Results 51 to 60 of about 15,754,334 (318)

La solución de Wittgenstein al problema del "concepto caballo", o de cómo hablar acerca de la estructura del lenguaje según el Tractatus

Co-herencia: Revista de Humanidades, 2018
El artículo propone interpretar la distinción que ofrece Wittgenstein en el Tractatus entre conceptos ordinarios y conceptos formales como una respuesta a las dificultades que se originan en la distinción fregeana entre concepto y objeto, a las cuales la
Víctor Hugo Chica Pérez
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Comprehensive molecular characterization of human colon and rectal cancer

Nature, 2012
To characterize somatic alterations in colorectal carcinoma, we conducted a genome-scale analysis of 276 samples, analysing exome sequence, DNA copy number, promoter methylation and messenger RNA and microRNA expression.
D. Muzny, M. Bainbridge, K. Chang, H. Dinh, J. Drummond, G. Fowler, C. Kovar, L. Lewis, M. Morgan, I. Newsham, J. Reid, J. Santibanez, E. Shinbrot, L. Treviño, Yuan-qing Wu, Min Wang, P. Gunaratne, L. Donehower, C. Creighton, D. Wheeler, R. Gibbs, M. Lawrence, Douglas Voet, R. Jing, K. Cibulskis, A. Sivachenko, P. Stojanov, A. McKenna, E. Lander, S. Gabriel, L. Ding, R. Fulton, D. Koboldt, T. Wylie, Jason R. Walker, D. Dooling, L. Fulton, K. Delehaunty, C. Fronick, Ryan T. Demeter, E. Mardis, R. Wilson, Andy Chu, Hye-Jung E. Chun, A. Mungall, E. Pleasance, A. G. Robertson, D. Stoll, Miruna Balasundaram, I. Birol, Y. Butterfield, E. Chuah, R. Coope, Noreen Dhalla, R. Guin, Carrie Hirst, M. Hirst, R. Holt, Darlene Lee, H. Li, Michael Mayo, Richard A. Moore, J. Schein, Jared R. Slobodan, Angela Tam, N. Thiessen, R. Varhol, Thomas Zeng, Yongjun Zhao, Steven J. M. Jones, M. Marra, A. Bass, A. Ramos, G. Saksena, A. Cherniack, S. Schumacher, B. Tabak, S. Carter, Nam Pho, Huy L. Nguyen, R. Onofrio, A. Crenshaw, K. Ardlie, R. Beroukhim, W. Winckler, M. Meyerson, A. Protopopov, Angela Hadjipanayis, E. Lee, Ruibin Xi, Lixing Yang, X. Ren, N. Sathiamoorthy, Peng-Chieh Chen, Psalm S. Haseley, Yonghong Xiao, Semin Lee, J. Seidman, L. Chin, P. Park, R. Kucherlapati, J. Auman, K. Hoadley, Ying Du, M. Wilkerson, Yan Shi, C. Liquori, S. Meng, Ling Li, Yidi J. Turman, M. D. Topal, Donghui Tan, S. Waring, Elizabeth Buda, Jesse L. Walsh, Corbin D. Jones, P. Mieczkowski, Darshan Singh, Junyuan Wu, Anisha Gulabani, Peter Dolina, T. Bodenheimer, A. Hoyle, J. Simons, Matthew G. Soloway, Lisle E. Mose, S. Jefferys, S. Balu, Brian D. O’Connor, J. Prins, Derek Y. Chiang, D. Hayes, C. Perou, T. Hinoue, D. Weisenberger, D. Maglinte, F. Pan, B. Berman, D. V. Berg, Hui Shen, T. Triche, S. Baylin, P. Laird, G. Getz, M. Noble, Doug Voat, Nils Gehlenborg, D. Dicara, Juinhua Zhang, Hailei Zhang, Chang-Jiun Wu, Spring Yingchun Liu, S. Shukla, Lihua Zhou, Pei Lin, R. Park, Marc-Danie Nazaire, James Robinson, H. Thorvaldsdóttir, J. Mesirov, V. Thorsson, Sheila M. Reynolds, Brady Bernard, R. Kreisberg, Jake Lin, L. Iype, Ryan Bressler, Timo Erkkilä, M. Gundapuneni, Yuexin Liu, Adam Norberg, Thomas Robinson, Da Yang, Wei Zhang, I. Shmulevich, J. J. Ronde, N. Schultz, E. Cerami, G. Ciriello, A. P. Goldberg, Benjamin E. Gross, A. Jacobsen, Jianjiong Gao, B. Kaczkowski, Rileen Sinha, B. A. Aksoy, Yevgeniy Antipin, B. Reva, R. Shen, B. Taylor, M. Ladanyi, C. Sander, Rehan Akbani, Nianxiang Zhang, B. Broom, Tod D. Casasent, A. Unruh, Chris Wakefield, S. Hamilton, R. Cason, K. Baggerly, J. Weinstein, D. Haussler, C. Benz, Joshua M. Stuart, S. Benz, J. Z. Sanborn, Charles J. Vaske, Jingchun Zhu, C. Szeto, G. Scott, C. Yau, S. Ng, Theodore Goldstein, K. Ellrott, E. Collisson, A. E. Cozen, D. Zerbino, C. Wilks, Brian Craft, P. Spellman, R. Penny, T. Shelton, M. Hatfield, S. Morris, P. Yena, C. Shelton, M. Sherman, J. Paulauskis, J. Gastier-Foster, Jay Bowen, N. Ramirez, Aaron D. Black, R. Pyatt, L. Wise, P. White, M. Bertagnolli, Jennifer Brown, T. Chan, Gerald C. Chu, Christine Czerwinski, F. Denstman, R. Dhir, A. Dörner, C. Fuchs, J. Guillem, M. Iacocca, H. Juhl, Andrew Kaufman, B. Kohl, X. Le, M. C. Mariano, Elizabeth N. Medina, M. Meyers, G. Nash, P. Paty, N. Petrelli, B. Rabeno, W. Richards, D. Solit, P. Swanson, L. Temple, J. Tepper, Richard A. Thorp, E. Vakiani, M. Weiser, J. Willis, G. Witkin, Z. Zeng, M. Zinner, C. Zornig, M. Jensen, R. Sfeir, A. Kahn, A. Chu, Prachi Kothiyal, Zhining Wang, E. Snyder, J. Pontius, T. Pihl, B. Ayala, M. Backus, Jessica L Walton, J. Whitmore, J. Baboud, D. Berton, M. Nicholls, Deepak Srinivasan, R. Raman, Stanley Girshik, Peter A. Kigonya, S. Alonso, Rashmi N. Sanbhadti, S. Barletta, J. Greene, D. Pot, K. Shaw, Laura A. L. Dillon, K. Buetow, Tanja Davidsen, John A. Demchok, G. Eley, M. Ferguson, P. Fielding, C. Schaefer, Margi Sheth, Liming Yang, M. Guyer, B. Ozenberger, Jacqueline D. Palchik, Jane L. Peterson, H. Sofia, E. Thomson   +312 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

