Results 191 to 200 of about 23,643 (220)

MicroRNA-107 Inhibits U87 Glioma Stem Cells Growth and Invasion

Cellular and Molecular Neurobiology, 2013
Glioma stem cells (GSCs) are thought to be critical for resistance to radiotherapy and chemotherapy and for tumor recurrence after surgery in glioma patients. Identification of new therapeutic strategies that can target GSCs may thus be critical for improving patient survival.
Lei, Chen, Xiang-rong, Chen, Fan-fan, Chen, Yi, Liu, Peng, Li, Run, Zhang, Ke, Yan, Yong-jun, Yi, Zhi-min, Xu, Xiao-Dan, Jiang   +9 more
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Cytotoxic Effects of Ferula Latisecta on Human Glioma U87 Cells

Drug Research, 2019
AbstractGlioblastoma multiforme (GBM) is the fatal type of astrocytic tumors with a survival rate of 12 months. The present study, for the first time, evaluated the cytotoxic impacts of Ferula latisecta (F. latisecta) hydroalcoholic extract on U87 GBM cell line.
Mohammad, Jalili-Nik, Hamed, Sabri, Ehsan, Zamiri, Mohammad, Soukhtanloo, Mostafa Karimi, Roshan, Azar, Hosseini, Hamid, Mollazadeh, Mohammad Mahdi, Vahedi, Amir R, Afshari, Seyed Hadi, Mousavi   +9 more
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Proteomic level changes associated with S3I201 treated U87 glioma cells

Journal of Proteomics, 2017
Glioblastoma multiforme is Grade IV brain tumor associated with high mortality and limited therapeutics. Signal Transducer and Activator of Transcription 3 (STAT3) is persistently active in several cancers including gliomas, and plays a major role in disease progression and survival of glioma patients, thus being a potential therapeutic target for ...
JAIN, R, ATAK, A, YEOLA, A, SRIVASTAVA, S   +3 more
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MiR-181b suppresses proliferation of and reduces chemoresistance to temozolomide in U87 glioma stem cells [PDF]

Journal of Biomedical Research, 2010
MicroRNAs regulate self renewal and differentiation of cancer stem cells. There, we sought to identify the expression of miR-181b in glioma stem cells and investigate the biological effect of miR-181b on glioma stem cells in this study. MiR-181b expression was measured by real-time PCR in glioma stem cells isolated from U87 cells by FACS sorting. After
Yongping You
exaly   +3 more sources

CBX3 promotes glioma U87 cell proliferation and predicts an unfavorable prognosis

Journal of Neuro-Oncology, 2019
Chromobox protein homolog 3 (CBX3) is one of the heterochromatin protein 1 (HP1) family members. Among multiple cancers, it is usually overexpressed. However, the mechanism and function of CBX3 in glioma remain incompletely illustrated.The expression level of CBX3 as well as its correlation with glioma are detected through TCGA and Oncomine database ...
Shu-Peng Zhao, Fan Wang, Ming Yang, Xiang-Yang Wang, Cai-Ling Jin, Qian-Kun Ji, Shuai Li, Xin-Li Zhao   +7 more
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Polyamidoamine-Based Nanovector for The Efficient Delivery of Methotrexate to U87 Glioma Cells

Nanomedicine, 2020
The purpose of this study was to design a polyamidoamine (PAMAM)-based nanovector for the efficient delivery of methotrexate to U87 glioma cells. To this end, 0-100% acetylated PAMAM dendrimers of the fourth generation were synthesized and evaluated using drug encapsulation measurements, molecular dynamics simulations, neurotoxicity assays and neuronal
Natalia Ortiz, Pilar A Vásquez, Felipe Vidal, Carola F Díaz, José L Guzmán, Verónica A Jiménez, Joel B Alderete   +6 more
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Anvirzel^TMregulates cell death through inhibiting GSK-3 activity in human U87 glioma cells

Neurological Research, 2020
Objectives: Cardiac glycosides are used as potential anti-cancer agents due to their effects on the inhibition of proliferation and induction of apoptosis and/or autophagy in cancer cells. Herein, we aimed to study the potential signaling pathways taken role in differential cell-death properties of AnvirzelTM which is consisted of two toxic cardiac ...
Sule Terzioglu-Usak, Arife Nalli, Birsen Elibol, Erdinc Ozek, Mustafa Aziz Hatiboglu   +4 more
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Tamoxifen Increases Photodynamic Therapeutic Response of U87 and U25ln Human Glioma Cells

Journal of Neuro-Oncology, 2002
We tested the hypothesis that Tamoxifen (TMX), an inhibitor of protein kinase C (PKC), augments the cytotoxicity of photodynamic therapy (PDT) treatment of human (U87) and (U25ln) glioma cells. U87 and U25ln glioma cells were plated and treated with PDT using Photofrin as the sensitizer.
Feng, Jiang, Kyung-Keun, Cho, Tom, Mikkelse, Ling, Tong, Young S, Lew, Nechama, Hochbaum, Josef, Shargorodsky, Michael, Chop   +7 more
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CREB1 regulates glucose transport of glioma cell line U87 by targeting GLUT1

Molecular and Cellular Biochemistry, 2017
Glioma is stemmed from the glial cells in the brain, which is accounted for about 45% of all intracranial tumors. The characteristic of glioma is invasive growth, as well as there is no obvious boundary between normal brain tissue and glioma tissue, so it is difficult to resect completely with worst prognosis.
Jiaying, Chen, Can, Zhang, Yang, Mi, Fuxue, Chen, Dongshu, Du   +4 more
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Quantitative Proteomics Analysis Reveals Nuclear Perturbation in Human Glioma U87 Cells treated with Temozolomide

Cell Biochemistry and Function, 2019
Glioblastoma (GBM) is the most malignant and aggressive glioma, which has a very poor prognosis. Temozolomide (TMZ) is still a first‐line treatment, but resistance is inevitable even in MGMT‐deficient glioblastoma cells. The aims of this study were to comprehend the effect of TMZ on nucleus and the underlying mechanism of acquired TMZ resistance in ...
Jinglin Guo, Guo‐zhong Yi, Zhifeng Liu, Xuegang Sun, Runwei Yang, Manlan Guo, Yaomin Li, Ke Li, Kaishu Li, Xiran Wang, Haimin Song, Songtao Qi, Guanglong Huang, Yawei Liu   +13 more
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