significant step for post-transcriptional modifications and functions in a wide range of physiological processes in plants. Human NHP2L binds to U4 snRNA during spliceosome assembly; it is involved in RNA splicing and mediates the ...
Yanke Jiang, Yingzhe Yue, Chongchong Lu, Muhammad Zunair Latif, Haifeng Liu, Zhaoxu Wang, Ziyi Yin, Yang Li, Xinhua Ding   +8 more
doaj   +1 more source

Transcriptomic analysis of tobacco flowering regulated by the BdFKF1 gene in Brachypodium distachyon

Guangxi Zhiwu
FKF1 is known to be a blue light-responsive gene and an important factor in regulating plant flowering through the photoperiod pathway. To explore the molecular mechanism of BdFKF1 gene in regulating flowering in tobacco plants through the photoperiod ...
YANG Longjiao1, LI Yajiao2, CHEN Xi2, MA Peijie2, LUO Wenju1, CHEN Caijun2, CHEN Ying2, LIU Xiaoxia2, WANG Xiaoli 2*
doaj   +1 more source

The yeast U5 snRNP coisolated with the U1 snRNP has an unexpected protein composition and includes the splicing factor Aar2p.

RNA (New York, N.Y.), 2001
We describe the purification and characterization of a 16S U5 snRNP from the yeast Saccharomyces cerevisiae and the identification of its proteins. In contrast to the human 20S U5 snRNP, it has a comparatively simple protein composition. In addition to the Sm core proteins, it contains only two of the U5 snRNP specific proteins, Prp8p and Snu114p ...
Gottschalk, A., Kastner, B., Luehrmann, R., Fabrizio, P.   +3 more
openaire   +2 more sources

Discovery of spiro[indole-3,2'-pyrrolidin]-2(1H)-one based inhibitors targeting Brr2, a core component of the U5 snRNP.

Bioorganic & Medicinal Chemistry, 2017
M. Ito, Misa Iwatani, Takeshi Yamamoto, Toshio Tanaka, T. Kawamoto, D. Morishita, Atsushi Nakanishi, Hironobu Maezaki   +7 more
semanticscholar   +1 more source

PS.120 UBR5-dependent quality control of the U5 snRNP via R2TP-mediated recognition

Molecular & Cellular Proteomics

semanticscholar   +1 more source

An evolutionarily conserved U5 snRNP‐specific protein is a GTP‐binding factor closely related to the ribosomal translocase EF‐2

EMBO Journal, 1997
P. Fabrizio, B. Laggerbauer, J. Lauber, William Arbuthnot Sir Lane, R. Lührmann   +4 more
semanticscholar   +1 more source

Investigation into the Saccharomyces cerevisiae U5 snRNP, a core spliceosome component

, 2010
The U5 snRNP is a major component of the yeast spliceosome, being part of the U4/U6.U5 tri-snRNP, the precatalytic spliceosome and the catalytically activated spliceosome. The U5 snRNP includes, at its heart, the U5 snRNA which contains the invariant Loop 1 that functions in tethering and aligning exons during splicing.
openaire   +2 more sources

Mammalian PRP4 Kinase Copurifies and Interacts with Components of Both the U5 snRNP and the N-CoR Deacetylase Complexes

Molecular and Cellular Biology, 2002
G. Dellaire, E. Makarov, J. Cowger, D. Longman, H. Sutherland, R. Lührmann, J. Torchia, W. Bickmore   +7 more
semanticscholar   +1 more source

<i>Entamoeba histolytica</i> spliceosome structural components. [PDF]

Microbiology (Reading)
Canela-Pérez I, Saucedo-Cárdenas O, Avila-Bonilla RG, Galindo-Rosales JM, Valdés J.   +4 more
europepmc   +1 more source