On a quasigroup prolongation and its recursive differentiability

Acta et Commentationes: Ştiinţe Exacte şi ale Naturii
We consider a method of quasigroups prolongation by adding two new elements and by using two transversals that intersect in exactly one cell. In a Latin square L of order q, along with usual transversals we call "free transversals" any set of q cells ...
Elena Cuznețov
doaj   +1 more source

Small-convection limit for two-dimensional chemotaxis-Navier–Stokes system with logarithmic sensitivity and logistic-type source

Boundary Value Problems, 2022
In this paper, we consider the small-convection limit of chemotaxis-Navier–Stokes system with logarithmic sensitivity and logistic-type source { n t κ + u κ ⋅ ∇ n κ = Δ n κ − χ ∇ ⋅ ( n κ ∇ log c κ ) + f ( n κ ) , x ∈ Ω , t > 0 , c t κ + u κ ⋅ ∇ c κ = Δ c
Jie Wu
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Enhanced production of multi-strange hadrons in high-multiplicity proton–proton collisions [PDF]

Nature Physics, 2016
Quark–gluon plasma is an exotic state of matter that can emerge in heavy nuclei high-energy collisions. The ALICE collaboration reports the first observation of strangeness enhancement in proton–proton collisions, a possible signature of this state.
J. D. M. M. G. Aglieri M. N. Z. S. S. U. S. A. S. N. Adam Adamová Aggarwal Rinella Agnello Agrawal Aham, J. Adam, D. Adamová, M. Aggarwal, G. Rinella, M. Agnello, N. Agrawal, Z. Ahammed, S. Ahmad, S. Ahn, S. Aiola, A. Akindinov, S. N. Alam, D. Albuquerque, D. Aleksandrov, B. Alessandro, D. Alexandre, R. A. Molina, A. Alici, A. Alkin, J. Alme, T. Alt, S. Altinpinar, I. Altsybeev, C. A. Prado, M. An, C. Andrei, H. A. Andrews, A. Andronic, V. Anguelov, T. Anticic, F. Antinori, P. Antonioli, L. Aphecetche, H. Appelshäuser, S. Arcelli, R. Arnaldi, O. Arnold, I. Arsene, M. Arslandok, B. Audurier, A. Augustinus, R. Averbeck, M. D. Azmi, A. Badalà, Y. Baek, S. Bagnasco, R. Bailhache, R. Bala, S. Balasubramanian, A. Baldisseri, R. C. Baral, A. Barbano, R. Barbera, F. Barile, G. G. Barnaföldi, L. Barnby, V. Barret, P. Bartalini, K. Barth, J. Bartke, E. Bartsch, M. Basile, N. Bastid, S. Basu, B. Bathen, G. Batigne, A. B. Camejo, B. Batyunya, P. Batzing, I. Bearden, H. Beck, C. Bedda, N. Behera, I. Belikov, F. Bellini, H. Martinez, R. Bellwied, R. Belmont, E. Belmont-Moreno, L. Beltran, V. Belyaev, G. Bencédi, S. Beolè, I. Berceanu, A. Bercuci, Y. Berdnikov, D. Berényi, R. Bertens, D. Berzano, L. Betev, A. Bhasin, I. R. Bhat, A. Bhati, B. Bhattacharjee, J. Bhom, L. Bianchi, N. Bianchi, C. Bianchin, J. Bielcik, J. Bielčíková, A. Bilandzic, G. Bíró, R. Biswas, S. Biswas, S. Bjelogrlić, J. Blair, D. Blau, C. Blume, F. Bock, A. Bogdanov, H. Boggild, L. Boldizsár, M. Bombara, M. Bonora, J. Book, H. Borel, A. Borissov, M. Borri, F. Bossu, E. Botta, C. Bourjau, P. Braun-Munzinger, M. Bregant, T. Breitner, T. A. Broker, T. Browning, M. Broz, E. Brucken, E. Bruna, G. Bruno, D. Budnikov, H. Buesching, S. Bufalino, P. Buncic, O. Busch, Z. Buthelezi, J. Butt, J. Buxton, J. Čabala, D. Caffarri, X. Cai, H. Caines, L. Diaz, A. Calivà, E. Villar, P. Camerini, F. Carena, W. Carena, F. Carnesecchi, J. Castellanos, A. Castro, E. Casula, C. C. Sanchez, J. Cepila, P. Cerello, J. Cerkala, B. Chang, S. Chapeland, M. Chartier, J. Charvet, S. Chattopadhyay, S. Chattopadhyay, A. Chauvin, V. Chelnokov, M. Cherney, C. Cheshkov, B. Cheynis, V. Barroso, D. Chinellato, S. Cho, P. Chochula, K. Choi, M. Chojnacki, S. Choudhury, P. Christakoglou, C. H. Christensen, P. Christiansen, T. Chujo, S. Chung, C. Cicalò, L. Cifarelli, F. Cindolo, J. Cleymans, F. Colamaria, D. Colella, A. Collu, M. Colocci, G. Balbastre, Z. C. del Valle, M. Connors, J. G. Contreras, T. Cormier, Y. C. Morales, I. Maldonado, P. Cortese, M. R. Cosentino, F. Costa, J. Crkovská, P. Crochet, R. C. Albino, E. Cuáutle, L. Cunqueiro, T. Dahms, A. Dainese, M. C. Danisch, A. Danu, D. Das, I. Das, Samir R Das, A. Dash, S. Dash, S. De, A. De Caro, G. de Cataldo, C. De Conti, J. de Cuveland, A. De Falco, D. De Gruttola, N. De Marco, S. De Pasquale, R. D. de Souza, A. Deisting, A. Deloff, E. Denes, C. Deplano, P. Dhankher, D. Di Bari, A. Di Mauro, P. Di Nezza, B. Di Ruzza, M. Corchero, T. Dietel, P. Dillenseger, R. Divià, Ø. Djuvsland, A. Dobrin, D. D. Gimenez, B. Dönigus, O. Dordic, T. Drozhzhova, A. Dubey, A. Dubla, L. Ducroux, P. Dupieux, R. Ehlers, D. Elia, E. Endress, H. Engel, E. Epple, B. Erazmus, I. Erdemir, F. Erhardt, B. Espagnon, M. Estienne, S. Esumi, J. Eum, D. Evans, S. Evdokimov, G. Eyyubova, L. Fabbietti, D. Fabris, J. Faivre, A. Fantoni, M. Fasel, L. Feldkamp, A. Feliciello, G. Feofilov, J. Ferencei, A. Téllez, E. Ferreiro, A. Ferretti, A. Festanti, V. Feuillard, J. Figiel, M. Figueredo, S. Filchagin, D. Finogeev, F. Fionda, E. Fiore, M. Floris, S. Foertsch, P. Foka, S. Fokin, E. Fragiacomo, A. Francescon, A. Francisco, U. Frankenfeld, G. Fronzé, U. Fuchs, C. Furget, A. Furs, M. Girard, J. Gaardhøje, M. Gagliardi, A. Gago, K. Gajdosova, M. Gallio, C. D. Galván, D. Gangadharan, P. Ganoti, C. Gao, C. Garabatos, E. Garcia-Solis, K. Garg, C. Gargiulo, P. Gasik, E. Gauger, M. Germain, M. Gheata, P. Ghosh, S. Ghosh, P. Gianotti, P. Giubellino, P. Giubilato, E. Gladysz-dziadus, P. Glässel, D. G. Coral, A. Ramírez, A. S. Gonzalez, V. Gonzalez, P. GONZÁLEZ-ZAMORA, S. Gorbunov, L. Görlich, S. Gotovac, V. Grabski, Oleg A