Results 211 to 220 of about 39,918 (341)

PO-184 Role of ubiquitin-conjugating enzymes in chromosome instability and breast cancer metastasis

open access: gold, 2018
Fernando Salvador   +6 more
openalex   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

open access: yesAdvanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang   +7 more
wiley   +1 more source

Targeted Mitochondrial ECSIT Overexpression Attenuates MASH by Increasing OTUD3 Expression

open access: yesAdvanced Science, EarlyView.
Mitochondrial ECSIT expression is reduced during MASH pathogenesis. Overexpression of mitochondrial ECSIT mitigates steatohepatitis and maintains hepatic metabolic homeostasis. Mechanistically, ECSIT enhances intramitochondrial OTUD3 expression to stabilize SIRT3 through deubiquitination, thus preserving mitochondrial function and impeding disease ...
Yuqing Jiang   +11 more
wiley   +1 more source

The N-Terminal Extension of UBE2E Ubiquitin-Conjugating Enzymes Limits Chain Assembly

open access: hybrid, 2013
Frances‐Rose Schumacher   +2 more
openalex   +1 more source

Cloning and Analysis on Full-length cDNA Sequence of Ubiquitin-conjugating Enzyme Gene from Oryza meyeriana Baill. [PDF]

open access: bronze, 2012
Chunmiao Jiang   +9 more
openalex   +1 more source

Home - About - Disclaimer - Privacy