Results 251 to 260 of about 91,428 (363)

Advancing the Exploration of the Ubiquitin‐like Protein FUBI with Synthetic Chemical Tools

ChemBioChem, EarlyView.
This study unveils a novel synthetic platform by solid‐phase peptide synthesis for generating FUBI‐based chemical tools to investigate FUBIylation, a poorly understood ubiquitin‐like signaling process linked to cancer. By employing these innovative probes, we uncover novel FUBI interactors, paving the way for transformative insights into FUBI biology ...
Francesca D’Amico, Cami M. P. Talavera Ormeño, Shivanganie Poeran, Jimmy Akkermans, Rayman T. N. Tjokrodirijo, Bharath Sampadi, Peter van Veelen, Aysegul Sapmaz, Monique P. C. Mulder   +8 more
wiley   +1 more source

Knockdown of ubiquitin-conjugating enzyme E2T (UBE2T) suppresses lung adenocarcinoma progression via targeting fibulin-5 (FBLN5). [PDF]

Bioengineered, 2022
Li Y, Yang X, Lu D.
europepmc   +1 more source

Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) [PDF]

, 2006
Ryoichi Arai, S. Yoshikawa, Kazutaka Murayama, Yuzuru Imai, Ryōsuke Takahashi, Mikako Shirouzu, Shigeyuki Yokoyama   +6 more
openalex   +1 more source

Expert Perspective: Hematologic Malignancies and Vasculitis

Arthritis &Rheumatology, EarlyView.
Michelle L. Robinette, Hetty E. Carraway
wiley   +1 more source

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

European Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard, Mahmoud Abdellatif, Ioanna Andreadou, Christian Bär, Luc Bertrand, Bianca J.J.M. Brundel, Gemma Chiva‐Blanch, Sean M. Davidson, Dana Dawson, Fabio Di Lisa, Paul Evans, Zoltan Giricz, Derek J. Hausenloy, Petra Kleinbongard, Frank Lezoualc'h, Elisa Liehn, Christoph Maack, Ange Maguy, Elizabeth Murphy, Cinzia Perrino, Maurizio Pesce, Peter P. Rainer, Katrin Streckfuss‐Bömeke, Matthias Thielmann, Rong Tian, Carlo G. Tocchetti, Jolanda Van Der Velden, Sophie Van Linthout, Serena Zacchigna, Thomas Krieg   +29 more
wiley   +1 more source

Upregulation of ubiquitin-conjugating enzyme E2T (UBE2T) predicts poor prognosis and promotes hepatocellular carcinoma progression. [PDF]

Bioengineered, 2021
Ren X, Li A, Ying E, Fang J, Li M, Yu J.
europepmc   +1 more source

STIP1 drives Metabolic Reprogramming in Esophageal Squamous Cell Carcinoma via AHCY‐LDHA Axis

Exploration, EarlyView.
A schematic model illustrating that LCA can inhibit ESCC growth by inhibiting the STIP1/AHCY/LDHA axis. In brief. Jin et al. demonstrated that targeting STIP1 can significantly inhibit the progression of esophageal squamous cell carcinoma. The high expression of STIP1 increased the interaction between AHCY and LDHA and then AHCY recruits PRMT3 to ...
Guoguo Jin, Yanming Song, Mingyang Yan, Shaobo Fang, Yang Shao, Kexin Zhao, Meng Liu, Qinxin Guo, Xinyang Jia, Chengjuan Zhang, Zhenwei Wang, Kangdong Liu, Xiang Li, Simin Zhao, Mee‐Hyun Lee, Zhiping Guo, Zigang Dong   +16 more
wiley   +1 more source

Demonstration of Ubiquitin Thiolester Formation of UBE2Q2 (UBCi), a Novel Ubiquitin-Conjugating Enzyme with Implantation Site-Specific Expression1 [PDF]

, 2006
Michael H. Melner, Arthur L. Haas, Jennifer M. Klein, Alan Brash, William E. Boeglin, Subir K. Nagdas, Virginia P. Winfrey, Gary E. Olson   +7 more
openalex   +1 more source

A nanobody that binds to the backside of the ubiquitin conjugating enzyme Ube2G2 differentially affects interactions with its partner E3 Ligases. [PDF]

Commun Biol
Suresh P, Wijne C, Sun ZJ, Becht N, Sahay I, Pishesha N, Ploegh H.   +6 more
europepmc   +1 more source

Targeting E2 ubiquitin-conjugating enzyme UbcH5c by small molecule inhibitor suppresses pancreatic cancer growth and metastasis. [PDF]

Mol Cancer, 2022
Qi S, Guan X, Zhang J, Yu D, Yu X, Li Q, Yin W, Cheng XD, Zhang W, Qin JJ.   +9 more
europepmc   +1 more source