ABSTRACT The 118 L protein in the envelope of the Invertebrate iridescent virus 6 (IIV6) is responsible for binding to receptors on the surface of permissive cells. We previously elucidated its function by silencing its gene and neutralizing the protein with antibodies.
Kubra Zengin+3 more
wiley +1 more source
An E2 ubiquitin-conjugating enzyme links diubiquitinated H2B to H3K27M oncohistone function. [PDF]
Jiao AL+4 more
europepmc +1 more source
Self‐Assembly of Noncanonical Peptides: A New Frontier in Cancer Therapeutics and Beyond
Representative examples of noncanonical peptide assemblies in anticancer therapeutics, biomaterials, regenerative medicine, molecular imaging, and catalysis are discussed, highlighting enzyme‐instructed self‐assembly as a valuable approach for constructing biomimetic and bioinspired materials that bridge the interface between biological systems and ...
Lin Bai, Meihui Yi, Bing Xu
wiley +1 more source
Ubiquitin Conjugating Enzyme E2 H (UBE2H) Is Linked to Poor Outcomes and Metastasis in Lung Adenocarcinoma. [PDF]
Yen MC+7 more
europepmc +1 more source
The Ubiquitin Conjugating Enzyme, UbcM2, Engages in Novel Interactions with Components of Cullin-3 Based E3 Ligases [PDF]
Kendra S. Plafker+2 more
openalex +1 more source
Mapping protein–protein interactions by mass spectrometry
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu+4 more
wiley +1 more source
The ubiquitin-conjugating enzyme UBE2D maintains a youthful proteome and ensures protein quality control during aging by sustaining proteasome activity. [PDF]
Hunt LC+8 more
europepmc +1 more source
The Positive Correlations between the Expression of Histopathological Ubiquitin-Conjugating Enzyme 2O Staining and Prostate Cancer Advancement. [PDF]
Kim JH+12 more
europepmc +1 more source
Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2) [PDF]
Randall C. Wilson+5 more
openalex +1 more source