Structure of full-length ubiquitin-conjugating enzyme E2-25K (huntingtin-interacting protein 2) [PDF]
Randall C. Wilson+5 more
openalex +1 more source
Cooperative Function of Atg8‐ and TORC1‐Mediated Activities in Yeast
The atg8Δ mutant is sensitive to rapamycin, and both lipidation‐dependent and ‐independent functions of Atg8 are necessary for survival during impaired TORC1 activity. Atg8‐ and TORC1‐mediated functions may contribute to maintaining vacuolar functions.
Yumiko Oba+6 more
wiley +1 more source
Overexpression of soybean ubiquitin-conjugating enzyme gene GmUBC2 confers enhanced drought and salt tolerance through modulating abiotic stress-responsive gene expression in Arabidopsis [PDF]
Guoan Zhou, Ruzhen Chang, Lijuan Qiu
openalex +1 more source
Role of NRP1/HDAC4/CREB/RIPK1 Axis in SARS‐CoV2 S1 Spike Subunit‐Induced Neuronal Toxicity
Extracellular SARS‐CoV2 Spike‐S1 protein via NRP1 internalizes in the cytosol of SH‐SY5Y cells. Once inside, it upregulates the epigenetic eraser HDAC4, which binds transcriptional factor CREB, causes RIPK1 up‐regulation, and therefore necroptotic cell death.
Luca Sanguigno+8 more
wiley +1 more source
Overexpression of the E2 ubiquitin–conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation [PDF]
Janine H. van Ree+3 more
openalex +1 more source
Impact of Acute Endurance Exercise on Alternative Splicing in Skeletal Muscle
Current model on the effects of acute endurance exercise on the AS regulatory mechanism with key trans‐factors/RBPs (e.g., hnRNP‐A1, ‐A3, and TIA1). ABSTRACT Alternative splicing (AS) is a highly conserved posttranscriptional mechanism, generating mRNA variants to diversify the proteome.
Alexander Ahn+5 more
wiley +1 more source
S-adenosyl methionine regulates ubiquitin-conjugating enzyme 9 protein expression and sumoylation in murine liver and human cancers [PDF]
Maria Lauda Tomasi+7 more
openalex +1 more source