Results 261 to 270 of about 91,428 (363)

Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses [PDF]

, 2007
Toru Fukushima, Shu‐ichi Matsuzawa, Christina Kress, Jean Marie Bruey, Maryla Krajewska, Sophie Lefebvre, Juan M. Zapata, Ze’ev A. Ronai, John C. Reed   +8 more
openalex   +1 more source

Emerging Target Discovery Strategies Drive the Decoding of Therapeutic Power of Natural Products and Further Drug Development: A Case Study of Celastrol

Exploration, EarlyView.
Using celastrol as a case study, this review summarizes various target discovery strategies for natural products, including chemical proteomics, protein microarray, degradation‐based protein profiling, proteome‐wide label‐free approaches, network pharmacology, target‐based drug screening, and indirect strategies.
Yanbei Tu, Guiyu Dai, Yanyan Chen, Lihua Tan, Hanqing Liu, Meiwan Chen   +5 more
wiley   +1 more source

Analysis of Ubiquitin-Conjugating Enzyme E2T (UBE2T) Protein Levels in the Bone Marrow Biopsy Specimens of Patients With Multiple Myeloma. [PDF]

Cureus
Wang F, Yu N, Xia R.
europepmc   +1 more source

Prevalence of antibodies targeting ubiquitin-conjugating enzyme 2L3 and eukaryote translation elongation factor 1 α1 in Chinese Han and American Caucasian populations with type 1 diabetes. [PDF]

Endocr Connect, 2022
Qian L, Zhu Y, Luo Y, Zhang M, Yu L, Liu Y, Yang T.   +6 more
europepmc   +1 more source

Inactivation of the ubiquitin conjugating enzyme UBE2Q2 causes a prophase arrest and enhanced apoptosis in response to microtubule inhibiting agents [PDF]

, 2007
Sami Banerjee, William S. Brooks, David Crawford   +2 more
openalex   +1 more source

Saikosaponin b1 Attenuates Liver Fibrosis by Blocking STAT3/Gli1 Interaction and Inducing Gli1 Degradation

Exploration, EarlyView.
Saikosaponin b1 attenuates liver fibrosis by competitively disrupting the interaction between signal transducer and activator of transcription 3 (STAT3) and glioma‐associated oncogene‐1 (Gli1) in the activated hepatic stellate cells (HSCs). The blocked interaction of STAT3 and Gli1 promotes the degradation of Gli1, inhibits Gli1 transcriptional ...
Meiyu Shao, Xiaoqing Zhang, Jiamei Sun, Hongyan Dong, Xin Han, Qiao Yang, Roufen Chen, Liteng Shen, Lei Xu, Lu Wang, Bo Zhu, Dongxin Tang, Shuosheng Zhang, Keda Lu, Mengyun Peng, Gang Cao   +15 more
wiley   +1 more source

StUBC13, a Ubiquitin-Conjugating Enzyme, Positively Regulates Salt and Osmotic Stresses in Potato. [PDF]

Int J Mol Sci
Fu X, Tang X, Zhang N, Si H.
europepmc   +1 more source

Pan-Cancer Analyses of the Tumor Microenvironment Reveal That Ubiquitin-Conjugating Enzyme E2C Might Be a Potential Immunotherapy Target. [PDF]

J Immunol Res, 2021
Huang GZ, Chen ZQ, Wu J, Shao TR, Zou C, Ai YL, Lv XZ.   +6 more
europepmc   +1 more source

Effect of prolonged intravenous glucose and essential amino acid infusion on nitrogen balance, muscle protein degradation and ubiquitin-conjugating enzyme gene expression in calves [PDF]

, 2008
Fouzia Sadiq, L.A. Crompton, Jes Scaife, Michael A. Lomax   +3 more
openalex   +1 more source

Ubiquitin-conjugating enzyme Ubc13 controls breast cancer metastasis through a TAK1-p38 MAP kinase cascade

Proceedings of the National Academy of Sciences of the United States of America, 2014
Xuefeng Wu, Weizhou Zhang, Joan Font-Burgada, T. Palmer, A. Hamil, S. Biswas, M. Poidinger, N. Borcherding, Qing Xie, L. Ellies, Nikki K. Lytle, Li-Wha Wu, R. Fox, Jing Yang, S. Dowdy, T. Reya, M. Karin   +16 more
semanticscholar   +1 more source