Results 121 to 130 of about 305,105 (318)
Ubiquitin, ubiquitination and the ubiquitin-proteasome system in cancer [PDF]
openaire +2 more sources
The NLR protein PibH8 interacts with phenylalanine ammonia‐lyase OsPAL1 and E3 ubiquitin ligase OsFBK16. Through competitive binding, PibH8 weakens the interaction between OsFBK16 and OsPAL1, thereby reducing the degradation of OsPAL1 by OsFBK16. The Hap1 allele of PibH8 exhibits a higher expression level than Hap2, thus accumulating more PibH8 protein,
Denghao Xiang+17 more
wiley +1 more source
Chromatin conjugate protein A24 is cleaved and ubiquitin is lost during chicken erythropoiesis.
Ira L. Goldknopf+3 more
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MANF in cardiomyocytes interacts with BAX to impede BAX mitochondrial translocation and cytochrome c release, further stabilizing mitochondrial structure and energy supply to relieve myocardial apoptosis and hypertrophy, which indicates MANF as a novel cardioprotective factor to have a promising clinical application for myocardial hypertrophy ...
Dong Wang+13 more
wiley +1 more source
Ubiquitin is the ATP-dependent proteolysis factor I of rabbit reticulocytes.
Keith D. Wilkinson+2 more
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Sanggenol L, a flavonoid from mulberry, enhances glioblastoma sensitivity to temozolomide by inhibiting mitophagy and inducing apoptosis through TRIM16‐mediated OPTN degradation. In animal studies, liposomal delivery of Sanggenol L significantly improves the efficacy of its combination with TMZ, providing new insights into glioblastoma treatment ...
Hongbo Chang+11 more
wiley +1 more source
Editorial: Ubiquitin and Ubiquitin-Relative SUMO in DNA Damage Response
Kristijan Ramadan+2 more
doaj +1 more source
USP45 Represses Melanoma Development by Deubiquitinating and Stabilizing Tumor Suppressor MRGPRF
USP45 acts as a melanoma suppressor by stabilizing MRGPRF, which weakens the PI3K/AKT pathway, suppresses tumor growth, and reduces melanoma cell migration and invasion. Abstract Melanoma, a highly malignant skin cancer, has seen a rising incidence and death toll. MRGPRF is a novel melanoma suppressor that inhibits the PI3K/AKT pathway.
Wancong Zhang+10 more
wiley +1 more source