Grachov, L. Graczykowski, K. Graham, A. Grelli, A. Grigoras, C. Grigoras, V. Grigoriev, A. Grigoryan, S. Grigoryan, B. Grinyov, N. Grion, J. Gronefeld, J. Grosse-Oetringhaus, R. Grosso, L. Gruber, F. Guber, R. Guernane, B. Guerzoni, K. Gulbrandsen, T. Gunji, A. Gupta, R. Gupta, R. Haake, C. Hadjidakis, M. Haiduc, H. Hamagaki, G. Hamar, J. Hamon, J. W. Harris, A. Harton, D. Hatzifotiadou, S. Hayashi, S. Heckel, E. Hellbär, H. Helstrup, A. Herghelegiu, G. Corral, F. Herrmann, B. Hess, K. Hetland, H. Hillemanns, B. Hippolyte, D. Hořák, R. Hosokawa, P. Hristov, C. Hughes, T. Humanic, N. Hussain, T. Hussain, D. Hutter, D. Hwang, R. Ilkaev, M. Inaba, E. Incani, M. Ippolitov, M. Irfan, V. Isakov, M. Ivanov, V. Ivanov, V. Izucheev, B. Jacak, N. Jacazio, P. Jacobs, M. Jadhav, S. Jadlovska, J. Jadlovský, C. Jahnke, M. Jakubowska, M. Janik, P. Jayarathna, C. Jena, S. Jena, R. Bustamante, P. Jones, A. Jusko, P. Kalinak, A. Kalweit, J. Kang, V. Kaplin, S. Kar, A. Uysal, O. Karavichev, T. Karavicheva, L. Karayan, E. Karpechev, U. Kebschull, R. Keidel, D. Keijdener, M. Keil, M. M. Khan, P. Khan, S. Khan, A. Khanzadeev, Y. Kharlov, A. Khatun, B. Kileng, D. Kim, D. Kim, D. Kim, H. Kim, J. Kim, J. Kim, M. Kim, S. Kim, T. Kim, S. Kirsch, I. Kisel, S. Kiselev, A. Kisiel, G. Kiss, J. Klay, C. Klein, J. Klein, C. Klein-Bösing, S. Klewin, A. Kluge, M. L. Knichel, A. Knospe, C. Kobdaj, M. Kofarago, T. Kollegger, A. Kolojvari, V. Kondratiev, N. Kondratyeva, E. Kondratyuk, A. Konevskikh, M. Kopcik, M. Kour, C. Kouzinopoulos, O. Kovalenko, V. Kovalenko, M. Kowalski, G. K. Meethaleveedu, I. Králik, A. Kravčáková, M. Krivda, F. Krizek, E. Kryshen, M. Krzewicki, A. Kubera, V. Kučera, C. Kuhn, P. Kuijer, A. Kumar, J. Kumar, L. Kumar, S. Kumar, P. Kurashvili, A. Kurepin, A. Kurepin, A. Kuryakin, M. Kweon, Y. Kwon, S. La Pointe, P. La Rocca, P. D. de Guevara, C. L. Fernandes, I. Lakomov, R. Langoy, K. Lapidus, C. Lara, A. Lardeux, A. Lattuca, E. Laudi, R. Lea, L. Leardini, S. Lee, F. Lehas, S. Lehner, R. Lemmon, V. Lenti, E. Leogrande, I. Monzón, H. Vargas   +499 more
semanticscholar   +1 more source

Existence of nontrivial solutions for fractional Schrödinger equations with electromagnetic fields and critical or supercritical nonlinearity

Boundary Value Problems, 2020
In this paper, we study the following fractional Schrödinger equation with electromagnetic fields and critical or supercritical nonlinearity: ( − Δ ) A s u + V ( x ) u = f ( x , | u | 2 ) u + λ | u | p − 2 u , x ∈ R N , $$ (-\Delta )_{A}^{s}u+V(x)u=f ...
Quanqing Li, Kaimin Teng, Wenbo Wang, Jian Zhang   +3 more
doaj   +1 more source

The Borel-Weil theorem for reductive Lie groups

, 2015
In this manuscript we consider the extent to which an irreducible representation for a reductive Lie group can be realized as the sheaf cohomolgy of an equivariant holomorphic line bundle defined on an open invariant submanifold of a complex flag space ...
Araujo, José, Bratten, Tim
core   +1 more source