Phenylethanoid Glycosides in Cistanches: Chemistry, Pharmacokinetic, and Antitumor Properties
This review systematically summarizes the representative PhGs found in CH species, their pharmacokinetic parameters, and primary metabolites in humans and rats. Additionally, it examines the antitumor activities of PhGs in CH and their associated signaling pathways against various malignancies.
Jie Li+7 more
wiley +1 more source
Dynamic Expression of Genes Encoding Ubiquitin Conjugating Enzymes (E2s) During Neuronal Differentiation and Maturation: Implications for Neurodevelopmental Disorders and Neurodegenerative Diseases. [PDF]
Paubel A+9 more
europepmc +1 more source
Structure of human ubiquitin-conjugating enzyme E2 G2 (UBE2G2/UBC7) [PDF]
Ryoichi Arai+6 more
openalex +1 more source
R. Hagglund+3 more
semanticscholar +1 more source
In SOD1 mice, symptomatic spinal microglia and astrocytes show increased autophagy flux with greater dysfunction and SOD1 inclusions in astrocytes. Dysfunction was transient (end stage glia displayed control comparable levels of autophagy parameters). ABSTRACT Amyotrophic lateral sclerosis (ALS) is defined by motor neuron death.
Nirma D. Perera+4 more
wiley +1 more source
Endoplasmic reticulum and inner nuclear membrane ubiquitin-conjugating enzymes Ubc6 and Ubc7 confer resistance to hygromycin B in Saccharomyces cerevisiae. [PDF]
Owutey SL+10 more
europepmc +1 more source
Demonstration of Ubiquitin Thiolester Formation of UBE2Q2 (UBCi), a Novel Ubiquitin-Conjugating Enzyme with Implantation Site-Specific Expression1 [PDF]
Michael H. Melner+7 more
openalex +1 more source
Ubiquitin-conjugating enzyme Ubc13 is a critical component of TNF receptor-associated factor (TRAF)-mediated inflammatory responses [PDF]
Toru Fukushima+8 more
openalex +1 more source
Two RING finger proteins mediate cooperation between ubiquitin‐conjugating enzymes in DNA repair
H. Ulrich, S. Jentsch
semanticscholar +1 more source