Neuronal differentiation regulator CEND1 coordinately suppresses tumor growth and energetics via AMPK signaling in brain glioma. [PDF]
Shu Y +9 more
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RASA2 deletion rescues immune synapse dysfunction, enhancing CAR T cell efficacy against DMGs. [PDF]
Ibanez-Vega J +12 more
europepmc +1 more source
An alternative EGFR activation by patient-derived R252C mutation promotes cancer progression. [PDF]
Zhang Y +13 more
europepmc +1 more source
Modulation of Wnt/β-Catenin Pathway by Aesculus hippocastanum Extract Enhances Temozolomide Sensitivity in Glioblastoma Cells. [PDF]
Scuderi SA +8 more
europepmc +1 more source
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Analysis of U87 glioma cells by dielectrophoresis
ELECTROPHORESIS, 2022AbstractGlioblastoma multiforme is the most aggressive and invasive brain cancer consisting of genetically and phenotypically altering glial cells. It has massive heterogeneity due to its highly complex and dynamic microenvironment. Here, electrophysiological properties of U87 human glioma cell line were measured based on a dielectrophoresis phenomenon
Esra Sengul +4 more
openaire +3 more sources
Comparison of metabolite profiles in U87 glioma cells and mesenchymal stem cells
BioSystems, 2011Gas chromatography-mass spectrometry (GC-MS) profiles were generated from U87 glioma cells and human mesenchymal stem cells (hMSC). 37 metabolites representing glycolysis intermediates, TCA cycle metabolites, amino acids and lipids were selected for a detailed analysis.
Joachim Selbig
exaly +4 more sources
Glioblastoma (GBM) remains the most lethal brain tumor without any curative treatment. Exosomes can mediate cell-to-cell communication, and may function as a new type of targeted therapy. In this study, the therapeutic benefits of exosomes generated by U87 cells treated with curcumin and/or temozolomide were investigated.
Seyed Mojtaba, Mousavi +9 more
openaire +2 more sources
Proapoptotic effect of Ginkgo biloba extract on U87 glioma cells
Objective To study the pro‐apoptotic effect of Ginkgo biloba extract on U87 glioma cells. Methods After 24 hours of Ginkgo biloba extract intervention, the proliferation of U87 glioma cells was observed by CCK‐8 with different ...
Chunyan Hao +4 more
exaly +2 more sources
Lysophosphatidylserine stimulates chemotactic migration in U87 human glioma cells
Biochemical and Biophysical Research Communications, 2008Lysophosphatidylserine (LPS) was found to stimulate intracellular calcium increase in U87 human glioma cells. LPS also stimulated chemotactic migration of U87 human glioma cells, which was completely inhibited by pertussis toxin (PTX). Moreover, LPS was also found to stimulate ERK, p38 MAPK, JNK, and Akt activities in U87 cells.
Sun Young, Lee +7 more
exaly +3 more sources
Metabolic Impact of Anti-Angiogenic Agents on U87 Glioma Cells
Glioma cells not only secrete high levels of vascular endothelial growth factor (VEGF) but also express VEGF receptors (VEGFR), supporting the existence of an autocrine loop. The direct impact on glioma cells metabolism of drugs targeting the VEGF pathway, such as Bevacizumab (Bev) or VEGFR Tyrosine Kinase Inhibitor (TKI), is poorly known.U87 cells ...
Mesti, Tanja +6 more
exaly +7 more sources

